Cheap flights from COU to SNA (Columbia Regional to John Wayne)

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Cheap Flights from COU to SNA starting at $350 One Way, $613 Round Trip

Prices starting at $613 for return flights and $350 for one-way flights to John Wayne were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Tue, May 26 - Tue, Aug 18
COU
Columbia
SNA
Orange County
$613 Roundtrip, found 4 days ago
$613
Roundtrip
found 4 days ago
Select United flight, departing Tue, May 26 from Columbia to Orange County, returning Tue, Aug 18, priced at $613 found 4 days ago
Tue, May 26 - Tue, Aug 18
COU
Columbia
SNA
Orange County
$617 Roundtrip, found 4 days ago
$617
Roundtrip
found 4 days ago
Select United flight, departing Tue, May 26 from Columbia to Orange County, returning Tue, Aug 18, priced at $617 found 4 days ago
Tue, May 26 - Tue, Aug 18
COU
Columbia
SNA
Orange County
$639 Roundtrip, found 4 days ago
$639
Roundtrip
found 4 days ago
Select United flight, departing Tue, May 26 from Columbia to Orange County, returning Tue, Aug 18, priced at $639 found 4 days ago
Tue, May 26 - Tue, Aug 18
COU
Columbia
SNA
Orange County
$642 Roundtrip, found 4 days ago
$642
Roundtrip
found 4 days ago
Select United flight, departing Tue, May 26 from Columbia to Orange County, returning Tue, Aug 18, priced at $642 found 4 days ago
Tue, May 26 - Tue, Aug 18
COU
Columbia
SNA
Orange County
$644 Roundtrip, found 4 days ago
$644
Roundtrip
found 4 days ago
Select United flight, departing Tue, May 26 from Columbia to Orange County, returning Tue, Aug 18, priced at $644 found 4 days ago

Hotel Ideas near John Wayne

Airport Hotels near John Wayne

Ayres Hotel Costa Mesa/Newport Beach

Ayres Hotel Costa Mesa/Newport Beach

4 out of 5
325 Bristol Street Costa Mesa CA
$139 nightly
The price is $155 total per night from Apr 1 to Apr 2
$155 total
Apr 1 - Apr 2
Total with taxes and fees
Book a stay at this business-friendly hotel in Costa Mesa. Enjoy free WiFi, 2 outdoor pools, and a free airport shuttle. Our guests praise the breakfast and ...
9/10 Wonderful! (3,151 reviews)
This was a cute hotel it had a comfortable setting and was quiet. It was definitely overpriced. I would have stayed longer. If it wasn’t the price that I had paid. Staff was nice. The parking was unreasonable at $25 a night per vehicle when we had three cars other than that it was a nice place.

Reviewed on Mar 28, 2026

Ayres Hotel Costa Mesa/Newport Beach
Embassy Suites by Hilton Santa Ana Orange County Airport

Embassy Suites by Hilton Santa Ana Orange County Airport

3.5 out of 5
1325 East Dyer Road Santa Ana CA
$122 nightly
The price is $138 total per night from Apr 5 to Apr 6
$138 total
Apr 5 - Apr 6
Total with taxes and fees
Book a stay at this business-friendly hotel in Santa Ana. Enjoy free breakfast, a free airport shuttle, and room service. Our guests praise the breakfast and ...
6.2/10 (1,944 reviews)
Breakfast menu was fresh. Front desk was very helpful. Room I was assigned to, Tv and phone did not work. When ask to move rooms there was no fuss! Balcony view ended up being in front of the building units. Housekeeping was attending every other day not every day.

Reviewed on Mar 28, 2026

Embassy Suites by Hilton Santa Ana Orange County Airport
MainStay Suites John Wayne Airport by Choice Hotels

MainStay Suites John Wayne Airport by Choice Hotels

2.5 out of 5
2701 Hotel Terrace Santa Ana CA
$93 nightly
The price is $105 total per night from Apr 5 to Apr 6
$105 total
Apr 5 - Apr 6
Total with taxes and fees
Book a stay at this business-friendly hotel in Santa Ana. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8/10 Very Good! (1,735 reviews)
It was clean.

Reviewed on Mar 28, 2026

MainStay Suites John Wayne Airport by Choice Hotels
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In Orange County

Holiday Inn Santa Ana-Orange Co. Arpt by IHG

Holiday Inn Santa Ana-Orange Co. Arpt by IHG

3 out of 5
2726 S Grand Ave Santa Ana CA
$125 nightly
The price is $142 total per night from Apr 5 to Apr 6
$142 total
Apr 5 - Apr 6
Total with taxes and fees
Book a stay at this business-friendly hotel in Santa Ana. Enjoy free WiFi, a fitness center, and parking (surcharge). Our guests praise the helpful staff and ...
8.8/10 Excellent! (1,294 reviews)
More or less great place to stay except the front desk staff are way too busy to acknowledge or talk to you, all the time. And no water bottles in the rooms. I can’t imagine why not. Everything else was pretty good including the breakfast and room service. They could use some newer towels since the ...

Reviewed on Mar 28, 2026

Holiday Inn Santa Ana-Orange Co. Arpt by IHG
Embassy Suites by Hilton Santa Ana Orange County Airport

Embassy Suites by Hilton Santa Ana Orange County Airport

3.5 out of 5
1325 East Dyer Road Santa Ana CA
$122 nightly
The price is $138 total per night from Apr 5 to Apr 6
$138 total
Apr 5 - Apr 6
Total with taxes and fees
Book a stay at this business-friendly hotel in Santa Ana. Enjoy free breakfast, a free airport shuttle, and room service. Our guests praise the breakfast and ...
6.2/10 (1,944 reviews)
Breakfast menu was fresh. Front desk was very helpful. Room I was assigned to, Tv and phone did not work. When ask to move rooms there was no fuss! Balcony view ended up being in front of the building units. Housekeeping was attending every other day not every day.

Reviewed on Mar 28, 2026

Embassy Suites by Hilton Santa Ana Orange County Airport
MainStay Suites John Wayne Airport by Choice Hotels

MainStay Suites John Wayne Airport by Choice Hotels

2.5 out of 5
2701 Hotel Terrace Santa Ana CA
$93 nightly
The price is $105 total per night from Apr 5 to Apr 6
$105 total
Apr 5 - Apr 6
Total with taxes and fees
Book a stay at this business-friendly hotel in Santa Ana. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8/10 Very Good! (1,735 reviews)
It was clean.

Reviewed on Mar 28, 2026

MainStay Suites John Wayne Airport by Choice Hotels
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Orange County Hotels With Airport Transportation

MainStay Suites John Wayne Airport by Choice Hotels

MainStay Suites John Wayne Airport by Choice Hotels

2.5 out of 5
2701 Hotel Terrace Santa Ana CA
$93 nightly
The price is $105 total per night from Apr 5 to Apr 6
$105 total
Apr 5 - Apr 6
Total with taxes and fees
Book a stay at this business-friendly hotel in Santa Ana. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8/10 Very Good! (1,735 reviews)
It was clean.

Reviewed on Mar 28, 2026

MainStay Suites John Wayne Airport by Choice Hotels
Best Western Plus Orange County Airport North

Best Western Plus Orange County Airport North

2.5 out of 5
2700 Hotel Terrace Dr. Santa Ana CA
$113 nightly
The price is $128 total per night from Mar 29 to Mar 30
$128 total
Mar 29 - Mar 30
Total with taxes and fees
Book a stay at this business-friendly hotel in Santa Ana. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.6/10 Excellent! (1,792 reviews)
My place when im out there on corporate meeting or events

Reviewed on Mar 27, 2026

Best Western Plus Orange County Airport North
Hotel Zessa Orange County Airport, a DoubleTree by Hilton

Hotel Zessa Orange County Airport, a DoubleTree by Hilton

4 out of 5
201 E MacArthur Blvd Santa Ana CA
$114 nightly
The price is $129 total per night from Apr 4 to Apr 5
$129 total
Apr 4 - Apr 5
Total with taxes and fees
Book a stay at this business-friendly hotel in Santa Ana. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful staff ...
9/10 Wonderful! (678 reviews)
Lobby was modern, very clean and open. Gym room was beautiful and clean. Hotel Room could’ve been more modern but was clean. Parking was very easy and close to get to. Staff was very accommodating.

Reviewed on Mar 22, 2026

Hotel Zessa Orange County Airport, a DoubleTree by Hilton
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced Orange County Hotels

Motel 6 Santa Ana, CA

Motel 6 Santa Ana, CA

2 out of 5
1623 East 1st Street Santa Ana CA
$79 nightly
The price is $89 total per night from Mar 31 to Apr 1
$89 total
Mar 31 - Apr 1
Total with taxes and fees
Stay at this motel in Santa Ana. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7.4/10 Good! (1,000 reviews)
.

Reviewed on Mar 26, 2026

Motel 6 Santa Ana, CA
West Coast Inn - Near Gem Theatre

West Coast Inn - Near Gem Theatre

2 out of 5
Santa Ana CA
$104 nightly
The price is $115 total per night from Mar 29 to Mar 30
$115 total
Mar 29 - Mar 30
Total with taxes and fees
Stay at this vacation home in Santa Ana. Enjoy free WiFi, free parking, and room service. Popular attractions Anaheim Convention Center and Disney California ...
7/10 Good! (317 reviews)
Spent too much money for a jacuzzi room. Jacuzzi broken, no television, chick on drugs knocking on my window all night, what a treat.

Reviewed on Mar 21, 2026

West Coast Inn - Near Gem Theatre
Best Western Plus Orange County Airport North

Best Western Plus Orange County Airport North

2.5 out of 5
2700 Hotel Terrace Dr. Santa Ana CA
$113 nightly
The price is $128 total per night from Mar 29 to Mar 30
$128 total
Mar 29 - Mar 30
Total with taxes and fees
Book a stay at this business-friendly hotel in Santa Ana. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.6/10 Excellent! (1,792 reviews)
My place when im out there on corporate meeting or events

Reviewed on Mar 27, 2026

Best Western Plus Orange County Airport North
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Orange County

Embassy Suites by Hilton Santa Ana Orange County Airport

Embassy Suites by Hilton Santa Ana Orange County Airport

3.5 out of 5
1325 East Dyer Road Santa Ana CA
$122 nightly
The price is $138 total per night from Apr 5 to Apr 6
$138 total
Apr 5 - Apr 6
Total with taxes and fees
Book a stay at this business-friendly hotel in Santa Ana. Enjoy free breakfast, a free airport shuttle, and room service. Our guests praise the breakfast and ...
6.2/10 (1,944 reviews)
Breakfast menu was fresh. Front desk was very helpful. Room I was assigned to, Tv and phone did not work. When ask to move rooms there was no fuss! Balcony view ended up being in front of the building units. Housekeeping was attending every other day not every day.

Reviewed on Mar 28, 2026

Embassy Suites by Hilton Santa Ana Orange County Airport
MainStay Suites John Wayne Airport by Choice Hotels

MainStay Suites John Wayne Airport by Choice Hotels

2.5 out of 5
2701 Hotel Terrace Santa Ana CA
$93 nightly
The price is $105 total per night from Apr 5 to Apr 6
$105 total
Apr 5 - Apr 6
Total with taxes and fees
Book a stay at this business-friendly hotel in Santa Ana. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8/10 Very Good! (1,735 reviews)
It was clean.

Reviewed on Mar 28, 2026

MainStay Suites John Wayne Airport by Choice Hotels
Best Western Plus Orange County Airport North

Best Western Plus Orange County Airport North

2.5 out of 5
2700 Hotel Terrace Dr. Santa Ana CA
$113 nightly
The price is $128 total per night from Mar 29 to Mar 30
$128 total
Mar 29 - Mar 30
Total with taxes and fees
Book a stay at this business-friendly hotel in Santa Ana. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.6/10 Excellent! (1,792 reviews)
My place when im out there on corporate meeting or events

Reviewed on Mar 27, 2026

Best Western Plus Orange County Airport North
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

COU to SNA Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date
COU Address & GPS
Address:
Route 1
Columbia MO, 65201
United States
IATA Code:
COU
Longitude:
-92.219167
Latitude:
38.813611
Time Zone:
America/Chicago
SNA Address & GPS
Address:
18601 Airport Way
Santa Ana CA, 92707
United States
IATA Code:
SNA
Longitude:
-117.860538
Latitude:
33.680201
Time Zone:
America/Los_Angeles

Frequently asked questions

Are there non-stop flights from COU to John Wayne Airport (SNA)?
While you can't fly direct from COU to John Wayne Airport (SNA), there are plenty of airlines that service this route with just a single stopover. Why not see if the dates available with American Airlines or Qatar Airways match your travel plans? If not, take a look at Qantas.
What is the shortest flight from Columbia Regional Airport to John Wayne Airport?
The shortest flight from Columbia to Santa Ana is 5 hours and 36 minutes. Grab a refreshment from the cabin crew, start your travel journal or get to know your neighbors — you'll have the time on this medium-haul trip.
How many hours flight from COU to John Wayne Airport (SNA)?
It typically takes about 5 hours and 44 minutes to jet from Columbia Regional Airport (COU) to John Wayne Airport. You'll be in the air for a good amount of time, so contemplate bringing some entertainment, like a good read or a few podcasts.
What airlines have the most flights from Columbia Regional Airport (COU) to SNA?
You won't find any airlines flying direct between Columbia Regional Airport and John Wayne Airport (SNA). Do your research and secure a multi or single-stop plane ticket.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

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