Pet Friendly Hotels in South Carolina Midlands, SC
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Tomorrow night
Check prices in South Carolina Midlands for tomorrow night, Oct 31 - Nov 1Featured South Carolina Midlands Pet Friendly Hotels

La Quinta Inn & Suites by Wyndham Florence
2123 W Lucas St, Florence, SC
Free Cancellation
Reserve now, pay when you stay
$99 nightly
The price is $111 total per night
$111 total
Nov 17 - Nov 18
Total with taxes and fees
Guests of La Quinta Inn & Suites by Wyndham Florence enjoy a gym, free WiFi in public areas, and meeting rooms. If you plan to drive, free parking is available. The 24-hour front desk has multilingual staff ready to help secure valuables, and answer any questions about the area. Additional amenities include a 24-hour business center, a seasonal outdoor pool, and coffee/tea in a common area.
Pool
Breakfast included

La Quinta Inn by Wyndham Columbia SE / Fort Jackson
7333 Garners Ferry Rd, Columbia, SC
Free Cancellation
Reserve now, pay when you stay
$84 nightly
The price is $94 total per night
$94 total
Nov 2 - Nov 3
Total with taxes and fees
Guests of La Quinta Inn by Wyndham Columbia SE / Fort Jackson enjoy access to free WiFi in public areas, a 24-hour business center, and a seasonal outdoor pool. If you plan to drive, free parking is available. The 24-hour front desk has staff always at the ready. Additional amenities include coffee/tea in a common area and a TV in a common area.
Pool
Breakfast included

Hampton Inn Columbia I-26/Harbison Blvd.
101 Woodcross Dr, Columbia, SC
Free Cancellation
Reserve now, pay when you stay
$98 nightly
The price is $109 total per night
$109 total
Nov 9 - Nov 10
Total with taxes and fees
At Hampton Inn Columbia I-26/Harbison Blvd., guests enjoy an outdoor pool, a gym, and free WiFi in public areas. If you decide to drive, there's free parking. Multilingual staff at the front desk are standing by 24/7 to help with securing valuables, luggage storage, and tours or tickets. Additional amenities include conference space, a 24-hour business center, and coffee/tea in a common area.
Pool
Breakfast included

Spark by Hilton Orangeburg
731 Citadel Road, Orangeburg, SC
Free Cancellation
Reserve now, pay when you stay
$87 nightly
The price is $97 total per night
$97 total
Nov 9 - Nov 10
Total with taxes and fees
Renovated in 2025, Spark by Hilton Orangeburg offers a gym, free WiFi in public areas, and a seasonal outdoor pool. If you drive, take advantage of free parking. Front-desk staff are standing by 24/7 to assist with any requests. If you like to take your furry friend along on your adventures, this pet-friendly property offers food and water bowls. Additional amenities include coffee/tea in a common area, a meeting room, and express check-out.
Pool
Breakfast included

Quality Inn & Suites Florence Civic Center
150 Dunbarton Dr, Florence, SC
Free Cancellation
Reserve now, pay when you stay
$76 nightly
The price is $86 total per night
$86 total
Nov 30 - Dec 1
Total with taxes and fees
Guests of Quality Inn & Suites Florence Civic Center enjoy a gym, free WiFi in public areas, and a business center. Free parking is included with your stay. The 24-hour front desk has staff standing by to help with luggage storage, securing valuables, and dry cleaning/laundry. Additional amenities include a seasonal outdoor pool, coffee/tea in a common area, and a meeting room.
Pool
Breakfast included

Holiday Inn Santee by IHG
139 Bradford Blvd, Santee, SC
Free Cancellation
$123 nightly
The price is $137 total per night
$137 total
Nov 2 - Nov 3
Total with taxes and fees
At Holiday Inn Santee by IHG, guests enjoy an indoor pool, a 24-hour gym, and free WiFi in public areas. Free parking is available if you drive. The 24-hour front desk has staff standing by to help with securing valuables and luggage storage. Other amenities at this golf hotel include meeting rooms, conference space, and a business center.
Pool
Pet friendly

Red Roof Inn Florence - Civic Center
2690 David H McLeod Boulevard, Florence, SC
Free Cancellation
Reserve now, pay when you stay
$56 nightly
The price is $63 total per night
$63 total
Nov 3 - Nov 4
Total with taxes and fees
Guests of Red Roof Inn Florence - Civic Center enjoy free WiFi in public areas, coffee in a common area, and a vending machine. Free parking is included with your stay. The 24-hour front desk has staff always at the ready. This smoke-free hotel also has an ATM.
Pet friendly
Parking included

Baymont Inn & Suites Florence by Wyndham
1826 W Lucas Street, Florence, SC
Guests of Baymont Inn & Suites Florence by Wyndham enjoy a gym, free WiFi in public areas, and meeting rooms. If you drive, take advantage of free parking. The 24-hour front desk has staff standing by to help with dry cleaning or laundry, and answer any questions about the accommodations. Additional amenities include a business center, a seasonal outdoor pool, and coffee/tea in a common area.
Pool
Pet friendly

Best Western Inn
1808 W Lucas Street, Florence, SC
Free Cancellation
Reserve now, pay when you stay
$79 nightly
The price is $88 total per night
$88 total
Nov 2 - Nov 3
Total with taxes and fees
Guests of Best Western Inn enjoy access to free WiFi in public areas, a business center, and a seasonal outdoor pool. Free parking is included with your stay. Front-desk staff are standing by 24/7 to assist with any requests. Additional amenities include express check-out and a vending machine.
Pool
Breakfast included

Baymont by Wyndham Manning
2284 Raccoon Road, Manning, SC
Free Cancellation
Reserve now, pay when you stay
$85 nightly
The price is $94 total per night
$94 total
Nov 2 - Nov 3
Total with taxes and fees
Guests of Baymont by Wyndham Manning enjoy free WiFi in public areas, a business center, and laundry facilities. If you plan to drive, free parking is available. Front-desk staff are standing by 24/7 to assist with any requests. This hotel also has a vending machine.
Breakfast included
Parking included

Clarion Pointe Near University
1106 N. Anderson Road, Rock Hill, SC
Free Cancellation
Reserve now, pay when you stay
$71 nightly
The price is $79 total per night
$79 total
Nov 2 - Nov 3
Total with taxes and fees
At Clarion Pointe Rock Hill Near University, guests have access to a gym, free WiFi in public areas, and a 24-hour business center. Free parking is included with your stay. The 24-hour front desk has staff standing by to help with luggage storage, and answer any questions about the accommodations. This hotel also has laundry facilities.
Breakfast included
Pet friendly

TownePlace Suites by Marriott Florence
2650 Hospitality Boulevard, Florence, SC
Free Cancellation
Reserve now, pay when you stay
$95 nightly
The price is $107 total per night
$107 total
Nov 2 - Nov 3
Total with taxes and fees
Guests staying at TownePlace Suites by Marriott Florence enjoy an outdoor pool, a 24-hour gym, and free WiFi in public areas. If you decide to drive, there's free parking. The 24-hour front desk has staff standing by to help with dry cleaning/laundry and securing valuables. Additional amenities include conference space, a 24-hour business center, and coffee/tea in a common area.
Pool
Breakfast included

Days Inn by Wyndham Florence/I-95 North
2111 West Lucas St/I-95, I-95 & Hwy 52 Exit 164, Florence, SC
Free Cancellation
Reserve now, pay when you stay
$58 nightly
The price is $65 total per night
$65 total
Nov 28 - Nov 29
Total with taxes and fees
At Days Inn by Wyndham Florence/I-95 North, guests have access to free WiFi in public areas, a seasonal outdoor pool, and free newspapers. If you plan to drive, free parking is available. The 24-hour front desk has staff standing by to help secure valuables, and answer any questions about the accommodations. Additional amenities include laundry facilities, a vending machine, and a garden.
Pool
Breakfast included

La Quinta Inn by Wyndham Columbia NE/Fort Jackson
1538 Horseshoe Drive, Columbia, SC
Free Cancellation
Reserve now, pay when you stay
$87 nightly
The price is $98 total per night
$98 total
Nov 9 - Nov 10
Total with taxes and fees
Guests staying at La Quinta Inn by Wyndham Columbia NE/Fort Jackson enjoy an outdoor pool, a gym, and free WiFi in public areas. Free parking is included with your stay. Front-desk staff are standing by 24/7 to assist with any requests. Additional amenities include a business center, a seasonal outdoor pool, and coffee/tea in a common area.
Pool
Breakfast included

Residence Inn Marriott Florence
2660 Hospitality Blvd, Florence, SC
Free Cancellation
Reserve now, pay when you stay
$99 nightly
The price is $111 total per night
$111 total
Nov 16 - Nov 17
Total with taxes and fees
At Residence Inn Marriott Florence, guests enjoy an outdoor pool, a gym, and free WiFi in public areas. If you drive, put free parking to good use. The 24-hour front desk has staff standing by to help with dry cleaning or laundry, and answer any questions about the accommodations. Additional amenities include meeting rooms, a business center, and a seasonal outdoor pool.
Pool
Breakfast included
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See all available properties in South Carolina Midlands
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
South Carolina Midlands hotels essential information
Accommodation | 2,966 hotels |
|---|---|
Lowest Price | $63 |
Highest Price | $137 |
Popular hotels | La Quinta Inn & Suites by Wyndham Florence, La Quinta Inn by Wyndham Columbia SE / Fort Jackson, Hampton Inn Columbia I-26/Harbison Blvd., Spark by Hilton Orangeburg, Quality Inn & Suites Florence Civic Center, Holiday Inn Santee by IHG, Red Roof Inn Florence - Civic Center, Baymont Inn & Suites Florence by Wyndham, Best Western Inn, Baymont by Wyndham Manning, Clarion Pointe Near University, TownePlace Suites by Marriott Florence, Days Inn by Wyndham Florence/I-95 North, La Quinta Inn by Wyndham Columbia NE/Fort Jackson, Residence Inn Marriott Florence |
Recent Pet Friendly Hotels Reviews

Clarion Pointe Near University
5/5 Excellent
"Rooms were very clean and beds were extremely comfortable. Appreciated the blackout shades on the windows. Only complaint was the WiFi didn’t work but it wasn’t a huge deal. "
A verified traveler stayed at Clarion Pointe Near University
Posted 3 days ago
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