$131 Cheap flight deals from Pittsburgh (PIT) to South Carolina Midlands (CAE)

Earn rewards on top of your airline miles with Orbitz Rewards

Many airlines offer flexible change policies

Sign up to receive text alerts about your trip

This Weekend's Flight Deals from Pittsburgh to South Carolina Midlands

This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sat, Aug 15 - Mon, Aug 17
PIT
Pittsburgh Intl.
CAE
Columbia Metropolitan
$362 Roundtrip, found 17 hours ago
$362
Roundtrip
found 17 hours ago
Select United flight, departing Sat, Aug 15 from Pittsburgh Intl. to Columbia Metropolitan, returning Mon, Aug 17, priced at $362 found 17 hours ago
Sat, Aug 15 - Sat, Aug 22
PIT
Pittsburgh Intl.
CLT
Charlotte-Douglas Intl.
$487 Roundtrip, found 3 days ago
$487
Roundtrip
found 3 days ago
Select JetBlue Airways flight, departing Sat, Aug 15 from Pittsburgh Intl. to Charlotte-Douglas Intl., returning Sat, Aug 22, priced at $487 found 3 days ago

Airfares from $131 One Way, $254 Round Trip from Pittsburgh to South Carolina Midlands

Prices starting at $254 for return flights and $131 for one-way flights to South Carolina Midlands were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Thu, Aug 27 - Fri, Aug 28
PIT
Pittsburgh
CLT
Charlotte
$254 Roundtrip, found 4 days ago
$254
Roundtrip
found 4 days ago
Select JetBlue Airways flight, departing Thu, Aug 27 from Pittsburgh to Charlotte, returning Fri, Aug 28, priced at $254 found 4 days ago
Wed, Oct 14 - Fri, Oct 16
PIT
Pittsburgh
CLT
Charlotte
$261 Roundtrip, found 1 hour ago
$261
Roundtrip
found 1 hour ago
Select JetBlue Airways flight, departing Wed, Oct 14 from Pittsburgh to Charlotte, returning Fri, Oct 16, priced at $261 found 1 hour ago
Sun, Sep 6 - Sat, Sep 12
PIT
Pittsburgh
CAE
Columbia
$292 Roundtrip, found 4 days ago
$292
Roundtrip
found 4 days ago
Select United flight, departing Sun, Sep 6 from Pittsburgh to Columbia, returning Sat, Sep 12, priced at $292 found 4 days ago
Sun, Sep 6 - Sat, Sep 12
PIT
Pittsburgh
CAE
Columbia
$292 Roundtrip, found 4 days ago
$292
Roundtrip
found 4 days ago
Select Delta flight, departing Sun, Sep 6 from Pittsburgh to Columbia, returning Sat, Sep 12, priced at $292 found 4 days ago
Sun, Sep 6 - Sat, Sep 12
PIT
Pittsburgh
CAE
Columbia
$292 Roundtrip, found 4 days ago
$292
Roundtrip
found 4 days ago
Select American Airlines flight, departing Sun, Sep 6 from Pittsburgh to Columbia, returning Sat, Sep 12, priced at $292 found 4 days ago

South Carolina Midlands economy flight packages

Price found within the past 48 hours. Click for updated prices.
The Oceanfront Litchfield Inn
3.0-star property

The Oceanfront Litchfield Inn

8.2/10 Very Good! (1,005 reviews)

Sep 10 - Sep 14

4 night stay

Pittsburgh (PIT) to Myrtle Beach (MYR)

American Airlines • Non-stop roundtrip • Coach
Price was $793, price is now $577 per person
$577
per person
found 24 hours ago
Great location oceanfront. Restaurant on site and two pools. Rooms are a bit dated but clean. FYI if you book through anyone other than the hotel, breakfast is not free. Great service at the front desk. Room was a bit pricey to not have any view but the location was great! Parking available on site for free is a plus. We’ve been twice and will probably go back.

Reviewed on Aug 9, 2026

Camelot By the Sea
3.0-star property

Camelot By the Sea

8/10 Very Good! (43 reviews)

Sep 21 - Sep 28

7 night stay

Pittsburgh (PIT) to Myrtle Beach (MYR)

Breeze Airways • Roundtrip • Coach
Save 100% on your flight
Price was $900, price is now $613 per person
$613
per person
found 1 day ago
We rented 2 condos. One was out dated and the other needed to be painted badly. Also the pan in our room was filthy dirty. But space was good and was convenient. We had a great time. Just figure out how to clean the utility closet and balcony please.

Reviewed on Aug 11, 2026

Marina Inn At Grande Dunes
4.5-star property

Marina Inn At Grande Dunes

9.4/10 Exceptional! (1,790 reviews)

Sep 12 - Sep 16

4 night stay

Pittsburgh (PIT) to Myrtle Beach (MYR)

Southwest Airlines • Roundtrip • Coach
Price was $1,122, price is now $775 per person
$775
per person
found 1 day ago
Great place we enjoyed the pool the restaurants the staff was also great!!

Reviewed on Aug 11, 2026

Don't see what you're looking for?
See all available trips from Pittsburgh to South Carolina Midlands
View all trips

More About Flying To South Carolina Midlands from Pittsburgh

Route Information for Flights from Pittsburgh to South Carolina Midlands

Origin Airport IATA Code
PIT
Destination Airport IATA Code
CAE
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

Pittsburgh to South Carolina Midlands

Great Deals on Flights From Pittsburgh to South Carolina Midlands

Spend more of your time and money at South Carolina Midlands instead of sitting at your computer, searching for discount Pittsburgh to South Carolina Midlands flights. This is why Orbitz makes it easy for you to check out destinations, plan your trip, and book your air fare, hotel, car rental, and more in just one place. Our low price guarantee means that you get great deals on flights from Pittsburgh to South Carolina Midlands.

Flights That Fit Your Budget

Traveling on a budget? Not to worry if you are using Orbitz. We monitor thousands of fares to make sure we show you the best air ticket prices available for your travel dates. Besides amazing prices on Pittsburgh to South Carolina Midlands flights, we offer you great deals on hotels, vacation packages, and last-minute getaways for the perfect trip.

Orbitz customers can receive credit for frequent flyer miles and points. Simply provide your frequent flyer details when you book qualifying Pittsburgh to South Carolina Midlands flights with Orbitz.

Search for Flights from Pittsburgh to South Carolina Midlands on the Go

Orbitz offers free mobile apps for iPad, iPhone, and Android-based devices, so even the busiest trip-planner can research and book flights from Pittsburgh to South Carolina Midlands. Find cheap Pittsburgh to South Carolina Midlands flights, research local festivities and attractions, and book reservations while sitting in the salon. Orbitz will also update you on flight delays with free alerts sent to your mobile phone or email address, so you’re never left in the dark.

More Destinations

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.