Hotels in Defiance
Search over 830 hotels from $73 total
Earn Orbucks instantly: $1 Orbuck = $1 USD, good toward hotels
Save 10% or more on select hotels with Insider Prices
Book on the app to instantly earn 5% on 350,000+ hotels
Top Rated Defiance Hotels
Hollywood Casino & Hotel St. Louis
777 Casino Center Drive, Maryland Heights, MO
Free Cancellation
Reserve now, pay when you stay
18.13 mi from city center
$111 nightly
The price is $130 total per night
$130 total
May 25 - May 26
Total includes taxes and fees
Guests of Hollywood Casino & Hotel St. Louis have access to a casino, a 24-hour gym, and meeting rooms. If you decide to drive, there's free parking. Front-desk staff can answer questions 24/7, and assist with luggage storage, concierge services, and securing valuables. Additional amenities include conference space, a 24-hour business center, and express check-out.
Parking included
Restaurant
Sonesta ES Suites St. Louis - Chesterfield
15431 Conway Rd, Chesterfield, MO
Free Cancellation
Reserve now, pay when you stay
12.28 mi from city center
$96 nightly
The price is $112 total per night
$112 total
Jun 1 - Jun 2
Total includes taxes and fees
Sonesta ES Suites St. Louis - Chesterfield features a 24-hour gym, free WiFi in public areas, and a 24-hour business center. There's free parking if you drive. Front-desk staff can answer questions 24/7, and assist with luggage storage, dry cleaning/laundry, and securing valuables. If you like to take your furry friend along on your adventures, this pet-friendly property offers food and water bowls. Additional amenities include a seasonal outdoor pool, a computer station, and express check-out.
Pool
Breakfast included
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
1088 South Highway Drive, Fenton, MO
Free Cancellation
17.91 mi from city center
$94 nightly
The price is $109 total per night
$109 total
May 18 - May 19
Total includes taxes and fees
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham features an indoor pool, an outdoor pool, and a gym. You can take advantage of free parking if you drive. The 24-hour front desk has staff standing by to help with dry cleaning/laundry and luggage storage. Additional amenities include free WiFi in public areas, meeting rooms, and a business center.
Pool
Breakfast included
Ameristar Casino Resort and Spa
1 Ameristar Blvd, St. Charles, MO
Free Cancellation
Reserve now, pay when you stay
18.31 mi from city center
$183 nightly
The price is $214 total per night
$214 total
May 21 - May 22
Total includes taxes and fees
Guests of Ameristar Casino Resort and Spa have access to a full-service spa, a casino, and a 24-hour gym. The 24-hour front desk has multilingual staff ready to assist with luggage storage and concierge services. Other amenities at this luxury hotel include 2 hot tubs, a conference center, and a seasonal outdoor pool.
Pool
Hot Tub
The Wildwood Hotel
2801 Fountain Pl, Wildwood, MO
Free Cancellation
Reserve now, pay when you stay
8.76 mi from city center
$101 nightly
The price is $118 total per night
$118 total
May 26 - May 27
Total includes taxes and fees
Guests staying at The Wildwood Hotel enjoy an indoor pool, a gym, and free WiFi in public areas. You can put free parking to good use if you drive. The 24-hour front desk has staff standing by to help with luggage storage, and answer any questions about the accommodations. Additional amenities include a hot tub, meeting rooms, and conference space.
Pool
Hot Tub
Wingate by Wyndham St. Louis/Fenton Route 66
1100 S Highway Dr, Fenton, MO
Free Cancellation
Reserve now, pay when you stay
17.88 mi from city center
$85 nightly
The price is $98 total per night
$98 total
May 18 - May 19
Total includes taxes and fees
Wingate by Wyndham St. Louis/Fenton Route 66 features an outdoor pool, free WiFi in public areas, and coffee in a common area. Free parking is available if you drive. The front desk is staffed 24 hours a day to help with securing valuables and luggage storage. Additional amenities include express check-out, a TV in a common area, and a vending machine.
Pool
Breakfast included
La Quinta Inn & Suites by Wyndham St. Louis Westport
11805 Lackland Rd, Maryland Heights, MO
Free Cancellation
Reserve now, pay when you stay
19.04 mi from city center
$86 nightly
The price is $99 total per night
$99 total
May 18 - May 19
Total includes taxes and fees
Guests of La Quinta Inn & Suites by Wyndham St. Louis Westport have access to an outdoor pool, a gym, and free WiFi in public areas. You can take advantage of free parking, along with a free airport shuttle during limited hours. The 24-hour front desk has multilingual staff ready to help with luggage storage, and answer any questions about the area. Additional amenities include conference space, a business center, and coffee/tea in a common area.
Pool
Breakfast included
Crowne Plaza St. Louis Airport by IHG
11228 Lone Eagle Dr, Bridgeton, MO
Free Cancellation
21.82 mi from city center
$133 nightly
The price is $157 total per night
$157 total
May 18 - May 19
Total includes taxes and fees
At Crowne Plaza St. Louis Airport by IHG, guests enjoy an indoor pool, a gym, and free WiFi in public areas. If you drive, self parking is USD 10.00 per night, or you can take advantage of the free airport shuttle (available 24 hours). The front desk is staffed 24/7 to help with concierge services, securing valuables, and dry cleaning/laundry. Additional amenities include meeting rooms, conference space, and a 24-hour business center.
Pool
Free airport shuttle
Hyatt Place St. Louis/Chesterfield
333 Chesterfield Center East, Chesterfield, MO
Free Cancellation
Reserve now, pay when you stay
11.78 mi from city center
$127 nightly
The price is $147 total per night
$147 total
Jun 1 - Jun 2
Total includes taxes and fees
Guests staying at Hyatt Place St. Louis/Chesterfield enjoy an indoor pool, a 24-hour gym, and free WiFi in public areas. You can put free parking to good use if you drive. The 24-hour front desk has staff standing by to help with luggage storage, dry cleaning/laundry, and securing valuables. Additional amenities include meeting rooms, conference space, and a 24-hour business center.
Pool
Breakfast included
Drury Plaza Hotel St. Louis Chesterfield
355 Chesterfield Ctr, Chesterfield, MO
Free Cancellation
Reserve now, pay when you stay
11.78 mi from city center
$130 nightly
The price is $151 total per night
$151 total
May 18 - May 19
Total includes taxes and fees
Drury Plaza Hotel St. Louis Chesterfield features an indoor pool, an outdoor pool, and a gym. If you drive, take advantage of free parking. The front desk is staffed 24 hours a day to help with securing valuables and dry cleaning/laundry. Additional amenities include free WiFi in public areas, a hot tub, and meeting rooms.
Pool
Hot Tub
Relax Inn Saint Charles
3800 Harry S Truman Blvd, St. Charles, MO
Free Cancellation
16.17 mi from city center
$64 nightly
The price is $73 total per night
$73 total
May 15 - May 16
Total includes taxes and fees
Guests staying at Relax Inn Saint Charles enjoy free WiFi in public areas, laundry facilities, and a vending machine. If you drive, take advantage of free parking. Front-desk staff are standing by 24/7 to assist with any requests.
Parking included
Free WiFi
Best Western Plus St. Louis West-Westport
12220 Dorsett Rd, Maryland Heights, MO
Free Cancellation
Reserve now, pay when you stay
18.83 mi from city center
$85 nightly
The price is $98 total per night
$98 total
May 20 - May 21
Total includes taxes and fees
Best Western Plus St. Louis West-Westport features a gym, free WiFi in public areas, and meeting rooms. There's free parking if you drive. The 24-hour front desk has staff standing by to help with securing valuables, luggage storage, and dry cleaning/laundry. Additional amenities include a business center, a seasonal outdoor pool, and coffee/tea in a common area.
Pool
Breakfast included
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
How much is a Defiance hotel?
Check Defiance hotel room prices by star rating
4 Star Hotels
7 properties
Top reasons to visit Defiance
- Wineries Galore: Defiance is a wine lover's paradise, with nearby wineries offering delightful tastings that will make your taste buds dance.
- Nature's Playground: Get your hiking boots ready and explore the breathtaking natural parks and trails that will leave you in awe of Mother Nature.
- Step Back in Time: History buffs rejoice! Defiance is packed with attractions and historic sites that will transport you to a bygone era.
- Entertainment Extravaganza: From destination activities to outdoor adventures, Defiance offers a wide range of entertainment options to keep you thoroughly entertained.
- A Town for All: Whether you're a wine enthusiast, nature lover, or history buff, Defiance has something for everyone to enjoy. Don't miss out!
Popular hotels in Defiance
Defiance, Missouri, a charming outdoor destination, offers a range of hotel options to suit every traveler's taste and budget. From rustic lodges nestled in the heart of nature to modern hotels with all the amenities, Defiance has something for everyone. Whether you're looking for a luxurious retreat or a budget-friendly stay, you'll find a variety of choices. Don't forget to check out hotel reviews and compare prices to find the best deals and cheap hotels in Defiance, Missouri.
- Clayton Plaza Hotel & Extended Stay - Located 23.9 miles away from Defiance, this 3.5-star hotel offers close proximity to friendly people, arcade, and breakfast. With amenities like free airport transportation, a wedding venue, indoor and outdoor pools, sauna, and university nearby, it is a great option for your outdoor vacation.
- Pear Tree Inn St. Louis Airport - This 2.5-star hotel is located 23.2 miles away from Defiance and provides easy access to friendly people, transportation services, and free airport transportation. It also offers amenities such as connecting rooms, smoking area, fitness center, and sports. Perfect for your outdoor vacation needs.
- Hollywood Casino & Hotel St. Louis - Situated 18.2 miles away from Defiance, this 3.5-star hotel is ideal for outdoor enthusiasts with its close proximity to a casino, live music, and friendly people. Additionally, it offers amenities like rock climbing, access to the river, free airport transportation, and a theater. A great choice for your outdoor vacation.
Top things to see and do in Defiance
Located in the charming town of Defiance, Missouri, there are plenty of activities to keep travelers entertained. Whether you're a wine enthusiast, nature lover, or history buff, Defiance has something for everyone. Explore the nearby wineries and indulge in wine tastings, or take a hike through the picturesque natural parks and trails. For history enthusiasts, there are many attractions and historic places to visit, allowing you to delve into the rich history of the area. From destination activities to a wide range of things to do, Defiance offers a variety of entertainment spots and outdoor activities to keep visitors engaged.
- Chandler Hill Vineyards: Immerse yourself in the beauty of the countryside while sipping on exquisite wines. Enjoy the enchanting atmosphere of the winery, surrounded by picturesque vineyards and rolling hills. Indulge in a romantic dinner at their charming restaurant, or dance the night away at one of their lively events. Friendly staff and a warm ambiance make this a perfect spot for a memorable experience.
- Historic Daniel Boone Home and Heritage Center: Step back in time as you explore the historic home of the legendary pioneer, Daniel Boone. Wander through nature trails that lead to secluded spots, where you can dance under the stars during festivals. Discover the rich culture and heritage of the region, surrounded by beautiful forests and scenic wineries. Engage with friendly locals who are passionate about preserving history and enjoy the tranquility of a nearby lake.
- August A. Busch Memorial Conservation Area: Immerse yourself in nature at this expansive conservation area. Dance through the lush landscapes and witness stunning birdwatching opportunities. Enjoy a friendly game of baseball with your family or dine in the midst of beautiful gardens filled with colorful flowers. Take exciting excursions through the area and marvel at the diverse wildlife. This family-friendly destination offers a perfect blend of outdoor activities and peaceful surroundings.
Seasonal travel trends of Defiance
The popularity of Defiance shows a slight change throughout the year. The most popular time to visit is between July and September, with a seasonal peak in July. The off-peak tourist season is from November and January, with December typically being the quietest month.
Check out the month-by-month weather chart for Defiance to help you plan your next trip. With a monthly average of 79.0 degrees Fahrenheit, you can expect the hottest temperatures in July. The coldest month, on average, is January. The most rainfall typically happens in May. Regardless of when you visit Defiance, every season has a reason to stay.
 Calendar Month |  Temperature |  Precipitation |  Cloudiness |
| January | 31.6°F (-0.2°C) | Light Rain | Mostly Cloudy |
| February | 34.7°F (1.5°C) | Light Rain | Mostly Sunny |
| March | 46.4°F (8.0°C) | Light Rain | Mostly Sunny |
| April | 55.9°F (13.3°C) | Light Rain | Mostly Sunny |
| May | 66.2°F (19.0°C) | Light Rain | Mostly Sunny |
| June | 75.9°F (24.4°C) | Light Rain | Mostly Sunny |
| July | 79.0°F (26.1°C) | Light Rain | Mostly Sunny |
| August | 77.2°F (25.1°C) | Light Rain | Mostly Sunny |
| September | 70.9°F (21.6°C) | Light Rain | Mostly Sunny |
| October | 58.5°F (14.7°C) | Light Rain | Mostly Sunny |
| November | 46.2°F (7.9°C) | Light Rain | Mostly Sunny |
| December | 37.6°F (3.1°C) | Light Rain | Mostly Sunny |
Where should you stay in Defiance?
What are some favorite hotels in Defiance?
Consider these top hotels around Defiance:
- Hollywood Casino & Hotel St. Louis is located 18.1 mi away, and this hotel has a casino, 7 restaurants, and 3 bars.
- Sonesta ES Suites St. Louis - Chesterfield is located 12.3 mi away, and this hotel has free breakfast, free WiFi, and free parking.
- Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham is located 17.9 mi away, and this hotel has free breakfast, free WiFi, and free parking.
Close to central Defiance, you'll find interesting places to visit like Chandler Hill Vineyards.
Defiance hotels essential information
Accommodation | 830 hotels |
|---|---|
Lowest Price | $73 total |
Highest Price | $214 total |
Popular hotels | Hollywood Casino & Hotel St. Louis, Sonesta ES Suites St. Louis - Chesterfield, Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham, Ameristar Casino Resort and Spa, The Wildwood Hotel, Wingate by Wyndham St. Louis/Fenton Route 66, La Quinta Inn & Suites by Wyndham St. Louis Westport, Crowne Plaza St. Louis Airport by IHG, Hyatt Place St. Louis/Chesterfield, Drury Plaza Hotel St. Louis Chesterfield, Relax Inn Saint Charles , Best Western Plus St. Louis West-Westport |
Booking tips for Defiance
Booking tips for Defiance
Find your perfect hotel with Orbitz
We strongly advocate for inclusive travel experiences, ensuring that everyone feels welcome on their next trip. When searching for ideal accommodations, utilize filters to discover eco-certified hotels or those that go above and beyond to embrace LGBTQ+ guests. Moreover, our customized filters assist in narrowing down options to hotels in close proximity to prominent attractions, featuring book now, pay later options, and more.
Travel as you are
At Orbitz, we believe that travel should be inclusive and enjoyable for everyone. From our early support of LGBTQIA rights to our commitment to creating a more welcoming world, we are here to help you celebrate who you are and where you're going. With our tools, LGBTQIA+ travelers can plan and book with confidence, including a filter to find LGBTQ-welcoming hotels where you'll be celebrated, not just tolerated.
Saving tips for your trip
If you're planning a trip to Defiance, Missouri, try to avoid the peak season from July to September and consider visiting during the off-peak season from November to January. To save money, bundle your flights, hotel, and car bookings together for a discounted price. While exploring Defiance, take advantage of the close proximities to inexpensive attractions such as local wineries, natural parks, and historical sites. These affinities offer affordable and enjoyable experiences for travelers on a budget.
Recent Reviews
The Wildwood Hotel
5/5 Excellent
"Very nice neighborhood and safe parking. Clean room for the price. Will stay again if in the St. Louis area."
A verified traveler stayed at The Wildwood Hotel
Posted 2 days ago
Areas Of Defiance
Hotels Near
Hotel Themes
More to Explore
Top Trending
Hotels
Cheap Hotels in ChesterfieldHotels with Hot Tubs in IndependenceCheap Hotels in IndependenceHotels in Valley ParkHotels in WentzvilleHotels with Hot Tubs in St. PetersHotels with Hot Tubs in Lee's SummitHotels in St. CharlesHotels with Hot Tubs in St. CharlesHotels with Hot Tubs in Maryland HeightsHotels with Hot Tubs in WentzvilleHotels in BrentwoodHotels with Hot Tubs in FentonHotels in EurekaHotels with Hot Tubs in EurekaHotels in FentonSpa Resorts & Hotels in WestonSpa Resorts & Hotels in ChesterfieldHotels with Hot Tubs in Liberty