
$199 Cheap flight deals from Jacksonville (JAX) to Des Moines (SEA)
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This Weekend's Flight Deals from Jacksonville to Des Moines
This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Airfares from $199 One Way, $351 Round Trip from Jacksonville to Des Moines
Prices starting at $351 for return flights and $199 for one-way flights to Des Moines were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Des Moines economy flight packages

Sleep Inn - SeaTac Airport
May 20 - May 27
Jacksonville (JAX) to Seattle (SEA)
Seattle (SEA) to Jacksonville (JAX)
Reviewed on Oct 11, 2025

Emerald Queen Hotel and Casino - Tacoma
May 20 - May 27
Jacksonville (JAX) to Seattle (SEA)
Seattle (SEA) to Jacksonville (JAX)
Reviewed on Jan 17, 2026

Comfort Inn & Suites Sea-Tac Airport
May 20 - May 27
Jacksonville (JAX) to Seattle (SEA)
Seattle (SEA) to Jacksonville (JAX)
Reviewed on Nov 9, 2025
More About Flying To Des Moines from Jacksonville
Route Information for Flights from Jacksonville to Des Moines
Origin Airport IATA Code | JAX |
|---|---|
Destination Airport IATA Code | SEA |
Distance | |
Direct Flight Airlines | |
Earliest Flight Arrival | |
Latest Flight Arrival |
Jacksonville to Des Moines
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Feel confident when you book your Jacksonville to Des Moines flights, a great hotel or a full vacation package that you are getting the best deal around. Orbitz’s low price guarantee assures you of peace of mind.
Flights from Jacksonville
- Jacksonville to New York
- Jacksonville to Las Vegas
- Jacksonville to Chicago
- Jacksonville to Houston
- Jacksonville to Dallas
- Jacksonville to Fort Lauderdale
- Jacksonville to Atlantic City
- Jacksonville to Orlando
- Jacksonville to Detroit
- Jacksonville to Phoenix
- Jacksonville to Washington
- Jacksonville to Los Angeles
- Jacksonville to Toronto
- Jacksonville to San Francisco
- Jacksonville to London
- Jacksonville to Paris
- Jacksonville to Hartford
- Jacksonville to Rome
- Jacksonville to Montreal
- Jacksonville to Harrisburg - Hershey
Des Moines Airports
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Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.




