$123 Cheap flight deals from St. Louis (STL) to James Island (CHS)

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This Weekend's Flight Deals from St. Louis to James Island

This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Fri, Apr 3 - Sun, Apr 5
STL
Lambert-St. Louis Intl.
CHS
Charleston Intl.
$364 Roundtrip, found 2 days ago
$364
Roundtrip
found 2 days ago
Select American Airlines flight, departing Fri, Apr 3 from Lambert-St. Louis Intl. to Charleston Intl., returning Sun, Apr 5, priced at $364 found 2 days ago

Airfares from $123 One Way, $259 Round Trip from St. Louis to James Island

Prices starting at $259 for return flights and $123 for one-way flights to James Island were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Wed, May 6 - Sat, May 9
STL
St. Louis
CHS
Charleston
$259 Roundtrip, found 3 days ago
$259
Roundtrip
found 3 days ago
Select Southwest Airlines flight, departing Wed, May 6 from St. Louis to Charleston, returning Sat, May 9, priced at $259 found 3 days ago
Thu, May 28 - Tue, Jun 2
STL
St. Louis
CHS
Charleston
$262 Roundtrip, found 15 hours ago
$262
Roundtrip
found 15 hours ago
Select Delta flight, departing Thu, May 28 from St. Louis to Charleston, returning Tue, Jun 2, priced at $262 found 15 hours ago
Wed, May 6 - Sat, May 9
STL
St. Louis
CHS
Charleston
$265 Roundtrip, found 3 days ago
$265
Roundtrip
found 3 days ago
Select United flight, departing Wed, May 6 from St. Louis to Charleston, returning Sat, May 9, priced at $265 found 3 days ago
Wed, May 20 - Sat, May 23
STL
St. Louis
CHS
Charleston
$269 Roundtrip, found 2 days ago
$269
Roundtrip
found 2 days ago
Select American Airlines flight, departing Wed, May 20 from St. Louis to Charleston, returning Sat, May 23, priced at $269 found 2 days ago
Wed, May 6 - Sat, May 9
STL
St. Louis
CHS
Charleston
$274 Roundtrip, found 3 days ago
$274
Roundtrip
found 3 days ago
Select Delta flight, departing Wed, May 6 from St. Louis to Charleston, returning Sat, May 9, priced at $274 found 3 days ago

James Island economy flight packages

Price found within the past 48 hours. Click for updated prices.
Wild Dunes Resort – Sweetgrass Inn and Boardwalk Inn
4.0-star property

Wild Dunes Resort – Sweetgrass Inn and Boardwalk Inn

8.8/10 Excellent! (1,003 reviews)

May 7 - May 11

4 night stay

St. Louis (STL) to Charleston (CHS)

Southwest Airlines • Roundtrip • Coach
Price was $1,369, price is now $1,076 per person
$1,076
per person
found 10 hours ago
It is a convenient layout with restaurants, pools, bars as well as the beach safe for the grandchildren.

Reviewed on Sep 3, 2025

The Beach Club at Charleston Harbor Resort and Marina
4.5-star property

The Beach Club at Charleston Harbor Resort and Marina

9.2/10 Wonderful! (1,000 reviews)

May 7 - May 11

4 night stay

St. Louis (STL) to Charleston (CHS)

Southwest Airlines • Roundtrip • Coach
Save 100% on your flight
Price was $1,822, price is now $1,440 per person
$1,440
per person
found 10 hours ago
Very nice rooms and restaurant on property. Pool, hot tub, beach... nice place.

Reviewed on Nov 14, 2024

Andrew Pinckney Inn
4.0-star property

Andrew Pinckney Inn

9.6/10 Exceptional! (1,472 reviews)

May 21 - May 24

3 night stay

St. Louis (STL) to Charleston (CHS)

Southwest Airlines • Coach

Charleston (CHS) to St. Louis (STL)

American Airlines • Coach
Price was $1,578, price is now $1,273 per person
$1,273
per person
found 8 hours ago
The staff were pleasant and helpful. The location was fantastic for parking, walking and enjoying the City. The rooms were clean and nice. The happy hour wine and cheese were the icing on the cake!! You will love it.

Reviewed on Jan 30, 2026

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More About Flying To James Island from St. Louis

Route Information for Flights from St. Louis to James Island

Origin Airport IATA Code
STL
Destination Airport IATA Code
CHS
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

St. Louis to James Island

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Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.