$31 Cheap flight deals from Denver (DEN) to Buffalo (MSP)

Earn rewards on top of your airline miles with Orbitz Rewards

Many airlines offer flexible change policies

Sign up to receive text alerts about your trip

This Weekend's Flight Deals from Denver to Buffalo

This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sat, Sep 12 - Tue, Sep 15
DEN
Denver Intl.
MSP
Minneapolis - St. Paul Intl.
$246 Roundtrip, found 10 hours ago
$246
Roundtrip
found 10 hours ago
Select Frontier Airlines flight, departing Sat, Sep 12 from Denver Intl. to Minneapolis - St. Paul Intl., returning Tue, Sep 15, priced at $246 found 10 hours ago
Fri, Sep 11 - Sat, Sep 12
COS
Colorado Springs
MSP
Minneapolis - St. Paul Intl.
$525 Roundtrip, found 2 days ago
$525
Roundtrip
found 2 days ago
Select Southwest Airlines flight, departing Fri, Sep 11 from Colorado Springs to Minneapolis - St. Paul Intl., returning Sat, Sep 12, priced at $525 found 2 days ago

Airfares from $31 One Way, $61 Round Trip from Denver to Buffalo

Prices starting at $61 for return flights and $31 for one-way flights to Buffalo were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Tue, Oct 13 - Sat, Oct 17
DEN
Denver
MSP
Minneapolis
$61 Roundtrip, found 16 hours ago
$61
Roundtrip
found 16 hours ago
Select Frontier Airlines flight, departing Tue, Oct 13 from Denver to Minneapolis, returning Sat, Oct 17, priced at $61 found 16 hours ago
Sat, Oct 31 - Tue, Nov 3
DEN
Denver
MSP
Minneapolis
$66 Roundtrip, found 22 hours ago
$66
Roundtrip
found 22 hours ago
Select Frontier Airlines flight, departing Sat, Oct 31 from Denver to Minneapolis, returning Tue, Nov 3, priced at $66 found 22 hours ago
Wed, Oct 28 - Sat, Oct 31
DEN
Denver
MSP
Minneapolis
$67 Roundtrip, found 1 day ago
$67
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Wed, Oct 28 from Denver to Minneapolis, returning Sat, Oct 31, priced at $67 found 1 day ago
Thu, Nov 5 - Mon, Nov 9
DEN
Denver
MSP
Minneapolis
$147 Roundtrip, just found
$147
Roundtrip
just found
Select Sun Country Airlines flight, departing Thu, Nov 5 from Denver to Minneapolis, returning Mon, Nov 9, priced at $147 just found
Sat, Oct 17 - Tue, Oct 27
DEN
Denver
MSP
Minneapolis
$159 Roundtrip, just found
$159
Roundtrip
just found
Select Southwest Airlines flight, departing Sat, Oct 17 from Denver to Minneapolis, returning Tue, Oct 27, priced at $159 just found

Buffalo economy flight packages

Price found within the past 48 hours. Click for updated prices.
Lakeville Inn
2.5-star property

Lakeville Inn

8.8/10 Excellent! (175 reviews)

Oct 16 - Oct 19

3 night stay

Denver (DEN) to Minneapolis (MSP)

Frontier Airlines • Roundtrip • Coach
Price was $352, price is now $286 per person
$286
per person
found 1 day ago
It was a good hotel, I'd definitely stay here again. My daughter also thought it was a nice hotel!

Reviewed on Sep 7, 2026

Candlewood Suites Eagan Arpt South - Mall Area by IHG
3.5-star property

Candlewood Suites Eagan Arpt South - Mall Area by IHG

8.8/10 Excellent! (654 reviews)

Oct 15 - Oct 18

3 night stay

Denver (DEN) to Minneapolis (MSP)

Frontier Airlines • Roundtrip • Coach
Price was $386, price is now $319 per person
$319
per person
found 7 hours ago
Extremely helpful desk staff, sometimes you just can't figure out the super-safe stove. Every time I needed something the answers were prompt and accurate. Pool area was well maintained and very nice. Overall this be a repeat stay when we come this way again.

Reviewed on Sep 6, 2026

Emery, Autograph Collection Hotel
4.5-star property

Emery, Autograph Collection Hotel

9.2/10 Wonderful! (827 reviews)

Oct 8 - Oct 11

3 night stay

Denver (DEN) to Minneapolis (MSP)

Delta • Coach

Minneapolis (MSP) to Denver (DEN)

Frontier Airlines • Coach
Price was $759, price is now $574 per person
$574
per person
found 1 day ago

Don't see what you're looking for?
See all available trips from Denver to Buffalo
View all trips

More About Flying To Buffalo from Denver

Route Information for Flights from Denver to Buffalo

Origin Airport IATA Code
DEN
Destination Airport IATA Code
MSP
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

Denver to Buffalo

Planning a romantic getaway, traveling the world at last or flying out to see the kids and grandkids? Orbitz On-the-Go saves you both time and money. Our cutting edge mobile tools and guaranteed low prices leave plenty of room in your budget for the important things in life. Find same-day deals on domestic flights from Denver to Buffalo, and bargain sales on international Denver to Buffalo flights.

Family Matters, and So Do Cheap Tickets

Don’t miss another birthday, graduation or wedding, wherever they are. Take advantage of Orbitz On-the-Go’s discount travel planning features to save on flights from Denver to Buffalo and Denver to Buffalo flights. Tell them you’ll be there, every single time.

Escape to Romance

Treat yourself and the one you love to a romantic hideaway. Orbitz budget air flights from Denver to Buffalo and Denver to Buffalo flights can be bundled into packages for extravagant savings at spa resorts and hotels.

See the World

It’s finally your time. Go wherever the wind takes you. Orbitz On-the-Go makes dreams come true. Book low fare flights from Denver to Buffalo, the world is at your fingertips.

Flight or Gate Changes? No Problem

Once you’ve reserved your low cost air ticket on Denver to Buffalo flights or flights from Denver to Buffalo, stay informed with Orbitz On-the-Go free alerts. Choose from email, voice and text notification. You’ll always know your flight status and gate number, and where and how to pick up your bags.

More Destinations

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.