$148 Cheap flight deals from Knoxville (TYS) to Grand Island (BUF)
Earn rewards on top of your airline miles with Orbitz Rewards
Many airlines offer flexible change policies
Sign up to receive text alerts about your trip
Airfares from $148 One Way, $303 Round Trip from Knoxville to Grand Island
Prices starting at $303 for return flights and $148 for one-way flights to Grand Island were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Grand Island economy flight packages
Embassy Suites Buffalo
May 29 - Jun 1
Knoxville (TYS) to Buffalo (BUF)
Reviewed on Jun 29, 2023
Curtiss Hotel, an Ascend Collection Hotel
May 29 - Jun 1
Knoxville (TYS) to Buffalo (BUF)
Reviewed on Aug 11, 2025
The Richardson Hotel
May 29 - Jun 1
Knoxville (TYS) to Buffalo (BUF)
Reviewed on Sep 25, 2025
More About Flying To Grand Island from Knoxville
Route Information for Flights from Knoxville to Grand Island
Origin Airport IATA Code | TYS |
|---|---|
Destination Airport IATA Code | BUF |
Distance | |
Direct Flight Airlines | |
Earliest Flight Arrival | |
Latest Flight Arrival |
Knoxville to Grand Island
The best fares for Knoxville to Grand Island flights are always found on Orbitz. With superior discounts and the latest innovations in mobile access, your ideal trip starts with Orbitz.
The Easy Way to Plan Travel Cheaply
We provide access to many low-cost vacation packages and travelers can mix and match airlines when scheduling their flights for the best prices and flight times. Finding cheap tickets on flights from Knoxville to Grand Island is easy when you make Orbitz your #1 travel planner.
Book Knoxville to Grand Island Flights With Mobile Apps
Our iPhone and Android mobile apps can be used to compare and book flights from Knoxville to Grand Island. These apps are perfect for checking the status of flights, gate and baggage claims details, car rental rates, and for receiving alerts on special savings that are exclusive to mobile users. Mobile app users can even score great rates when booking hotel rooms. You can compare hotels, virtually view photo galleries, and check out user reviews using the app, as well as find out which ones are closest to you.
Orbitz also offers free travel updates that are sent to your email or mobile phone that notifies you of booking changes, disruptions in service, or delayed flights.
Increase Your Rewards While Enjoying Super Low Rates
Boost your points or miles for your frequent flyer program on certain Knoxville to Grand Island flights. Simply provide your frequent flyer information when booking flights from Knoxville to Grand Island with Orbitz and get both a low fare and travel rewards. You can enter this information in your Orbitz account profile for easy remembering in future bookings.
Flights from Knoxville
- Knoxville to New York
- Knoxville to Orlando
- Knoxville to Dallas
- Knoxville to Chicago
- Knoxville to Washington
- Knoxville to Los Angeles
- Knoxville to Houston
- Knoxville to Detroit
- Knoxville to New Orleans
- Knoxville to London
- Knoxville to Sacramento
- Knoxville to Anchorage
- Knoxville to Toronto
- Knoxville to Kansas City
- Knoxville to San Francisco
- Knoxville to Hartford
- Knoxville to Rome
- Knoxville to Paris
- Knoxville to Killeen
- Knoxville to Beijing
Knoxville Airports
Grand Island Airports
More Destinations
- Flights from Washington (IAD) to Niagara Falls (IAG)
- Flights from Los Angeles (LAX) to Niagara Falls (IAG)
- Flights from Philadelphia (PHL) to Niagara Falls (IAG)
- Flights from Boston to North Tonawanda
- Flights from Dallas to North Tonawanda
- Flights from Denver to North Tonawanda
- Flights from Ho Chi Minh City to North Tonawanda
- Flights from Minneapolis - St. Paul to North Tonawanda
- Flights from Philadelphia to North Tonawanda
- Flights from Toronto to North Tonawanda
- Flights from Roanoke to North Tonawanda
- Flights from Oakland to North Tonawanda
- Flights from Newburgh to North Tonawanda
- Flights from Milwaukee to North Tonawanda
- Flights from Colorado Springs to North Tonawanda
- Flights from Grand Rapids to North Tonawanda
- Flights from Incheon to North Tonawanda
- Flights from Bangor to North Tonawanda
- Flights from Columbia to North Tonawanda
- Flights from Chattanooga to North Tonawanda
- Flights from Grand Forks to Niagara Falls
- Flights from Honolulu to Niagara Falls
- Flights from Islip to Niagara Falls
- Flights from Anchorage to Niagara Falls
- Flights from Atlanta to Niagara Falls
- Flights from Boston to Niagara Falls
- Flights from Calgary to Niagara Falls
- Flights from Chicago to Niagara Falls
- Flights from Dallas to Niagara Falls
- Flights from Detroit to Niagara Falls
- Flights from Los Angeles to Niagara Falls
- Flights from New York to Niagara Falls
- Flights from Orlando to Niagara Falls
- Flights from Toronto to Niagara Falls
- Flights from Washington to Niagara Falls
- Flights from Edmonton to Niagara Falls
- Flights from Sacramento to Niagara Falls
- Flights from Albany to Niagara Falls
- Flights from Rockford to Niagara Falls
- Flights from Kalamazoo to Niagara Falls
- Flights from Myrtle Beach to Niagara Falls
- Flights from Fort Lauderdale to Niagara Falls
- Flights from Newark to Niagara Falls
- Flights from Richmond to Niagara Falls
- Flights from Oakland to Niagara Falls
- Flights from Atlantic City to Niagara Falls
- Flights from White Plains to Niagara Falls
- Flights from Nantucket Island to Niagara Falls
- Flights from Gainesville to Niagara Falls
- Flights from Lake Placid to Niagara Falls
- Flights from Fargo to Niagara Falls
- Flights from North Bay to Niagara Falls
- Flights from Palm Beach to Niagara Falls
- Flights from Atlanta to Tonawanda
- Flights from Austin to Buffalo
- Flights from Denver to Buffalo
- Flights from Detroit to Buffalo
- Flights from Houston to Buffalo
- Flights from Las Vegas to Buffalo
- Flights from Miami to Buffalo
- Flights from Minneapolis - St. Paul to Buffalo
- Flights from Nashville to Buffalo
- Flights from New York to Buffalo
- Flights from Philadelphia to Buffalo
- Flights from Phoenix to Buffalo
- Flights from Raleigh to Buffalo
- Flights from San Francisco to Buffalo
- Flights from Seattle to Buffalo
- Flights from Toronto to Buffalo
- Flights from Washington to Buffalo
- Flights from Pittsburgh to Buffalo
- Flights from Fort Lauderdale to Buffalo
- Flights from Florence to Amherst
- Flights from Atlanta to Amherst
- Flights from Baltimore to Amherst
- Flights from Houston to Amherst
- Flights from Los Angeles to Amherst
- Flights from Miami to Amherst
- Flights from Nashville to Amherst
- Flights from Orlando to Amherst
- Flights from Portland to Amherst
- Flights from Cabo San Lucas to Amherst
- Flights from Sacramento to Amherst
- Flights from Lynchburg to Amherst
- Flights from Des Moines to Amherst
- Flights from Fort Lauderdale to Amherst
- Flights from Richmond to Amherst
- Flights from Nassau to Amherst
- Flights from Bentonville - Fayetteville to Amherst
- Flights from Albuquerque to Amherst
- Flights from Reno to Amherst
- Flights from Oklahoma City to Amherst
- Flights from Louisville to Amherst
- Flights from San José to Amherst
- Flights from Asheville to Amherst
- Flights from Bangor to Amherst
- Flights from Lubbock to Amherst
- Flights from Bozeman to Amherst
- Flights from Chattanooga to Amherst
- Flights from Columbia to Amherst
Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.