Many airlines offer flexible change policies
Sign up to receive text alerts about your trip
Prices starting at $539 for return flights and $254 for one-way flights to San Francisco were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
|Origin Airport IATA Code||EYW|
|Destination Airport IATA Code||SJC|
|Direct Flight Airlines|
|Earliest Flight Arrival|
|Latest Flight Arrival|
Orbitz On-the-Go is your one-stop shop for discount vacation air travel. Our cutting-edge mobile tools leave you time to pack for the trip. Shop our sales on domestic flights from Key West to San Francisco.
Cheap vacations start at Orbitz On-the-Go. Find the best deals on international flights from Key West to San Francisco.
Your phone becomes a full-service vacation travel agency with Orbitz mobile phone apps. From reservations to arrivals, every detail is in the palm of your hand. Book budget flights from Key West to San Francisco; add a car and hotel, share your itinerary and keep up with changes. Orbitz apps cover all the bases for you.
Free Alerts from Orbitz On-the-Go keep your vacation free from worry. Free Alerts updates you the moment any changes occur. You’ll always have the most current flight, gate and baggage claim details. So sit back and enjoy your low fare on Key West to San Francisco flights.
Orbitz On-the-Go securely stores your frequent flier and loyalty program information. Watch your miles add up when you book discount Key West to San Francisco flights with Orbitz. Make your vacation mileage-friendly with low cost air tickets on Key West to San Francisco flights. Orbitz is your destination for vacation value.
Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.