$75 Cheap flight deals from Des Moines (DSM) to Anaheim (QLA)

Earn rewards on top of your airline miles with Orbitz Rewards

Many airlines offer flexible change policies

Sign up to receive text alerts about your trip

This Weekend's Flight Deals from Des Moines to Anaheim

This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sat, Jan 17 - Wed, Jan 21
DSM
Des Moines Intl.
LAX
Los Angeles Intl.
$397 Roundtrip, found 1 day ago
$397
Roundtrip
found 1 day ago
Select Delta flight, departing Sat, Jan 17 from Des Moines Intl. to Los Angeles Intl., returning Wed, Jan 21, priced at $397 found 1 day ago
Fri, Jan 16 - Mon, Jan 19
DSM
Des Moines Intl.
ONT
Los Angeles - Ontario Intl.
$607 Roundtrip, found 1 day ago
$607
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Fri, Jan 16 from Des Moines Intl. to Los Angeles - Ontario Intl., returning Mon, Jan 19, priced at $607 found 1 day ago
Sun, Jan 18 - Fri, Jan 23
DSM
Des Moines Intl.
SNA
John Wayne
$853 Roundtrip, found 1 day ago
$853
Roundtrip
found 1 day ago
Select Alaska Airlines flight, departing Sun, Jan 18 from Des Moines Intl. to John Wayne, returning Fri, Jan 23, priced at $853 found 1 day ago

Airfares from $75 One Way, $150 Round Trip from Des Moines to Anaheim

Prices starting at $150 for return flights and $75 for one-way flights to Anaheim were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sat, Mar 7 - Sat, Mar 14
DSM
Des Moines
LAX
Los Angeles
$150 Roundtrip, found 3 days ago
$150
Roundtrip
found 3 days ago
Select Frontier Airlines flight, departing Sat, Mar 7 from Des Moines to Los Angeles, returning Sat, Mar 14, priced at $150 found 3 days ago
Sat, Mar 7 - Wed, Mar 11
DSM
Des Moines
ONT
Ontario
$160 Roundtrip, found 11 hours ago
$160
Roundtrip
found 11 hours ago
Select Frontier Airlines flight, departing Sat, Mar 7 from Des Moines to Ontario, returning Wed, Mar 11, priced at $160 found 11 hours ago
Sat, Mar 28 - Fri, Apr 10
DSM
Des Moines
SNA
Orange County
$190 Roundtrip, found 1 day ago
$190
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Sat, Mar 28 from Des Moines to Orange County, returning Fri, Apr 10, priced at $190 found 1 day ago
Wed, Apr 29 - Wed, May 6
DSM
Des Moines
SNA
Orange County
$217 Roundtrip, found 4 days ago
$217
Roundtrip
found 4 days ago
Select Southwest Airlines flight, departing Wed, Apr 29 from Des Moines to Orange County, returning Wed, May 6, priced at $217 found 4 days ago
Wed, Apr 29 - Wed, May 6
DSM
Des Moines
SNA
Orange County
$217 Roundtrip, found 4 days ago
$217
Roundtrip
found 4 days ago
Select American Airlines flight, departing Wed, Apr 29 from Des Moines to Orange County, returning Wed, May 6, priced at $217 found 4 days ago

Anaheim economy flight packages

Price found within the past 48 hours. Click for updated prices.
The LEEF Hotel
2.0-star property

The LEEF Hotel

8.4/10 Very Good! (326 reviews)

Feb 26 - Mar 2

4 night stay

Des Moines (DSM) to Los Angeles (LAX)

American Airlines • Roundtrip • Coach
Price was $794, price is now $559 per person
$559
per person
found 11 hours ago
It was spotless and all new small Japanese style room and so cozy, great property and park right at your room. I already booked my next trip to LA in Jan. also very centrally located . and love the digital key that is the last 4 digit of you phone number , what a great idea!!!

Reviewed on Dec 2, 2025

Hollywood Inn Suites Hotel
2.5-star property

Hollywood Inn Suites Hotel

8.2/10 Very Good! (1,622 reviews)

Feb 26 - Mar 2

4 night stay

Des Moines (DSM) to Los Angeles (LAX)

American Airlines • Roundtrip • Coach
Save 100% on your flight
Price was $1,055, price is now $659 per person
$659
per person
found 11 hours ago
Hotel itself is clean. There was a fresh paint and sometime a strong chemical smell in the room. I was ready to find a new hotel if I could have canceled this stay. There is no coffee pot in the room, not very much space to set anything out, few drawers to put anything away. There is a coffee and flavored water machine in the lobby. The coffee is very bland, much like drinking flavor water. Overall, it’s all in the photos you just need to look closely. The room is spacious, beds are comfortable. It appears the hotel was just renovated. By the area it is located, it was most likely a pay by the hour motel in the past. At least it was clean.

Reviewed on Aug 22, 2025

Glendale Hotel
2.5-star property

Glendale Hotel

8.4/10 Very Good! (2,889 reviews)

Feb 26 - Mar 2

4 night stay

Des Moines (DSM) to Los Angeles (LAX)

American Airlines • Roundtrip • Coach
Price was $780, price is now $583 per person
$583
per person
found 11 hours ago
As a Travel RN, it is super important for me to stay in a safe, and clean hotel while I look for my permanent housing while on assignment. This hotel is darling. The rooms are super spacious, and the bed is so comfortable you do not want to get up for work. The rooms, and hotel are extremely clean, and decorated so lovely. The check in is completed virtually, and so easy. The young lady was professional, kind, and extremely helpful. There is an elevator close to the lobby to take you to your room. This hotel is located in a super safe area of Glendale, CA. It is walkable to many restaurants, coffee shops, and one of my favorite bakeries Red Ribbon. I highly recommend this hotel everyone.

Reviewed on Dec 31, 2025

Don't see what you're looking for?
See all available trips from Des Moines to Anaheim
View all trips

More About Flying To Anaheim from Des Moines

Route Information for Flights from Des Moines to Anaheim

Origin Airport IATA Code
DSM
Destination Airport IATA Code
QLA
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

Des Moines to Anaheim

Orbitz has your discount air ticket deals for flights from Des Moines to Anaheim. The guaranteed low prices from flights and hotels to car rentals and vacation packages make Orbitz the perfect travel website for budget trip planning.

Use Orbitz to Earn Frequent Flyer Miles

You know you can find great fares with Orbitz—but did you know you don’t have to give up earning miles or points towards your frequent flyer program? If you’re a member of a frequent flyer program, you can use Orbitz to find bargain prices for flights from Des Moines to Anaheim and still earn points or miles. All you have to do is add your frequent flyer account number as you book your tickets online. After you complete your travel plans, you can choose to keep your account number in your personal account profile so that you can automatically add it to your next Orbitz reservation.

Orbitz Keeps You Up-to-Date With Instant Flight Alerts

While Orbitz gives you access to cheap tickets for Des Moines to Anaheim flights, the travel site also offers free email, voice, or text message alerts to keep you informed of any abrupt changes or delays that affect your travel. You can even choose to have the alerts sent to up to six of your mobile or email contacts to keep your friends in the loop.

Bargain Des Moines to Anaheim Flights With Mobile Apps

Download the cutting-edge Orbitz app for either Android or iPhone, and use it to check on the status of your upcoming flights from Des Moines to Anaheim at any time. These apps also make it easy for you to book discount hotel rates in your destination city and check for deals on future Des Moines to Anaheim flights.

More Destinations

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.