$56 Cheap flight deals from Daytona Beach (DAB) to Knoxville (DSM)

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This Weekend's Flight Deals from Daytona Beach to Knoxville

This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sun, Dec 28 - Sat, Jan 3
MCO
Orlando Intl.
DSM
Des Moines Intl.
$227 Roundtrip, found 3 days ago
$227
Roundtrip
found 3 days ago
Select Frontier Airlines flight, departing Sun, Dec 28 from Orlando Intl. to Des Moines Intl., returning Sat, Jan 3, priced at $227 found 3 days ago
Sun, Dec 28 - Thu, Jan 1
JAX
Jacksonville Intl.
DSM
Des Moines Intl.
$605 Roundtrip, found 6 days ago
$605
Roundtrip
found 6 days ago
Select American Airlines flight, departing Sun, Dec 28 from Jacksonville Intl. to Des Moines Intl., returning Thu, Jan 1, priced at $605 found 6 days ago

Airfares from $56 One Way, $100 Round Trip from Daytona Beach to Knoxville

Prices starting at $100 for return flights and $56 for one-way flights to Knoxville were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Thu, Mar 12 - Sat, Mar 21
MCO
Orlando
DSM
Des Moines
$100 Roundtrip, found 4 days ago
$100
Roundtrip
found 4 days ago
Select Frontier Airlines flight, departing Thu, Mar 12 from Orlando to Des Moines, returning Sat, Mar 21, priced at $100 found 4 days ago
Wed, Feb 25 - Tue, Mar 10
MCO
Orlando
DSM
Des Moines
$164 Roundtrip, found 1 day ago
$164
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Wed, Feb 25 from Orlando to Des Moines, returning Tue, Mar 10, priced at $164 found 1 day ago
Wed, Feb 25 - Mon, Mar 9
MCO
Orlando
DSM
Des Moines
$174 Roundtrip, found 1 day ago
$174
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Wed, Feb 25 from Orlando to Des Moines, returning Mon, Mar 9, priced at $174 found 1 day ago
Sat, Mar 14 - Fri, Mar 20
MCO
Orlando
DSM
Des Moines
$178 Roundtrip, found 2 days ago
$178
Roundtrip
found 2 days ago
Select Frontier Airlines flight, departing Sat, Mar 14 from Orlando to Des Moines, returning Fri, Mar 20, priced at $178 found 2 days ago
Mon, Feb 23 - Tue, Mar 10
MCO
Orlando
DSM
Des Moines
$191 Roundtrip, found 1 day ago
$191
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Mon, Feb 23 from Orlando to Des Moines, returning Tue, Mar 10, priced at $191 found 1 day ago

Knoxville economy flight packages

Price found within the past 48 hours. Click for updated prices.
Holiday Inn Downtown - Mercy Area by IHG
3.0-star property

Holiday Inn Downtown - Mercy Area by IHG

8/10 Very Good! (1,001 reviews)

Feb 19 - Feb 23

4 night stay

Jacksonville (JAX) to Des Moines (DSM)

Southwest Airlines • Non-stop roundtrip • Coach
Price was $703, price is now $588 per person
$588
per person
found 1 day ago
Stayed here for Paul McCartney concert. Parking lot was under construction so we had to park at the hospital. Lounge was never open even though they were full and would have had lots of customers. Staff seemed flustered by the crowd returning from the concert as elevators got seriously backed up. Needed more vans to accomodate crowd.

Reviewed on Oct 15, 2025

Hotel Fort Des Moines, Curio Collection by Hilton
4.5-star property

Hotel Fort Des Moines, Curio Collection by Hilton

9.6/10 Exceptional! (1,037 reviews)

Feb 19 - Feb 23

4 night stay

Jacksonville (JAX) to Des Moines (DSM)

Southwest Airlines • Non-stop roundtrip • Coach
Price was $945, price is now $725 per person
$725
per person
found 1 day ago
Beautiful, comfortable room with nice, modern bathroom. Very friendly staff and exceptionally friendly wait staff and bartenders in the Proudfoot & Bird restaurant.

Reviewed on Nov 28, 2025

Hyatt Place West Des Moines Jordan Creek
3.0-star property

Hyatt Place West Des Moines Jordan Creek

9.2/10 Wonderful! (1,004 reviews)

Feb 19 - Feb 23

4 night stay

Jacksonville (JAX) to Des Moines (DSM)

Southwest Airlines • Non-stop roundtrip • Coach
Price was $811, price is now $679 per person
$679
per person
found 1 day ago
This property was incredibly comfortable and convenient for visiting family in the area. I would absolutely stay here again. The pool was even awesome for adults.

Reviewed on Jul 7, 2025

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More About Flying To Knoxville from Daytona Beach

Route Information for Flights from Daytona Beach to Knoxville

Origin Airport IATA Code
DAB
Destination Airport IATA Code
DSM
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

Daytona Beach to Knoxville

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Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.