$164 Cheap flight deals from Des Moines (DSM) to Simpsonville (GSP)
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Airfares from $164 One Way, $325 Round Trip from Des Moines to Simpsonville
Prices starting at $325 for return flights and $164 for one-way flights to Simpsonville were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Simpsonville economy flight packages
Grand Bohemian Lodge Greenville, Autograph Collection
Oct 25 - Oct 28
Des Moines (DSM) to Greenville (GSP)
Reviewed on Sep 12, 2026
More About Flying To Simpsonville from Des Moines
Route Information for Flights from Des Moines to Simpsonville
Origin Airport IATA Code | DSM |
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Destination Airport IATA Code | GSP |
Distance | |
Direct Flight Airlines | |
Earliest Flight Arrival | |
Latest Flight Arrival |
Des Moines to Simpsonville
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Flights from Des Moines
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Des Moines Airports
Simpsonville Airports
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Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.