
$92 Cheap flight deals from Des Moines (DSM) to Mesa (PHX)
Earn rewards on top of your airline miles with Orbitz Rewards
Many airlines offer flexible change policies
Sign up to receive text alerts about your trip
This Weekend's Flight Deals from Des Moines to Mesa
This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Airfares from $92 One Way, $197 Round Trip from Des Moines to Mesa
Prices starting at $197 for return flights and $92 for one-way flights to Mesa were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Mesa economy flight packages

Hilton Vacation Club Scottsdale Villa Mirage
Jun 6 - Jun 8
Des Moines (DSM) to Phoenix (PHX)
Phoenix (PHX) to Des Moines (DSM)
Reviewed on Jul 6, 2024

The Scottsdale Plaza Resort & Villas
Jun 6 - Jun 8
Des Moines (DSM) to Phoenix (PHX)
Phoenix (PHX) to Des Moines (DSM)
Reviewed on Apr 25, 2025

Hotel Valley Ho
Jun 6 - Jun 8
Des Moines (DSM) to Phoenix (PHX)
Phoenix (PHX) to Des Moines (DSM)
Reviewed on Apr 16, 2025
More About Flying To Mesa from Des Moines
Route Information for Flights from Des Moines to Mesa
Origin Airport IATA Code | DSM |
---|---|
Destination Airport IATA Code | PHX |
Distance | |
Direct Flight Airlines | |
Earliest Flight Arrival | |
Latest Flight Arrival |
Des Moines to Mesa
Those who want guaranteed low prices for Des Moines to Mesa flights only need to visit Orbitz. We take advantage of the latest mobile technologies to make sure you get the best bargain on your trip and that everything goes smoothly and according to your plans.
Take Advantage of Orbitz’s Amazing Customer Service on Des Moines to Mesa Flights
We will help you from booking to boarding on flights from Des Moines to Mesa. Whether you have questions about baggage limits, seat assignments or anything else, we will be there to answer them for you.
Get Great Recommendations For Travel Ideas On Orbitz.com
We do not only get the best bargains on flights from Des Moines to Mesa, but we can tell you what to do once you get there. Whether it is a music festival, hotel recommendation or list of local attractions, Orbitz can help make your travel plan more exciting.
Combine Car Rental With Your Discount Flight For Even More Savings
Not only can we get bargain deals on flights from Des Moines to Mesa but we can book your transport as well. By combining car rental with Des Moines to Mesa flights, you can be sure to save money and start moving as soon as you hit the ground.
Use Orbitz On The Go To Stay Informed Using Your Smartphone
This convenient app works with most smartphones and allows you to see the status of flights from Des Moines to Mesa. You don’t have to worry, if something goes wrong, we’ll let you know.
Flights from Des Moines
- Des Moines to Phoenix
- Des Moines to Dallas
- Des Moines to Orlando
- Des Moines to Chicago
- Des Moines to Atlanta
- Des Moines to Los Angeles
- Des Moines to Houston
- Des Moines to Seattle
- Des Moines to New York
- Des Moines to New Orleans
- Des Moines to Detroit
- Des Moines to Charlotte
- Des Moines to Washington
- Des Moines to London
- Des Moines to Toronto
- Des Moines to San Francisco
- Des Moines to Rome
- Des Moines to Sacramento
- Des Moines to San José
- Des Moines to Hartford
Des Moines Airports
Top Trending
Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.