
$273 Cheap flight deals from San Antonio (SAT) to Medellín (MDE)
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This Weekend's Flight Deals from San Antonio to Medellín
This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Airfares from $273 One Way, $685 Round Trip from San Antonio to Medellín
Prices starting at $685 for return flights and $273 for one-way flights to Medellín were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Medellín economy flight packages

The Charlee Hotel
Jun 24 - Jun 29
San Antonio (SAT) to Medellín (MDE)
Reviewed on Apr 28, 2026


More About Flying To Medellín from San Antonio
Route Information for Flights from San Antonio to Medellín
Origin Airport IATA Code | SAT |
|---|---|
Destination Airport IATA Code | MDE |
Distance | |
Direct Flight Airlines | |
Earliest Flight Arrival | |
Latest Flight Arrival |
San Antonio to Medellín
When you’re ready to take your next trip, get the most affordable prices on flights from San Antonio to Medellín with Orbitz! The guaranteed low prices and cutting-edge mobile tools on Orbits make it easy for you to plan your next great vacation.
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As any traveler knows, air travel can suddenly be temporarily halted due to service disruptions. Along with offering the best fares for flights from San Antonio to Medellín, Orbitz also offers free mobile phone and email alerts that help you keep up with sudden changes to your flight plans. Choose from email, text, or voice message alerts.
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Frequently asked questions
Flights to Medellín
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Flights from San Antonio
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San Antonio Airports
Medellín Airports
More Destinations
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- Amaga Hotels
- Apartments in Bello
- Farmstay in Retiro
- Retiro Hotels
- Hotels near Hospital Universitario San Vicente de Paul
- Hotels near Medellín Clinic - El Poblado
- Hotels near Atanasio Giradot Stadium
- Cabin Rentals in Rionegro
- Rionegro Hotels
- Villas in Rionegro
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- Business Hotels in Antioquia
- Kid Friendly Hotels in Antioquia
- Hotels with Hot Tubs in Antioquia
- Pet Friendly Hotels in Antioquia
- Spa Resorts & in Antioquia
- Hotels with a Wedding Venue in Antioquia
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- Villas in San Jerónimo
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- Extended Stay Hotels in Itagüí
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- Hotels near Lleras Park
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- Flights from New York (JFK) to Medellín (MDE)
- Flights from Los Angeles (LAX) to Medellín (MDE)
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- Flights to Antioquia
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- Flights from Minneapolis - St. Paul to Guatapé
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- Car rental Rionegro
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- Budget Rental Cars in José María Córdova Intl.
- Dollar Rent A Car Rental Cars in José María Córdova Intl.
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- Hertz Rental Cars in José María Córdova Intl.
- Payless Rental Cars in José María Córdova Intl.
- Car rentals near Antioquia
- Car rental Sabaneta
Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.


