Panama City is a multicultural urban center, with large populations from many different parts of the world. Spanish is spoken by most, and many speak some form of English. There's great shopping, from high-end stores in the malls around Paitilla and in the banking district around Via Espana, to veritable bargains around La Central and the Los Pueblos outdoor mall. You can find many ethnic stores (mostly Chinese and Indian), around the city.
A visit to the Panama Canal is an absolute must if you're in Panama City. The easiest and cheapest way is to go to the Miraflores locks, watch the huge boats go by and visit its very modern and informative visitor's center. Cabs, trains and of course—boats are available from the city center to Miraflores locks.
Casco Viejo is the historic part of town, where you will find many colonial style government buildings, cathedrals and museums. The Canal Museum is currently under massive renovation, with crumbling shacks next to beautifully restored colonial buildings. The area has become a popular place for visitors to find accommodations.
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(source : wikitravel)
* Prices reflect the lowest "base rate" found over the next 30 days. Rates are subject to change and may not include taxes and fees, hotel service charges, extra person charges, or incidentals, such as room service. All rates are displayed in USD unless otherwise noted. Converted rates are provided for your convenience. They are based on today's exchange rate, but the hotel will charge you in the local currency.