
$101 Cheap flight deals from Santo Domingo (SDQ) to Medellin (MDE)
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This Weekend's Flight Deals from Santo Domingo to Medellin
This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Airfares from $101 One Way, $212 Round Trip from Santo Domingo to Medellin
Prices starting at $212 for return flights and $101 for one-way flights to Medellin were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Medellin economy flight packages

Aparta Suites Torre Poblado
May 26 - May 30
Santo Domingo (SDQ) to Medellín (MDE)
Reviewed on Jun 12, 2023


The Charlee Hotel
May 28 - Jun 1
Santo Domingo (SDQ) to Medellín (MDE)
Reviewed on Nov 3, 2025
More About Flying To Medellin from Santo Domingo
Route Information for Flights from Santo Domingo to Medellin
Origin Airport IATA Code | SDQ |
|---|---|
Destination Airport IATA Code | MDE |
Distance | |
Direct Flight Airlines | |
Earliest Flight Arrival | |
Latest Flight Arrival |
Santo Domingo to Medellin
Orbitz guarantees you low prices on flights from Santo Domingo to Medellin. In addition to low fares on Santo Domingo to Medellin flights, Orbitz offers fantastic savings on hotels, cruises, vacation packages, and more.
Earn Miles While Saving
Besides helping you fly for the lowest fares, Orbitz lets you earn miles for your frequent flyer program for certain flights from Santo Domingo to Medellin. If you are a member of the frequent flyer or loyalty program offered by the airline you booked through Orbitz or a partner airline’s, simply add your frequent flyer number to your Orbitz reservation to get credit for your Santo Domingo to Medellin flights.
Travel Planning Made Easy
We help take some of the anxiety out of your Santo Domingo to Medellin flights with free flight alerts. We will let you know of flight changes and delays to your flights from Santo Domingo to Medellin by email, voicemail, or text messages to your mobile phone. Alerts can also be sent to up to six other contacts to keep family and business teams informed.
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Frequently asked questions
- Flights to Medellin
- Flights from Santo Domingo
- Santo Domingo Airports
- Medellin Airports
- Airlines Operating
Flights to Medellin
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Flights from Santo Domingo
- Santo Domingo to New York
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Santo Domingo Airports
Medellin Airports
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- Spa Resorts & in Laureles
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- Spa Resorts & in Antioquia
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- Flights from José María Córdova Intl.
- Flights from Bogotá (BOG) to Medellín (MDE)
- Flights from New York (JFK) to Medellín (MDE)
- Flights from Los Angeles (LAX) to Medellín (MDE)
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- Car rental Rionegro
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- Fox Rental Cars Rental Cars in José María Córdova Intl.
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Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.
