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Fares from $188 One Way, $419 Round Trip from Key West to San Francisco

Prices starting at $419 for return flights and $188 for one-way flights to San Francisco were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

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More About Flying To San Francisco from Key West

Route Information for Flights from Key West to San Francisco

Origin Airport IATA CodeEYW
Destination Airport IATA CodeSJC
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

Key West to San Francisco

Orbitz assures that you will receive cheap air fares on flights from Key West to San Francisco and special deals that give you guaranteed low prices on hotels, cruises, car rentals, and anything else you need on your trip.

Free Orbitz mobile app for your Android or iPad

Get the latest Orbitz app for your smartphone and tablet to book low cost cars, hotels, and Key West to San Francisco flights. Our cutting-edge mobile tools let you view your trip itinerary on your mobile device anytime you need it. You can research great deals on highly rated hotels near you with the app, which uses your smartphone’s GPS, and book the one you like with just a few taps.

Orbitz mobile site for even more convenience

Use your mobile Web browser to get savings on flights from Key West to San Francisco. Our mobile site, m.orbitz.com, offers the same powerful search and other capabilities you expect from our regular site. Retrieve and share your itinerary for your from Key West to San Francisco flights with friends, family members, and colleagues, and browse photo galleries and user reviews of hotels to find the one you like.

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Receive free, real-time updates on your low fare flights from Key West to San Francisco via your mobile phone or email inbox. Stay on top of delays, gate charges, and other event notifications so you can make other travel arrangements if you need to.

Low fares on Key West to San Francisco flights

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Flights from Key West to San Francisco - Frequently Asked Questions

Are there non-stop flights from Key West to San Francisco?

As you can't fly directly from Key West, FL (EYW-Key West Intl.) to San Francisco, CA (SFO-San Francisco Intl.), a flight with one stopover is your next best option. American Airlines, United Airlines and Delta Air Lines are reputable airlines that service this route.

What is the shortest flight from Key West to San Francisco?

The shortest flight from Key West, FL (EYW-Key West Intl.) to San Francisco, CA (SFO-San Francisco Intl.) is 6 hours and 30 minutes. Slip a few things into your carry-on to keep you occupied, like a magazine or some playing cards.

If I am not able to travel due to COVID-19, can I cancel my flight to San Francisco?

We get that traveling right now has its challenges, so it's good to know that many reservations booked through us are able to be cancelled or changed. If your travel plans to San Francisco have been affected by COVID-19, a lot of airlines are making things easier by offering credits to use at a later date. Just sign in to your account and you'll quickly see what options are available. Our Customer Service Portal is the place to go for more information.

Are there flights to San Francisco with flexible change policies?

In most cases you'll have the option to reschedule your flight to San Francisco without a change fee. All you have to do then is pay the difference between the old flight and the new one. Look for the "no change fees" filter and book with confidence.

What is the cheapest day of the week to fly?

Consider flying out early in the week to save on your airfare. Orbitz data from 2019 shows that Tuesday is the cheapest day to depart, followed by Monday. Saturday showed the highest average ticket prices likely because many travelers prefer to start their vacation on a weekend.

What is the cheapest month to fly?

We won't keep you guessing, according to Orbitz data the cheapest month to fly is February. Perfect for those who need a weekend getaway, or just a fresh start to the new year. Be aware that the most expensive time to fly isn't the height of summer, as most people assume, but the festive month of December.

How can I save money on flights?

To really save big on your next vacation, think outside the box. Select two different airlines or fare types for your return trip and you'll generally get a much better deal. Those who tried this on Orbitz in 2019 saved over 50% on their airfares. Get mixing and matching today!

*According to flight demand on Orbitz.com from January to December 2019. Savings are subject to change based on departure location, date and destination.

^Savings based on all package bookings with Flight + Hotel made on Orbitz.com from January 1, 2019 to December 31, 2019 as compared to the price of the same components booked separately. Savings will vary based on origin/destination, length of trip, stay dates and selected travel supplier(s). Savings not available on all packages.