$199 Cheap flight deals from Knoxville (TYS) to Santa Fe (SAF)

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This Weekend's Flight Deals from Knoxville to Santa Fe

This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sun, Oct 5 - Tue, Oct 14
TYS
McGhee Tyson
ABQ
Albuquerque Intl. Sunport
$515 Roundtrip, found 1 day ago
$515
Roundtrip
found 1 day ago
Select American Airlines flight, departing Sun, Oct 5 from McGhee Tyson to Albuquerque Intl. Sunport, returning Tue, Oct 14, priced at $515 found 1 day ago

Airfares from $199 One Way, $218 Round Trip from Knoxville to Santa Fe

Prices starting at $218 for return flights and $199 for one-way flights to Santa Fe were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sat, Nov 15 - Wed, Nov 19
TYS
Knoxville
ABQ
Albuquerque
$218 Roundtrip, found 5 hours ago
$218
Roundtrip
found 5 hours ago
Select American Airlines flight, departing Sat, Nov 15 from Knoxville to Albuquerque, returning Wed, Nov 19, priced at $218 found 5 hours ago
Sat, Nov 15 - Wed, Nov 19
TYS
Knoxville
ABQ
Albuquerque
$218 Roundtrip, found 5 hours ago
$218
Roundtrip
found 5 hours ago
Select United flight, departing Sat, Nov 15 from Knoxville to Albuquerque, returning Wed, Nov 19, priced at $218 found 5 hours ago
Sat, Nov 15 - Wed, Nov 19
TYS
Knoxville
ABQ
Albuquerque
$223 Roundtrip, found 5 hours ago
$223
Roundtrip
found 5 hours ago
Select United flight, departing Sat, Nov 15 from Knoxville to Albuquerque, returning Wed, Nov 19, priced at $223 found 5 hours ago
Sat, Nov 15 - Wed, Nov 19
TYS
Knoxville
ABQ
Albuquerque
$247 Roundtrip, found 5 hours ago
$247
Roundtrip
found 5 hours ago
Select United flight, departing Sat, Nov 15 from Knoxville to Albuquerque, returning Wed, Nov 19, priced at $247 found 5 hours ago
Sat, Nov 15 - Wed, Nov 19
TYS
Knoxville
ABQ
Albuquerque
$252 Roundtrip, found 5 hours ago
$252
Roundtrip
found 5 hours ago
Select United flight, departing Sat, Nov 15 from Knoxville to Albuquerque, returning Wed, Nov 19, priced at $252 found 5 hours ago

Santa Fe economy flight packages

Price found within the past 48 hours. Click for updated prices.
Crowne Plaza Albuquerque by IHG
3.5-star property

Crowne Plaza Albuquerque by IHG

8/10 Very Good! (1,007 reviews)

Nov 8 - Nov 15

7 night stay

Knoxville (TYS) to Albuquerque (ABQ)

American Airlines • Non-stop roundtrip • Coach
Price was $674, price is now $507 per person
$507
per person
found 1 day ago
The hotel is close to the historical neighborhood but it is an older property and you can tell. My room had a balcony and was facing the street so a bit noisy with cars and motorcycles. I was surprised having a suite with 2 queen beds it didn’t include Free breakfast. They did clean the room when we were out daily so that’s good and water was only $1 do they didn’t overcharge on that.

Reviewed on Sep 16, 2025

Sandia Resort And Casino
4.0-star property

Sandia Resort And Casino

9.4/10 Exceptional! (1,202 reviews)

Nov 8 - Nov 15

7 night stay

Knoxville (TYS) to Albuquerque (ABQ)

American Airlines • Non-stop roundtrip • Coach
Save 100% on your flight
Price was $1,296, price is now $809 per person
$809
per person
found 1 day ago
Nice clean rooms and pretty area

Reviewed on Aug 12, 2025

El Verde Inn
3.5-star property

El Verde Inn

9.6/10 Exceptional! (261 reviews)

Nov 8 - Nov 15

7 night stay

Knoxville (TYS) to Albuquerque (ABQ)

American Airlines • Non-stop roundtrip • Coach
Save 100% on your flight
Price was $870, price is now $634 per person
$634
per person
found 1 day ago
Beautiful property that is quiet and very comfortable. The staff was great and I can’t wait to visit again.

Reviewed on Sep 11, 2025

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More About Flying To Santa Fe from Knoxville

Route Information for Flights from Knoxville to Santa Fe

Origin Airport IATA Code
TYS
Destination Airport IATA Code
SAF
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

Knoxville to Santa Fe

It has never been easier to find cheap Knoxville to Santa Fe flights. Orbitz has some of the best deals around to save you more money on your flight, hotel, and vacation package for the trip you have been waiting for.

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Get the Best Deals on Knoxville to Santa Fe Flights

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Frequently asked questions

What is the shortest flight from Knoxville to Santa Fe?
The fastest flight from Knoxville, TN (TYS-McGhee Tyson) to Albuquerque, NM (ABQ-Albuquerque Intl. Sunport) is 3 hours and 55 minutes. Bring something extra to help pass the time, like the latest edition of your favorite magazine or some Sudoku puzzles.
What is the cheapest day of the week to fly?
Consider flying out early in the week to save on your airfare. Orbitz data from 2021 shows that Monday is the cheapest day to depart, followed by Tuesday. Saturday showed the highest average ticket prices likely because many travelers prefer to start their vacation on a weekend.
What is the cheapest month to fly?
We won't keep you guessing, according to Orbitz data from 2021, the cheapest month to fly is February. Perfect for those who need a weekend getaway, or just a break from it all in the shortest month of the year. Be aware that the most expensive time to fly is during the height of summer in July, and in the holiday month of December.*According to flight demand on Orbitz.com from January to December 2021. Savings are subject to change based on departure location, date and destination.

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Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.