
$140 Cheap flight deals from Jacksonville (JAX) to Des Moines (SEA)
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This Weekend's Flight Deals from Jacksonville to Des Moines
This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Airfares from $140 One Way, $283 Round Trip from Jacksonville to Des Moines
Prices starting at $283 for return flights and $140 for one-way flights to Des Moines were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Des Moines economy flight packages


Comfort Inn & Suites Sea-Tac Airport
Nov 14 - Nov 18
Jacksonville (JAX) to Seattle (SEA)
Reviewed on Sep 22, 2025

The Belltown Inn
Nov 14 - Nov 18
Jacksonville (JAX) to Seattle (SEA)
Reviewed on Sep 26, 2025
More About Flying To Des Moines from Jacksonville
Route Information for Flights from Jacksonville to Des Moines
Origin Airport IATA Code | JAX |
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Destination Airport IATA Code | SEA |
Distance | |
Direct Flight Airlines | |
Earliest Flight Arrival | |
Latest Flight Arrival |
Jacksonville to Des Moines
Find fantastic fares on domestic and international flights that suit your travel requirements and budget needs by heading to Orbitz. Orbitz has your cheap air tickets for flights from Jacksonville to Des Moines.
Flights from Jacksonville to Des Moines at bargain prices
Budgeting and hidden costs should be the least of your concerns when planning a trip. Your priority should be planning all the things you want to do during your stay. With our low fares on Jacksonville to Des Moines flights, you know you are getting the best deal for your vacation or business trip budget—and not incurring hidden costs or paying for over-priced tickets offered by some airlines. We want to help you enjoy your trip the way you deserve.
Remain up-to-date on your flights from Jacksonville to Des Moines
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Orbitz booking discounts for Jacksonville to Des Moines flights
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Flights from Jacksonville
- Jacksonville to New York
- Jacksonville to Las Vegas
- Jacksonville to Chicago
- Jacksonville to Houston
- Jacksonville to Dallas
- Jacksonville to Fort Lauderdale
- Jacksonville to Orlando
- Jacksonville to Detroit
- Jacksonville to Los Angeles
- Jacksonville to Washington
- Jacksonville to Phoenix
- Jacksonville to Atlantic City
- Jacksonville to San Francisco
- Jacksonville to Toronto
- Jacksonville to Hartford
- Jacksonville to London
- Jacksonville to Paris
- Jacksonville to Rome
- Jacksonville to Kansas City
- Jacksonville to Montreal
Des Moines Airports
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Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.