Cheap flights from ISP to RSW (MacArthur to Southwest Florida Intl.)

Earn rewards on top of your airline miles with Orbitz Rewards

Many airlines offer flexible change policies

Sign up to receive text alerts about your trip

Cheap Flights from ISP to RSW starting at $72 One Way, $142 Round Trip

Prices starting at $142 for return flights and $72 for one-way flights to Southwest Florida Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Fri, Sep 11 - Fri, Sep 18
ISP
Islip
RSW
Fort Myers
$142 Roundtrip, found 9 hours ago
$142
Roundtrip
found 9 hours ago
Select Breeze Airways flight, departing Fri, Sep 11 from Islip to Fort Myers, returning Fri, Sep 18, priced at $142 found 9 hours ago
Fri, Aug 28 - Wed, Sep 2
ISP
Islip
RSW
Fort Myers
$147 Roundtrip, found 2 days ago
$147
Roundtrip
found 2 days ago
Select Breeze Airways flight, departing Fri, Aug 28 from Islip to Fort Myers, returning Wed, Sep 2, priced at $147 found 2 days ago
Fri, Sep 11 - Mon, Sep 14
ISP
Islip
RSW
Fort Myers
$152 Roundtrip, found 2 days ago
$152
Roundtrip
found 2 days ago
Select Breeze Airways flight, departing Fri, Sep 11 from Islip to Fort Myers, returning Mon, Sep 14, priced at $152 found 2 days ago
Mon, Sep 21 - Wed, Sep 30
ISP
Islip
RSW
Fort Myers
$152 Roundtrip, found 3 days ago
$152
Roundtrip
found 3 days ago
Select Breeze Airways flight, departing Mon, Sep 21 from Islip to Fort Myers, returning Wed, Sep 30, priced at $152 found 3 days ago
Fri, Aug 28 - Fri, Sep 4
ISP
Islip
RSW
Fort Myers
$157 Roundtrip, found 4 hours ago
$157
Roundtrip
found 4 hours ago
Select Breeze Airways flight, departing Fri, Aug 28 from Islip to Fort Myers, returning Fri, Sep 4, priced at $157 found 4 hours ago

Hotel Ideas near Southwest Florida Intl.

Airport Hotels near Southwest Florida Intl.

Holiday Inn Express & Suites Fort Myers Airport by IHG

Holiday Inn Express & Suites Fort Myers Airport by IHG

2.5 out of 5
14567 GLOBAL PARKWAY Fort Myers FL
$75 nightly
The price is $84 total per night from Jul 4 to Jul 5
$84 total
Jul 4 - Jul 5
Total with taxes and fees
Book a stay at this business-friendly hotel in Fort Myers. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9.6/10 Exceptional! (1,102 reviews)
"Lovely stay and clean rooms"

Reviewed on Jun 19, 2026

Holiday Inn Express & Suites Fort Myers Airport by IHG
Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park

Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park

2 out of 5
10150 Daniels Pkwy Fort Myers FL
$69 nightly
The price is $77 total per night from Jun 24 to Jun 25
$77 total
Jun 24 - Jun 25
Total with taxes and fees
Book a stay at this business-friendly hotel in Fort Myers. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the clean rooms ...
8/10 Very Good! (1,691 reviews)
"Super good very cheap price and staff helpful:)"

Reviewed on Jun 21, 2026

Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park
Comfort Inn & Suites Fort Myers Airport

Comfort Inn & Suites Fort Myers Airport

2.5 out of 5
Fort Myers FL
$72 nightly
The price is $80 total per night from Jun 28 to Jun 29
$80 total
Jun 28 - Jun 29
Total with taxes and fees
Book a stay at this business-friendly hotel in Fort Myers. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.8/10 Excellent! (1,143 reviews)
"Excellent service"

Reviewed on Jun 22, 2026

Comfort Inn & Suites Fort Myers Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In Fort Myers

Baymont by Wyndham Fort Myers Central

Baymont by Wyndham Fort Myers Central

2.5 out of 5
4850 S Cleveland Ave Fort Myers FL
$64 nightly
The price is $72 total per night from Jul 4 to Jul 5
$72 total
Jul 4 - Jul 5
Total with taxes and fees
Book a stay at this business-friendly hotel in Fort Myers. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
6.8/10 (1,129 reviews)
"Bathroom facilities were clean but dated. Mel's Diner next door was excellent. Breakfast offerings sucked. Coffee but no tea, no form of eggs . We ate on the Key West ferry."

Reviewed on Jun 21, 2026

Baymont by Wyndham Fort Myers Central
Marriott Sanibel Harbour Resort & Spa

Marriott Sanibel Harbour Resort & Spa

4 out of 5
17260 Harbour Pointe Dr Fort Myers FL
$235 nightly
The price is $262 total per night from Jun 28 to Jun 29
$262 total
Jun 28 - Jun 29
Total with taxes and fees
Book a stay at this spa resort in Fort Myers. Enjoy 3 outdoor pools, a full-service spa, and 4 restaurants. Our guests praise the helpful staff and the property ...
8.6/10 Excellent! (1,004 reviews)
"The room wasn’t very clean; the shower had hair in it, and the beds had dirty spots on the sheets. One of the Valet guys says that they wich to raining because some people decided to get they on parking spot at the hotel. That guy was very rude, I don't remember his name but it was, Jun 20, the time ..."

Reviewed on Jun 21, 2026

Marriott Sanibel Harbour Resort & Spa
Hilton Garden Inn Ft Myers

Hilton Garden Inn Ft Myers

3 out of 5
12600 University Dr Fort Myers FL
$95 nightly
The price is $106 total per night from Jul 5 to Jul 6
$106 total
Jul 5 - Jul 6
Total with taxes and fees
Book a stay at this business-friendly hotel in Fort Myers. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our ...
8.8/10 Excellent! (1,004 reviews)
"Wonderful spacious room had everything we needed for our 4 night stay Mini fridge, Keurig coffee maker and microwave. Also 2 complimentary water bottles n room. Very comfortable mattress and soft clean sheets. And all at a very great rate! $91/night. We’ll be back!"

Reviewed on Jun 20, 2026

Hilton Garden Inn Ft Myers
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Fort Myers Hotels With Airport Transportation

Crowne Plaza Ft. Myers Gulf Coast by IHG

Crowne Plaza Ft. Myers Gulf Coast by IHG

4 out of 5
9931 Interstate Commerce Dr Fort Myers FL
$134 nightly
The price is $149 total per night from Jul 22 to Jul 23
$149 total
Jul 22 - Jul 23
Total with taxes and fees
Book a stay at this business-friendly hotel in Fort Myers. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and ...
9.2/10 Wonderful! (1,000 reviews)
"Front desk not welcoming and attitude was stiff. Half the time not there, oblivious or non approachable. Garbage basket in room had trash in it and candy wrapper under chair in room. Certainly not thorough. No hair dryer in room and no exhaust fan in bathroom."

Reviewed on Jun 15, 2026

Crowne Plaza Ft. Myers Gulf Coast by IHG
Travelodge by Wyndham Fort Myers Airport

Travelodge by Wyndham Fort Myers Airport

2 out of 5
13661 Indian Paint Lane Fort Myers FL
$58 nightly
The price is $64 total per night from Jun 24 to Jun 25
$64 total
Jun 24 - Jun 25
Total with taxes and fees
Book a stay at this business-friendly hotel in Fort Myers. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the ...
7.6/10 Good! (1,002 reviews)
"Proximity to the airport and rate"

Reviewed on May 31, 2026

Travelodge by Wyndham Fort Myers Airport
Baymont Inn & Suites by Wyndham Fort Myers I-75

Baymont Inn & Suites by Wyndham Fort Myers I-75

2.5 out of 5
9401 Marketplace Road Fort Myers FL
$65 nightly
The price is $72 total per night from Jul 20 to Jul 21
$72 total
Jul 20 - Jul 21
Total with taxes and fees
Book a stay at this business-friendly hotel in Fort Myers. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
6.2/10 (1,000 reviews)
"Very old property. Rooms were basically clean, but in desperate need of some updating. The bathrooms have a tub with a shower in it, but with no safety features such as nonslip strips on the floor or a safety bar to grasp onto as you’re getting in and out. The two ladies who took care of the breakfast ..."

Reviewed on Jun 6, 2026

Baymont Inn & Suites by Wyndham Fort Myers I-75
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced Fort Myers Hotels

Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park

Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park

2 out of 5
10150 Daniels Pkwy Fort Myers FL
$69 nightly
The price is $77 total per night from Jun 24 to Jun 25
$77 total
Jun 24 - Jun 25
Total with taxes and fees
Book a stay at this business-friendly hotel in Fort Myers. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the clean rooms ...
8/10 Very Good! (1,691 reviews)
"Super good very cheap price and staff helpful:)"

Reviewed on Jun 21, 2026

Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park
Travelodge by Wyndham Fort Myers North

Travelodge by Wyndham Fort Myers North

2 out of 5
13353 N Cleveland Ave North Fort Myers FL
$51 nightly
The price is $57 total per night from Jul 3 to Jul 4
$57 total
Jul 3 - Jul 4
Total with taxes and fees
Stay at this hotel in North Fort Myers. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Art of the Olympians Museum and Caloosa ...
6.2/10 (1,003 reviews)
"pool not open"

Reviewed on Jun 9, 2026

Travelodge by Wyndham Fort Myers North
Baymont Inn & Suites by Wyndham Fort Myers I-75

Baymont Inn & Suites by Wyndham Fort Myers I-75

2.5 out of 5
9401 Marketplace Road Fort Myers FL
$65 nightly
The price is $72 total per night from Jul 20 to Jul 21
$72 total
Jul 20 - Jul 21
Total with taxes and fees
Book a stay at this business-friendly hotel in Fort Myers. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
6.2/10 (1,000 reviews)
"Very old property. Rooms were basically clean, but in desperate need of some updating. The bathrooms have a tub with a shower in it, but with no safety features such as nonslip strips on the floor or a safety bar to grasp onto as you’re getting in and out. The two ladies who took care of the breakfast ..."

Reviewed on Jun 6, 2026

Baymont Inn & Suites by Wyndham Fort Myers I-75
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Fort Myers

Pink Shell Beach Resort and Marina

Pink Shell Beach Resort and Marina

4 out of 5
275 Estero Blvd Fort Myers Beach FL
$280 nightly
The price is $313 total per night from Jun 25 to Jun 26
$313 total
Jun 25 - Jun 26
Total with taxes and fees
Book a stay at this beach resort in Fort Myers Beach. Enjoy free breakfast, 3 outdoor pools, and a full-service spa. Our guests praise the breakfast and the ...
9.4/10 Exceptional! (1,393 reviews)
"From check in to check out this place was a dream. Gorgeous view from balcony of the gulf, rooms were well appointed and the beds were super cozy with upgraded bedding. Robes in the room were an added bonus. From the beach to the pool and back again. Breakfast was free and had wait staff ensuring ..."

Reviewed on Jun 19, 2026

Pink Shell Beach Resort and Marina
Sundial Beach Resort & Spa

Sundial Beach Resort & Spa

5 out of 5
1451 Middle Gulf Drive Sanibel FL
$478 nightly
The price is $533 total per night from Jul 5 to Jul 6
$533 total
Jul 5 - Jul 6
Total with taxes and fees
Book a stay at this luxury aparthotel in Sanibel. Enjoy free WiFi, free parking, and 2 outdoor pools. Our guests praise the property condition in our reviews. ...
8.6/10 Excellent! (2,659 reviews)
"What a wonderful week. The staff are so accommodating. The views were spectacular. Can’t wait to come back."

Reviewed on Jun 20, 2026

Sundial Beach Resort & Spa
South Seas

South Seas

3.5 out of 5
5400 South Seas Plantation Rd Captiva FL
Book a stay at this beach resort in Captiva. Enjoy 3 outdoor pools, 5 restaurants, and a private beach. Popular attractions Captiva Beach and Jungle Drums are ...
8.4/10 Very Good! (1,001 reviews)
"Felt like they weren’t fully staffed. There wasn’t a lot of vibes of merriment even though they have great amenities to do so. Allison at Flippers was very nice and enjoyable. Gigi at Beach House was very sweet and we enjoyed her service but have to say we had told the restaurant that it was our ..."

Reviewed on Jun 10, 2026

Get rates
South Seas
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

ISP to RSW Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
ISP Address & GPS
Address:
100 Arrivals Avenue
Islip NY, 11779
United States
IATA Code:
ISP
Longitude:
-73.097546
Latitude:
40.789314
Time Zone:
America/New_York
RSW Address & GPS
Address:
11000 Terminal Access Road
Fort Myers FL,
United States
IATA Code:
RSW
Longitude:
-81.755263
Latitude:
26.527887
Time Zone:
America/New_York

Frequently asked questions

Are there non-stop flights from ISP to RSW?
Whether you're setting off on an amazing world adventure or traveling for business purposes, a direct flight is the way to go. With Breeze Airways you can fly from ISP to Southwest Florida Intl. Airport in one easy journey.
What is the shortest flight from MacArthur Airport (ISP) to Southwest Florida Intl. Airport?
From Islip, the unique sights and sounds of Fort Myers are around 3 hours and 52 minutes away. Book your favorite seat, or perhaps even upgrade to one with a little more legroom, and get to your destination in total comfort.
How many hours flight from ISP to RSW?
Settle in and get comfy, because the average journey from MacArthur Airport to Southwest Florida Intl. Airport (RSW) is 3 hours and 55 minutes. Enjoy some wine with your meal, finally finish that book ... You'll have more than enough time to relax and enjoy the ride.
What airlines have the most flights from MacArthur Airport (ISP) to RSW?
If you want a drama-free journey, consider booking your ticket with Breeze Airways. This carrier offers 13 flights every month between Islip and Fort Myers and is one of the leading airlines operating on this route.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

More to Explore