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Featured Santa Cruz Business Hotels

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

$125 nightly

$125 total

Jan 4 - Jan 5, 2026

Guests staying at Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel enjoy access to a full-service spa, a gym, and a sauna. You can take advantage of free parking, along with an area shuttle. Front-desk staff can answer questions 24/7, and assist with tours or tickets, luggage storage, and dry cleaning/laundry. Other amenities at this spa hotel include free WiFi in public areas, a hot tub, and a conference center.

Pool

Hot Tub

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

$74 nightly

$74 total

Dec 20 - Dec 21

Guests of Hampton by Hilton Santa Cruz/Equipetrol, Bolivia enjoy a gym, free WiFi in public areas, and a business center. There's free parking, and a shuttle from the hotel to the airport (available 24 hours) for BOB 120 per vehicle. The front desk has multilingual staff on hand 24/7 to help with dry cleaning/laundry, securing valuables, and luggage storage. Other amenities at this luxury hotel include coffee/tea in a common area, a meeting room, and a free grocery shopping service.

Breakfast included

Parking included

$180 nightly

$180 total

Dec 25 - Dec 26

Camino Real Hotel features a full-service spa, an indoor pool, and an outdoor pool. For transportation, you can make use of an airport shuttle (available 24 hours) for BOB 115 per vehicle one way, as well as a shopping center shuttle. The front desk has multilingual staff on hand 24/7 to help with concierge services, luggage storage, and securing valuables. Other amenities at this luxury hotel include a children's pool, a gym, and a sauna.

Pool

Hot Tub

Guests staying at Senses Boutique Hotel enjoy an outdoor pool, a rooftop terrace, and free WiFi in public areas. There's free valet parking, and an airport shuttle (available 24 hours) for BOB 140 per vehicle roundtrip. Multilingual staff at the 24-hour front desk can assist with securing valuables, luggage storage, and dry cleaning/laundry. Other amenities at this family-friendly hotel include meeting rooms, a 24-hour business center, and a seasonal outdoor pool.

Pool

Breakfast included

Hotel LP Santa Cruz Centro features free WiFi in public areas, conference space, and a business center. You can take advantage of free parking, along with an airport shuttle (available 24 hours) for USD 15 per vehicle one way. Multilingual staff at the 24-hour front desk can assist with tours or tickets, luggage storage, and dry cleaning/laundry. Additional amenities include laundry facilities and a banquet hall.

Pet friendly

Parking included

Guests of Apart Hotel Premium Suites Santa Cruz enjoy free WiFi in public areas, a terrace, and laundry facilities. You can take advantage of free parking, along with an airport shuttle (available on request) for USD 24 per vehicle roundtrip. Staff members are on hand to provide tour or ticket assistance, luggage storage, and a safe deposit box at the front desk.

Kitchen

Parking included

Buganvillas Hotel Suites & Spa features an outdoor pool, a children's pool, and a gym. There's limited parking, and an airport shuttle (available 24 hours) for BWP 16 per person one-way. The 24-hour front desk has multilingual staff ready to assist with concierge services, luggage storage, and securing valuables. Other amenities at this family-friendly hotel include a sauna, free WiFi in public areas, and an outdoor tennis court.

Pool

Free WiFi

Guests staying at El Pueblito Hotel Boutique enjoy access to a winery, an outdoor pool, and free WiFi in public areas. You can take advantage of free parking, along with an airport shuttle (available on request) for USD 50 per vehicle one way. Front-desk staff can assist with securing valuables, dry cleaning/laundry, and tours or tickets. Additional amenities include a meeting room, a library, and a terrace.

Pool

Breakfast included

$59 nightly

$59 total

Dec 31 - Jan 1, 2026

Guests staying at Hotel Arenal enjoy access to 2 outdoor pools, a gym, and a sauna. There's free parking, and an airport shuttle (available 24 hours) for USD 15.00 per person one-way. The front desk is staffed 24/7 to help with securing valuables, concierge services, and dry cleaning/laundry. Additional amenities include free WiFi in public areas, a conference center, and a 24-hour business center.

Pool

Breakfast included

Guests of Hotel Asturias enjoy an outdoor pool, free WiFi in public areas, and a meeting room. There's free parking, and an airport shuttle (available 24 hours) for USD 15 per vehicle one way. Front-desk staff can answer questions 24/7, and assist with tours or tickets, dry cleaning/laundry, and luggage storage. This hotel also has a garden.

Pool

Breakfast included

Guests of Hotel California enjoy access to free WiFi in public areas, conference space, and a business center. You can take advantage of free offsite parking, along with an area shuttle. Multilingual staff at the 24-hour front desk can assist with securing valuables, dry cleaning/laundry, and luggage storage. Additional amenities include a computer station, a free grocery shopping service, and free newspapers.

Breakfast included

Free WiFi

Guests of Hotel Canciller have access to an outdoor pool, a 24-hour gym, and a sauna. You can take advantage of free parking, along with an airport shuttle (available 24 hours) for USD 14.00 per vehicle roundtrip. The front desk is staffed 24/7 to help with luggage storage, securing valuables, and tours or tickets. Additional amenities include free WiFi in public areas, a 24-hour business center, and coffee/tea in a common area.

Pool

Parking included

$69 nightly

$69 total

Dec 19 - Dec 20

At Hotel Continental Park, guests have access to an outdoor pool, a sauna, and free WiFi in public areas. There's free parking if you drive. The 24-hour front desk has staff standing by to help with securing valuables, luggage storage, and tours or tickets. Additional amenities include meeting rooms, a business center, and free newspapers.

Pool

Breakfast included

$124 nightly

$124 total

Jan 17 - Jan 18, 2026

At Hotel Cortez, guests enjoy a full-service spa, an outdoor pool, and a children's pool. There's free parking and an area shuttle. The 24-hour front desk has multilingual staff ready to assist with luggage storage, dry cleaning/laundry, and tours or tickets. Other amenities at this spa hotel include a 24-hour gym, free WiFi in public areas, and meeting rooms.

Pool

Breakfast included

At Hotel La Siesta, guests enjoy features like an outdoor pool, a children's pool, and free WiFi in public areas. Free valet and self parking are available, and there's also an airport shuttle. The 24-hour front desk has staff standing by to help with securing valuables, dry cleaning/laundry, and tours or tickets. Additional amenities include meeting rooms, a 24-hour business center, and a meeting room.

Pool

Breakfast included

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Santa Cruz Business Hotels

We get it, sometimes you have to travel for work and not play. But that doesn’t mean your hotel has to be buttoned up and boring. Orbitz has some of the best deals on Santa Cruz business hotels that will impress even the savviest executive. If you’re looking for a business-friendly hotel with amenities that allow you to get work done and also relax after a busy day, look no further.

Welcome to business class

These hotels will please even the most discerning business traveler. Whether you’re staying for a week-long conference or are just here for a quick pitch, Santa Cruz work-friendly hotels have everything you need for a productive and restful stay. When you book through Orbitz, we make it easy to choose the rates and amenities that are best for your business.

All work, all play

Put work first at these hotels. Our Santa Cruz hotels with Wi-Fi will ensure you stay connected throughout your stay. Business-friendly amenities like on-site 24/7 business centers, wired high-speed internet and room service mean you’ll have no problems finalizing your presentation. We also have Santa Cruz hotels with meeting rooms, so closing that deal or impressing new clients is just an elevator ride away.

When it’s time to clock out and kick back, these hotels keep you relaxed as possible. You could find amenities like premium bedding for resting up before that big meeting, heated pools to wind down after a long day, and gourmet dining for your favorite clients. In Santa Cruz, you can finally mix business with pleasure.

Santa Cruz Business Hotels essential information

Business Hotels in Santa Cruz	41
Highest price	$180
Cheapest price	$59
Total number of hotels in Santa Cruz	314
Popular hotels	Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel, Hampton by Hilton Santa Cruz/Equipetrol, Bolivia, Camino Real Hotel, Senses Boutique Hotel, Hotel LP Santa Cruz Centro, Apart Hotel Premium Suites Santa Cruz, Buganvillas Hotel Suites & Spa, El Pueblito Hotel Boutique, Hotel Arenal, Hotel Asturias, Hotel California, Hotel Canciller, Hotel Continental Park, Hotel Cortez, Hotel La Siesta