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Cheap Flights from Des Moines to Charleston

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Selected fares from Des Moines to Charleston

Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.

Thu, Dec 5 - Tue, Dec 10
DSM
Des Moines Intl.
to
HTS
Tri-State
$275

roundtrip

found 1 day ago

Open DSM to HTS flights search result page
Fri, Dec 6 - Tue, Dec 10
DSM
Des Moines Intl.
to
CRW
Yeager
$275

roundtrip

found 1 day ago

Open DSM to CRW flights search result page
Thu, Apr 23 - Sun, Apr 26
DSM
Des Moines Intl.
to
CRW
Yeager
$276

roundtrip

found 6 days ago

Open DSM to CRW flights search result page
Thu, Apr 23 - Sun, Apr 26
DSM
Des Moines Intl.
to
CRW
Yeager
$278

roundtrip

found 6 days ago

Open DSM to CRW flights search result page
Fri, Dec 6 - Mon, Dec 9
DSM
Des Moines Intl.
to
CRW
Yeager
$295

roundtrip

found 1 day ago

Open DSM to CRW flights search result page
Wed, Dec 4 - Mon, Dec 9
DSM
Des Moines Intl.
to
CRW
Yeager
$296

roundtrip

found 1 day ago

Open DSM to CRW flights search result page
Wed, Dec 4 - Sun, Dec 8
DSM
Des Moines Intl.
to
CRW
Yeager
$298

roundtrip

found 1 day ago

Open DSM to CRW flights search result page
Thu, Apr 23 - Sun, Apr 26
DSM
Des Moines Intl.
to
CRW
Yeager
$302

roundtrip

found 6 days ago

Open DSM to CRW flights search result page
Thu, Apr 23 - Sun, Apr 26
DSM
Des Moines Intl.
to
CRW
Yeager
$305

roundtrip

found 6 days ago

Open DSM to CRW flights search result page
Thu, Apr 23 - Sun, Apr 26
DSM
Des Moines Intl.
to
CRW
Yeager
$318

roundtrip

found 6 days ago

Open DSM to CRW flights search result page

Route Information for Flights from Des Moines to Charleston

Origin Airport IATA Code DSM
Destination Airport IATA Code HTS
Flight Price $275
Distance 1,001 km

Des Moines to Charleston

The best fares for Des Moines to Charleston flights are always found on Orbitz. With superior discounts and the latest innovations in mobile access, your ideal trip starts with Orbitz.

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We provide access to many low-cost vacation packages and travelers can mix and match airlines when scheduling their flights for the best prices and flight times. Finding cheap tickets on flights from Des Moines to Charleston is easy when you make Orbitz your #1 travel planner.

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Our iPhone and Android mobile apps can be used to compare and book flights from Des Moines to Charleston. These apps are perfect for checking the status of flights, gate and baggage claims details, car rental rates, and for receiving alerts on special savings that are exclusive to mobile users. Mobile app users can even score great rates when booking hotel rooms. You can compare hotels, virtually view photo galleries, and check out user reviews using the app, as well as find out which ones are closest to you.

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Boost your points or miles for your frequent flyer program on certain Des Moines to Charleston flights. Simply provide your frequent flyer information when booking flights from Des Moines to Charleston with Orbitz and get both a low fare and travel rewards. You can enter this information in your Orbitz account profile for easy remembering in future bookings.

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Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

^Savings based on all package bookings with Flight + Hotel made on Orbitz.com from January 1, 2018 to December 31, 2018 as compared to the price of the same components booked separately. Savings will vary based on origin/destination, length of trip, stay dates and selected travel supplier(s). Savings not available on all packages.