
$110 Cheap flight deals from Boston (BOS) to Vandalia (STL)
Earn rewards on top of your airline miles with Orbitz Rewards
Many airlines offer flexible change policies
Sign up to receive text alerts about your trip
This Weekend's Flight Deals from Boston to Vandalia
This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Airfares from $110 One Way, $265 Round Trip from Boston to Vandalia
Prices starting at $265 for return flights and $110 for one-way flights to Vandalia were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Vandalia economy flight packages

Motel 6 Rolla, MO
Aug 14 - Aug 19
Boston (BOS) to St. Louis (STL)
Reviewed on Mar 1, 2023


Hilton Pennywell St. Louis at the Arch
Jul 31 - Aug 3
Boston (BOS) to St. Louis (STL)
Reviewed on May 11, 2026
More About Flying To Vandalia from Boston
Route Information for Flights from Boston to Vandalia
Origin Airport IATA Code | BOS |
|---|---|
Destination Airport IATA Code | STL |
Distance | |
Direct Flight Airlines | |
Earliest Flight Arrival | |
Latest Flight Arrival |
Boston to Vandalia
Orbitz has your best deals on Boston to Vandalia flights. From guaranteed low prices to cutting-edge mobile tools, the perfect trip begins on Orbitz.
Get Orbitz On the Go for Flights from Boston to Vandalia
Use our mobile apps for Android and iPhone to find the best price on flights from Boston to Vandalia. Check your flight status, gate and baggage claim details, and book exclusive mobile deals on hotels — even on the same day.
Rack Up Miles While Flying for Cheaper
Earn miles or points toward your frequent flyer program on select Boston to Vandalia flights. When you book your flight on Orbitz, simply add your qualifying frequent flyer number where prompted. You can also store your airline frequent flyer or loyalty program numbers in your Orbitz account profile to automatically add them to your future reservations.
Worry Less With Flight Alerts
Orbitz is the best source for booking flights from Boston to Vandalia. But we also keep you updated about flight delays, booking changes, or service disruptions with free alerts. Get alerts on Boston to Vandalia flights sent to your email or via voice or text to your mobile phone. We can also send the alerts to up to 6 other email addresses or phone numbers, which is helpful if you are being picked up at the airport.
Budget Travel Planning Made Easy
It's easy to find discount air tickets for flights from Boston to Vandalia on Orbitz. Mix and match airlines for your departing and your returning flights to find the lowest fares and the best schedule.
Flights from Boston
- Boston to Orlando
- Boston to Los Angeles
- Boston to Chicago
- Boston to London
- Boston to New York
- Boston to Miami
- Boston to Paris
- Boston to Atlanta
- Boston to Toronto
- Boston to Houston
- Boston to Dallas
- Boston to Rome
- Boston to Madrid
- Boston to Montreal
- Boston to Detroit
- Boston to Buenos Aires
- Boston to São Paulo
- Boston to Beijing
- Boston to Kansas City
- Boston to Berlin
Vandalia Airports
More Destinations
- Flights from Atlanta to Greenville
- Flights from Charlotte to Greenville
- Flights from Chicago to Greenville
- Flights from Columbus to Greenville
- Flights from Dallas to Greenville
- Flights from Houston to Greenville
- Flights from Kansas City to Greenville
- Flights from Las Vegas to Greenville
- Flights from Memphis to Greenville
- Flights from Nashville to Greenville
- Flights from Phoenix to Greenville
- Flights from Portland to Greenville
- Flights from Salt Lake City to Greenville
- Flights from Charleston to Greenville
- Flights from Palm Springs to Greenville
- Flights from Monroe to Greenville
- Flights from Omaha to Greenville
- Flights from Billings to Greenville
- Flights from Syracuse to Greenville
- Flights from Daytona Beach to Greenville
- Flights from Buffalo to Greenville
- Flights from Shreveport to Greenville
- Flights from Spokane to Greenville
- Flights from Greensboro to Greenville
- Flights from Birmingham to Greenville
- Flights from Huntsville to Greenville
- Flights from Grand Rapids to Greenville
- Flights from Augusta to Greenville
- Flights from Greenville - Spartanburg to Greenville
- Flights from Bangor to Greenville
- Flights from Aberdeen to Greenville
- Flights from Dallas to Charleston
- Flights from Mexico City to Charleston
- Flights from Minneapolis - St. Paul to Charleston
- Flights from Huntsville to Charleston
- Flights from Hyderabad to Charleston
- Flights from State College to Charleston
- Flights from Wausau to Charleston
- Flights from Grand Canyon to Charleston
- Flights from Green Bay to Grafton
- Flights from Detroit to Grafton
- Flights from Miami to Grafton
- Flights from Minneapolis - St. Paul to Grafton
- Flights from Milwaukee to Grafton
- Flights from Shreveport to Grafton
- Flights from Tampa to Grafton
- Flights from Biloxi to Grafton
- Flights from Rapid City to Grafton
- Flights from Sioux Falls to Grafton
- Flights from Salt Lake City to Mascoutah
- Flights from Manchester to Alton
- Flights from Boston to Southern Illinois
- Flights from Minneapolis - St. Paul to Southern Illinois
- Flights from Fairbanks to Mattoon
- Flights from Guadalajara to Mattoon
- Flights from Durango to Mattoon
- Flights from Waterloo to Mattoon
- Flights from Pensacola to Mattoon
- Flights from Buffalo to Mattoon
- Flights from Sarasota to Mattoon
- Flights from Newport News to Mattoon
- Flights from Edinburgh to Mattoon
- Flights from College Station to Mattoon
- Flights from El Paso to Belleville
- Flights from Florence to Belleville
- Flights from Grand Junction to Belleville
- Flights from Anchorage to Belleville
- Flights from Bogotá to Belleville
- Flights from Charlotte to Belleville
- Flights from Lima to Belleville
- Flights from Minneapolis - St. Paul to Belleville
- Flights from Portland to Belleville
- Flights from San Francisco to Belleville
- Flights from Cancun to Belleville
- Flights from St. Petersburg to Belleville
- Flights from Sacramento to Belleville
- Flights from Jacksonville to Belleville
- Flights from St. George to Belleville
- Flights from Bakersfield to Belleville
- Flights from Hilton Head Island to Belleville
- Flights from Newburgh to Belleville
- Flights from Bloomington to Belleville
- Flights from Shreveport to Belleville
- Flights from Spokane to Belleville
- Flights from Dayton to Belleville
- Flights from Huntsville to Belleville
- Flights from Tucson to Belleville
- Flights from Tampa to Belleville
- Flights from Boise to Belleville
- Flights from Binghamton to Belleville
- Flights from Fayetteville to Belleville
- Flights from Bangor to Belleville
- Flights from Newport News to Belleville
- Flights from State College to Belleville
- Flights from Fort Smith to Belleville
- Flights from Fargo to Belleville
- Flights from Covington to Belleville
- Flights from Sioux Falls to Belleville
- Flights from Amsterdam to O'Fallon
- Flights from Sao Paulo to O'Fallon
Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.


