$137 Cheap flight deals from Santo Domingo (SDQ) to Medellín (MDE)

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This Weekend's Flight Deals from Santo Domingo to Medellín

This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Fri, Oct 30 - Fri, Nov 6
SDQ
Las Americas Intl.
MDE
José María Córdova Intl.
$325 Roundtrip, found 2 hours ago
$325
Roundtrip
found 2 hours ago
Select Arajet flight, departing Fri, Oct 30 from Las Americas Intl. to José María Córdova Intl., returning Fri, Nov 6, priced at $325 found 2 hours ago

Airfares from $137 One Way, $275 Round Trip from Santo Domingo to Medellín

Prices starting at $275 for return flights and $137 for one-way flights to Medellín were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sat, Nov 21 - Fri, Nov 27
SDQ
Santo Domingo
MDE
Medellín
$275 Roundtrip, found 1 day ago
$275
Roundtrip
found 1 day ago
Select Arajet flight, departing Sat, Nov 21 from Santo Domingo to Medellín, returning Fri, Nov 27, priced at $275 found 1 day ago
Sat, Nov 21 - Fri, Nov 27
SDQ
Santo Domingo
MDE
Medellín
$280 Roundtrip, found 1 day ago
$280
Roundtrip
found 1 day ago
Select Arajet flight, departing Sat, Nov 21 from Santo Domingo to Medellín, returning Fri, Nov 27, priced at $280 found 1 day ago
Sat, Feb 27 - Sat, Mar 6
SDQ
Santo Domingo
MDE
Medellín
$281 Roundtrip, just found
$281
Roundtrip
just found
Select Arajet flight, departing Sat, Feb 27 from Santo Domingo to Medellín, returning Sat, Mar 6, priced at $281 just found
Tue, Apr 13 - Tue, Apr 20
SDQ
Santo Domingo
MDE
Medellín
$286 Roundtrip, just found
$286
Roundtrip
just found
Select Arajet flight, departing Tue, Apr 13 from Santo Domingo to Medellín, returning Tue, Apr 20, priced at $286 just found
Wed, Feb 24 - Wed, Mar 3
SDQ
Santo Domingo
MDE
Medellín
$291 Roundtrip, just found
$291
Roundtrip
just found
Select Arajet flight, departing Wed, Feb 24 from Santo Domingo to Medellín, returning Wed, Mar 3, priced at $291 just found

Medellín economy flight packages

Price found within the past 48 hours. Click for updated prices.
Golden Valley Hotel
3.0-star property

Golden Valley Hotel

9.2/10 Wonderful! (172 reviews)

Nov 22 - Nov 26

4 night stay

Santo Domingo (SDQ) to Medellín (MDE)

Sterling Blue • Roundtrip • Coach
Price was $684, price is now $417 per person
$417
per person
found 1 day ago
The staff were among the nicest I have encountered and the hotel was very clean and decently maintained. I did find some of the pictures/amenities listed a bit misrepresented. There isn't a bar available at all and the restaurant is only open for breakfast. They had irons, but no ironing board. There were no free water bottles, but they did have a water jug on the terrace. The towels were rough and tattered and they didn't have any face/wash cloths. There was absolutely no place to hang anything (hooks, racks, etc), including towels and there were not extra towels or floor mats for use for the balcony jacuzzi and even the closet was only a half closet, so I didn't have anywhere to hang a long dress. The room was small and didn't really have enough floor space even to tuck a suitcase out of the way and no drawers to unpack my stuff into.

Reviewed on Oct 22, 2026

Örök Landscape Hotel
3.5-star property

Örök Landscape Hotel

9/10 Wonderful! (20 reviews)

Dec 1 - Dec 7

6 night stay

Santo Domingo (SDQ) to Medellín (MDE)

Sterling Blue • Roundtrip • Coach
Price was $1,112, price is now $653 per person
$653
per person
found 1 day ago
David was great! All the staff was actually, it was the best get away

Reviewed on Oct 14, 2026

Hotel El Zarzo
4.0-star property

Hotel El Zarzo

9.6/10 Exceptional! (316 reviews)

Dec 11 - Dec 15

4 night stay

Santo Domingo (SDQ) to Medellín (MDE)

Sterling Blue • Roundtrip • Coach
Save 100% on your flight
Price was $840, price is now $515 per person
$515
per person
found 1 day ago
Beautiful and quiet hotel with wonderful amenities. Near but not too close to the nightlife in Provenza. Excellent breakfast and very welcoming staff.

Reviewed on Oct 22, 2026

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More About Flying To Medellín from Santo Domingo

Route Information for Flights from Santo Domingo to Medellín

Origin Airport IATA Code
SDQ
Destination Airport IATA Code
MDE
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

Santo Domingo to Medellín

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Frequently asked questions

What is the shortest flight from Santo Domingo to Medellin?
The fastest flight time from Santo Domingo to Medellin is 3 hours and 35 minutes, which gives you lots of time to enjoy a beverage or get swept up in a good movie.
What is the cheapest day of the week to fly?
Consider flying out early in the week to save on your airfare. Orbitz data from 2021 shows that Monday is the cheapest day to depart, followed by Tuesday. Saturday showed the highest average ticket prices likely because many travelers prefer to start their vacation on a weekend.
What is the cheapest month to fly?
We won't keep you guessing, according to Orbitz data from 2021, the cheapest month to fly is February. Perfect for those who need a weekend getaway, or just a break from it all in the shortest month of the year. Be aware that the most expensive time to fly is during the height of summer in July, and in the holiday month of December.*According to flight demand on Orbitz.com from January to December 2021. Savings are subject to change based on departure location, date and destination.

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Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.