$265 Cheap flight deals from St. Louis (STL) to Charleston (CRW)

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Airfares from $265 One Way, Round Trip from St. Louis to Charleston

Prices starting at for return flights and $265 for one-way flights to Charleston were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Charleston economy flight packages

Price found within the past 48 hours. Click for updated prices.
Wyndham Garden Cross Lanes Charleston
2.5-star property

Wyndham Garden Cross Lanes Charleston

7/10 Good! (1,000 reviews)

Jun 11 - Jun 15

4 night stay

St. Louis (STL) to Charleston (CRW)

American Airlines • Non-stop roundtrip • Coach
Price was $677, price is now $604 per person
$604
per person
found 1 day ago
Much construction/renovation happening. Property should be really nice in the future.

Reviewed on Sep 21, 2025

Hampton Inn Charleston-Southridge
2.5-star property

Hampton Inn Charleston-Southridge

9.4/10 Exceptional! (1,003 reviews)

Jun 11 - Jun 15

4 night stay

St. Louis (STL) to Charleston (CRW)

American Airlines • Non-stop roundtrip • Coach
Price was $862, price is now $723 per person
$723
per person
found 1 day ago
Great pool for our kids. Clean.

Reviewed on Jan 6, 2026

Holiday Inn Express Charleston-Civic Center by IHG
2.5-star property

Holiday Inn Express Charleston-Civic Center by IHG

8.6/10 Excellent! (1,168 reviews)

Jun 11 - Jun 15

4 night stay

St. Louis (STL) to Charleston (CRW)

American Airlines • Non-stop roundtrip • Coach
Price was $681, price is now $623 per person
$623
per person
found 1 day ago
Very comfortable bed, very clean and quiet

Reviewed on Nov 17, 2025

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More About Flying To Charleston from St. Louis

Route Information for Flights from St. Louis to Charleston

Origin Airport IATA Code
STL
Destination Airport IATA Code
CRW
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

St. Louis to Charleston

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Orbitz looks for the best deals on St. Louis to Charleston flights for you. Mix and match airlines for your departing and return flights to fit your travel schedule and budget.

Frequently asked questions

What is the shortest flight from St. Louis to Charleston?
The journey from St. Louis to Charleston can be as fast as 2 hours and 40 minutes. With a short and sweet flight time like this, why not take off on a spontaneous getaway?
What is the cheapest day of the week to fly?
Consider flying out early in the week to save on your airfare. Orbitz data from 2021 shows that Monday is the cheapest day to depart, followed by Tuesday. Saturday showed the highest average ticket prices likely because many travelers prefer to start their vacation on a weekend.
What is the cheapest month to fly?
We won't keep you guessing, according to Orbitz data from 2021, the cheapest month to fly is February. Perfect for those who need a weekend getaway, or just a break from it all in the shortest month of the year. Be aware that the most expensive time to fly is during the height of summer in July, and in the holiday month of December.*According to flight demand on Orbitz.com from January to December 2021. Savings are subject to change based on departure location, date and destination.

More Destinations

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.