$174 Cheap flight deals from Guayaquil (GYE) to Panama City (PTY)

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This Weekend's Flight Deals from Guayaquil to Panama City

This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sat, Jan 17 - Mon, Jan 19
GYE
Jose Joaquin de Olmedo Intl.
PTY
Tocumen Intl.
$358 Roundtrip, just found
$358
Roundtrip
just found
Select avianca flight, departing Sat, Jan 17 from Jose Joaquin de Olmedo Intl. to Tocumen Intl., returning Mon, Jan 19, priced at $358 just found

Airfares from $174 One Way, $335 Round Trip from Guayaquil to Panama City

Prices starting at $335 for return flights and $174 for one-way flights to Panama City were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Tue, Feb 3 - Fri, Feb 6
GYE
Guayaquil
PTY
Panama City
$335 Roundtrip, found 3 days ago
$335
Roundtrip
found 3 days ago
Select Copa flight, departing Tue, Feb 3 from Guayaquil to Panama City, returning Fri, Feb 6, priced at $335 found 3 days ago
Tue, Feb 3 - Fri, Feb 6
GYE
Guayaquil
PTY
Panama City
$347 Roundtrip, found 3 days ago
$347
Roundtrip
found 3 days ago
Select Copa flight, departing Tue, Feb 3 from Guayaquil to Panama City, returning Fri, Feb 6, priced at $347 found 3 days ago
Tue, Feb 3 - Fri, Feb 6
GYE
Guayaquil
PTY
Panama City
$354 Roundtrip, found 3 days ago
$354
Roundtrip
found 3 days ago
Select avianca flight, departing Tue, Feb 3 from Guayaquil to Panama City, returning Fri, Feb 6, priced at $354 found 3 days ago
Fri, Feb 6 - Mon, Feb 9
GYE
Guayaquil
PTY
Panama City
$355 Roundtrip, found 2 hours ago
$355
Roundtrip
found 2 hours ago
Select avianca flight, departing Fri, Feb 6 from Guayaquil to Panama City, returning Mon, Feb 9, priced at $355 found 2 hours ago
Sun, Jan 25 - Sat, Jan 31
GYE
Guayaquil
PTY
Panama City
$356 Roundtrip, found 15 hours ago
$356
Roundtrip
found 15 hours ago
Select avianca flight, departing Sun, Jan 25 from Guayaquil to Panama City, returning Sat, Jan 31, priced at $356 found 15 hours ago

Panama City economy flight packages

Price found within the past 48 hours. Click for updated prices.
Hotel Riu Plaza Panama
5.0-star property

Hotel Riu Plaza Panama

9/10 Wonderful! (4,515 reviews)

Feb 22 - Mar 1

7 night stay

Guayaquil (GYE) to Panama City (PTY)

Copa • Roundtrip • Coach
Save 100% on your flight
Price was $1,158, price is now $771 per person
$771
per person
found 1 hour ago
Those three options was good

Reviewed on Jan 3, 2026

Dreams Playa Bonita Panama - All Inclusive
4.0-star property

Dreams Playa Bonita Panama - All Inclusive

7.4/10 Good! (1,002 reviews)

Feb 14 - Feb 17

3 night stay

Guayaquil (GYE) to Panama City (PTY)

Copa • Roundtrip • Coach
Save 100% on your flight
Price was $1,933, price is now $1,369 per person
$1,369
per person
found 1 day ago
Several restaurants onsite. Beach was beautiful! Lots of entertainment!

Reviewed on Nov 10, 2025

Central Hotel Panama Casco Viejo
4.0-star property

Central Hotel Panama Casco Viejo

9/10 Wonderful! (1,002 reviews)

Feb 14 - Feb 17

3 night stay

Guayaquil (GYE) to Panama City (PTY)

Copa • Roundtrip • Coach
Save 100% on your flight
Price was $2,580, price is now $1,890 per person
$1,890
per person
found 1 day ago
Kimberly at the Front Desk was wonderful!

Reviewed on Jun 8, 2025

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More About Flying To Panama City from Guayaquil

Route Information for Flights from Guayaquil to Panama City

Origin Airport IATA Code
GYE
Destination Airport IATA Code
PTY
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

Guayaquil to Panama City

Great Deals on Flights From Guayaquil to Panama City

Spend more of your time and money at Panama City instead of sitting at your computer, searching for discount Guayaquil to Panama City flights. This is why Orbitz makes it easy for you to check out destinations, plan your trip, and book your air fare, hotel, car rental, and more in just one place. Our low price guarantee means that you get great deals on flights from Guayaquil to Panama City.

Flights That Fit Your Budget

Traveling on a budget? Not to worry if you are using Orbitz. We monitor thousands of fares to make sure we show you the best air ticket prices available for your travel dates. Besides amazing prices on Guayaquil to Panama City flights, we offer you great deals on hotels, vacation packages, and last-minute getaways for the perfect trip.

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Search for Flights from Guayaquil to Panama City on the Go

Orbitz offers free mobile apps for iPad, iPhone, and Android-based devices, so even the busiest trip-planner can research and book flights from Guayaquil to Panama City. Find cheap Guayaquil to Panama City flights, research local festivities and attractions, and book reservations while sitting in the salon. Orbitz will also update you on flight delays with free alerts sent to your mobile phone or email address, so you’re never left in the dark.

Frequently asked questions

Are there non-stop flights from Guayaquil to Panama City?
Work out your ideal travel dates, because there is. You can fly from Airport of Guayaquil to Panama City (PTY-Tocumen Intl.) in one simple journey with Copa Airlines.
What is the shortest flight from Guayaquil to Panama City?
Leave that movie marathon for some other time, because the journey from Guayaquil to Panama City can take as little as 2 hours and 6 minutes.
What airlines fly from Guayaquil to Panama City most frequently?
Copa Airlines has the most flights along this route. This popular airline operates 152 flights from Guayaquil to Panama City each month.
What is the cheapest day of the week to fly?
Consider flying out early in the week to save on your airfare. Orbitz data from 2021 shows that Monday is the cheapest day to depart, followed by Tuesday. Saturday showed the highest average ticket prices likely because many travelers prefer to start their vacation on a weekend.
What is the cheapest month to fly?
We won't keep you guessing, according to Orbitz data from 2021, the cheapest month to fly is February. Perfect for those who need a weekend getaway, or just a break from it all in the shortest month of the year. Be aware that the most expensive time to fly is during the height of summer in July, and in the holiday month of December.*According to flight demand on Orbitz.com from January to December 2021. Savings are subject to change based on departure location, date and destination.

More Destinations

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.