Cheap flights from MEX to DSM (Mexico City Intl. to Des Moines Intl.)
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Cheap Flights from MEX to DSM starting at $336 One Way, $476 Round Trip
Prices starting at $476 for return flights and $336 for one-way flights to Des Moines Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
MEX
Mexico City
DSM
Des Moines
$476 Roundtrip, found 6 days ago
$476
Roundtrip
found 6 days ago
MEX
Mexico City
DSM
Des Moines
$490 Roundtrip, found 6 days ago
$490
Roundtrip
found 6 days ago
MEX
Mexico City
DSM
Des Moines
$498 Roundtrip, found 6 days ago
$498
Roundtrip
found 6 days ago
MEX
Mexico City
DSM
Des Moines
$499 Roundtrip, found 6 days ago
$499
Roundtrip
found 6 days ago
MEX
Mexico City
DSM
Des Moines
$511 Roundtrip, found 6 days ago
$511
Roundtrip
found 6 days ago
Hotel Ideas near Des Moines Intl.
Airport Hotels near Des Moines Intl.
Days Inn & Suites by Wyndham Des Moines Airport
1901 Hackley Ave Des Moines IA
The price is $75 total per night from Feb 8 to Feb 9
$75 total
per night
Feb 8 - Feb 9
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.4/10 Very Good! (1,739 reviews)
Nice
Reviewed on Jan 25, 2026
Quality Inn & Suites Des Moines Airport
5231 Fleur Dr Des Moines IA
The price is $69 total per night from Feb 8 to Feb 9
$69 total
per night
Feb 8 - Feb 9
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
7.2/10 Good! (1,003 reviews)
Room was great
Reviewed on Jan 22, 2026
Hampton Inn Des Moines-Airport
5001 Fleur Dr Des Moines IA
The price is $123 total per night from Feb 16 to Feb 17
$123 total
per night
Feb 16 - Feb 17
Stay at this hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
8.8/10 Excellent! (1,005 reviews)
Nice spot to sleep before flight easy parking. Friendly staff
Reviewed on Jan 25, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels In Des Moines
Hotel Fort Des Moines, Curio Collection by Hilton
1000 Walnut St Des Moines IA
The price is $151 total per night from Feb 25 to Feb 26
$151 total
per night
Feb 25 - Feb 26
Book a stay at this luxury hotel in Des Moines. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the clean rooms ...
9.4/10 Exceptional! (1,080 reviews)
The staff was amazing--I had booked for the wrong week and showed up. I did a chat with Expedia and they got on the phone with the staff at the hotel. There was room at the inn--so they switched the booking for me for no extra charge. I was thrilled! the staff of the hotel greeted us each day, brought ...
Reviewed on Jan 20, 2026
Ramada Tropics Resort & Conf Center by Wyndham Des Moines
5000 Merle Hay Rd Urbandale IA
The price is $78 total per night from Feb 1 to Feb 2
$78 total
per night
Feb 1 - Feb 2
Book a stay at this family-friendly hotel in Urbandale. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
5.6/10 (700 reviews)
Room a little dirty
Reviewed on Jan 22, 2026
Home2 Suites by Hilton Des Moines at Drake University
2650 University Ave. Des Moines IA
The price is $100 total per night from Feb 1 to Feb 2
$100 total
per night
Feb 1 - Feb 2
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9.2/10 Wonderful! (1,010 reviews)
Comfy beds, very nice staff, loved that my dog was welcome there. Will definitely stay there again.
Reviewed on Jan 26, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Des Moines Hotels With Airport Transportation
Days Inn & Suites by Wyndham Des Moines Airport
1901 Hackley Ave Des Moines IA
The price is $75 total per night from Feb 8 to Feb 9
$75 total
per night
Feb 8 - Feb 9
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.4/10 Very Good! (1,739 reviews)
Nice
Reviewed on Jan 25, 2026
Quality Inn & Suites Des Moines Airport
5231 Fleur Dr Des Moines IA
The price is $69 total per night from Feb 8 to Feb 9
$69 total
per night
Feb 8 - Feb 9
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
7.2/10 Good! (1,003 reviews)
Room was great
Reviewed on Jan 22, 2026
Hampton Inn Des Moines-Airport
5001 Fleur Dr Des Moines IA
The price is $123 total per night from Feb 16 to Feb 17
$123 total
per night
Feb 16 - Feb 17
Stay at this hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
8.8/10 Excellent! (1,005 reviews)
Nice spot to sleep before flight easy parking. Friendly staff
Reviewed on Jan 25, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Low Priced Des Moines Hotels
Motel 6 West Des Moines, IA
7655 Office Plaza Dr N West Des Moines IA
The price is $51 total per night from Jan 28 to Jan 29
$51 total
per night
Jan 28 - Jan 29
Stay at this motel in West Des Moines. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our ...
7.8/10 Good! (739 reviews)
Easy check in.
Reviewed on Jan 25, 2026
Cozy Rest Motel
2316 Southeast 14th Street Des Moines IA
The price is $81 total per night from Jan 28 to Jan 29
$81 total
per night
Jan 28 - Jan 29
Stay at this motel in Des Moines. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff in our reviews. Popular attractions ...
7.6/10 Good! (651 reviews)
This was a no frills place to stay but the room was nice and the front desk guy was friendly. If you are looking for a cheap but nice place to stay, check them out.
Reviewed on Sep 25, 2025
Quality Inn
1258 8th St West Des Moines IA
The price is $54 total per night from Feb 25 to Feb 26
$54 total
per night
Feb 25 - Feb 26
Book a stay at this business-friendly hotel in West Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
6.8/10 (21 reviews)
Staff was very helpful and courteous. Second time staying there. Would recommend to everyone!
Reviewed on Jan 23, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Family Friendly Hotels in Des Moines
Wildwood Lodge
11431 Forest Ave Clive IA
The price is $97 total per night from Feb 1 to Feb 2
$97 total
per night
Feb 1 - Feb 2
Stay at this hotel in Clive. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
9.4/10 Exceptional! (1,223 reviews)
Everything was great. Highly recommend.
Reviewed on Jan 26, 2026
Ramada Tropics Resort & Conf Center by Wyndham Des Moines
5000 Merle Hay Rd Urbandale IA
The price is $78 total per night from Feb 1 to Feb 2
$78 total
per night
Feb 1 - Feb 2
Book a stay at this family-friendly hotel in Urbandale. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
5.6/10 (700 reviews)
Families like: Kids pool, waterpark, game room, cribs
Travelers say...
Room a little dirty
Reviewed on Jan 22, 2026
Baymont by Wyndham Des Moines Airport
6221 Willow Creek Ave Des Moines IA
The price is $100 total per night from Jan 28 to Jan 29
$100 total
per night
Jan 28 - Jan 29
Book a stay at this family-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our ...
9.2/10 Wonderful! (1,178 reviews)
Families like: Game room, cribs, rollaway beds, games and toys
Travelers say...
Clean room and very friendly staff
Reviewed on Jan 21, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
MEX to DSM Route Info
Origin Airport | |
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Destination Airport | |
Number Of Airlines Serving | |
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- Airport Locations
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MEX Address & GPS
Address:
Mexico City ,
Mexico
IATA Code:
MEX
Longitude:
-99.072778
Latitude:
19.435278
Time Zone:
America/Mexico_City
DSM Address & GPS
Address:
5800 Fleur Drive, Suite 201
Des Moines IA, 50321-2854
United States
IATA Code:
DSM
Longitude:
-93.648087
Latitude:
41.532434
Time Zone:
America/Chicago
Other Flights from Mexico City Intl. Airport (MEX)
Other Flights to Des Moines Intl. Airport (DSM)
- Felipe Ángeles Intl. Airport (NLU)
- Toluca Intl. Airport (TLC)
- Hermanos Serdan Intl. Airport (PBC)
- Querétaro Intl. Airport (QRO)
- General Francisco Mujica Intl. Airport (MLM)
- El Tajin National Airport (PAZ)
- El Lencero Airport (JAL)
- Tamuin National Airport (TSL)
- Del Bajío Airport (BJX)
- General Juan N. Alvarez Intl. Airport (ACA)
Frequently asked questions
Map To Nearby Hotels
Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.