Pet Friendly Hotels in South Carolina Midlands, SC
Earn Orbucks instantly: $1 Orbuck = $1 USD, good toward hotels
Save 10% or more on select hotels with Insider Prices
Book on the app to instantly earn 5% on 350,000+ hotels
Tomorrow night
Check prices in South Carolina Midlands for tomorrow night, Jul 28 - Jul 29Featured South Carolina Midlands Pet Friendly Hotels

La Quinta Inn & Suites by Wyndham Florence
2123 W Lucas St, Florence, SC
Free Cancellation
Reserve now, pay when you stay
$96 nightly
The price is $108 total per night
$108 total
Aug 17 - Aug 18
Total includes taxes and fees
Guests of La Quinta Inn & Suites by Wyndham Florence enjoy a gym, free WiFi in public areas, and meeting rooms. If you plan to drive, free parking is available. The 24-hour front desk has staff standing by to help secure valuables, and answer any questions about the accommodations. Additional amenities include a 24-hour business center, a seasonal outdoor pool, and coffee/tea in a common area.

La Quinta Inn by Wyndham Columbia SE / Fort Jackson
7333 Garners Ferry Rd, Columbia, SC
Free Cancellation
Reserve now, pay when you stay
$86 nightly
The price is $96 total per night
$96 total
Aug 17 - Aug 18
Total includes taxes and fees
Guests of La Quinta Inn by Wyndham Columbia SE / Fort Jackson enjoy access to free WiFi in public areas, a 24-hour business center, and a seasonal outdoor pool. If you plan to drive, free parking is available. The 24-hour front desk has staff always at the ready. Additional amenities include coffee/tea in a common area and a TV in a common area.

Hampton Inn Columbia I-26/Harbison Blvd.
101 Woodcross Dr, Columbia, SC
Free Cancellation
Reserve now, pay when you stay
$101 nightly
The price is $113 total per night
$113 total
Aug 10 - Aug 11
Total includes taxes and fees
At Hampton Inn Columbia I-26/Harbison Blvd., guests enjoy an outdoor pool, a gym, and free WiFi in public areas. If you decide to drive, there's free parking. Multilingual staff at the front desk are standing by 24/7 to help with securing valuables, luggage storage, and dry cleaning/laundry. Additional amenities include conference space, a 24-hour business center, and coffee/tea in a common area.

Spark by Hilton Orangeburg
731 Citadel Road, Orangeburg, SC
Free Cancellation
Reserve now, pay when you stay
$93 nightly
The price is $103 total per night
$103 total
Aug 3 - Aug 4
Total includes taxes and fees
Renovated in 2025, Spark by Hilton Orangeburg offers a gym, free WiFi in public areas, and a seasonal outdoor pool. If you drive, take advantage of free parking. Front-desk staff are standing by 24/7 to assist with any requests. If you like to take your furry friend along on your adventures, this pet-friendly property offers food and water bowls. Additional amenities include coffee/tea in a common area, a meeting room, and express check-out.

Quality Inn & Suites Florence Civic Center
150 Dunbarton Dr, Florence, SC
Free Cancellation
Reserve now, pay when you stay
$85 nightly
The price is $95 total per night
$95 total
Aug 25 - Aug 26
Total includes taxes and fees
Guests of Quality Inn & Suites Florence Civic Center enjoy a gym, free WiFi in public areas, and a business center. Free parking is included with your stay. The 24-hour front desk has staff standing by to help with luggage storage, securing valuables, and dry cleaning/laundry. Additional amenities include a seasonal outdoor pool, coffee/tea in a common area, and a meeting room.

Holiday Inn Santee by IHG
139 Bradford Blvd, Santee, SC
Free Cancellation
$129 nightly
The price is $143 total per night
$143 total
Jul 28 - Jul 29
Total includes taxes and fees
At Holiday Inn Santee by IHG, guests enjoy an indoor pool, a 24-hour gym, and free WiFi in public areas. Free parking is available if you drive. The 24-hour front desk has staff standing by to help with luggage storage and securing valuables. Other amenities at this golf hotel include meeting rooms, conference space, and a business center.

Red Roof Inn Florence - Civic Center
2690 David H McLeod Boulevard, Florence, SC
Free Cancellation
Reserve now, pay when you stay
$56 nightly
The price is $63 total per night
$63 total
Jul 30 - Jul 31
Total includes taxes and fees
Guests of Red Roof Inn Florence - Civic Center enjoy free WiFi in public areas, coffee in a common area, and a vending machine. Free parking is included with your stay. The 24-hour front desk has staff always at the ready. This smoke-free hotel also has an ATM.

Baymont Inn & Suites Florence by Wyndham
1826 W Lucas Street, Florence, SC
Guests of Baymont Inn & Suites Florence by Wyndham enjoy a gym, free WiFi in public areas, and meeting rooms. If you drive, take advantage of free parking. The 24-hour front desk has staff standing by to help with dry cleaning or laundry, and answer any questions about the accommodations. Additional amenities include a business center, a seasonal outdoor pool, and coffee/tea in a common area.

Best Western Inn
1808 W Lucas Street, Florence, SC
Free Cancellation
Reserve now, pay when you stay
$99 nightly
The price is $111 total per night
$111 total
Jul 28 - Jul 29
Total includes taxes and fees
Guests of Best Western Inn enjoy access to free WiFi in public areas, a business center, and a seasonal outdoor pool. Free parking is included with your stay. Front-desk staff are standing by 24/7 to assist with any requests. Additional amenities include express check-out and a vending machine.

Baymont by Wyndham Manning
2284 Raccoon Road, Manning, SC
Free Cancellation
Reserve now, pay when you stay
$89 nightly
The price is $99 total per night
$99 total
Aug 21 - Aug 22
Total includes taxes and fees
Guests of Baymont by Wyndham Manning enjoy free WiFi in public areas, a business center, and laundry facilities. If you plan to drive, free parking is available. Front-desk staff are standing by 24/7 to assist with any requests. This hotel also has a vending machine.

Clarion Pointe Near University
1106 N. Anderson Road, Rock Hill, SC
Free Cancellation
Reserve now, pay when you stay
$75 nightly
The price is $84 total per night
$84 total
Aug 10 - Aug 11
Total includes taxes and fees
At Clarion Pointe Near University, guests have access to a gym, free WiFi in public areas, and a 24-hour business center. Free parking is included with your stay. The 24-hour front desk has staff standing by to help with luggage storage, and answer any questions about the accommodations. This hotel also has laundry facilities.

TownePlace Suites by Marriott Florence
2650 Hospitality Boulevard, Florence, SC
Free Cancellation
Reserve now, pay when you stay
$111 nightly
The price is $125 total per night
$125 total
Jul 29 - Jul 30
Total includes taxes and fees
Guests staying at TownePlace Suites by Marriott Florence enjoy an outdoor pool, a 24-hour gym, and free WiFi in public areas. If you decide to drive, there's free parking. The 24-hour front desk has staff standing by to help with dry cleaning/laundry and securing valuables. Additional amenities include conference space, a 24-hour business center, and coffee/tea in a common area.

Days Inn by Wyndham Florence/I-95 North
2111 West Lucas St/I-95, I-95 & Hwy 52 Exit 164, Florence, SC
Free Cancellation
Reserve now, pay when you stay
$61 nightly
The price is $69 total per night
$69 total
Aug 10 - Aug 11
Total includes taxes and fees
At Days Inn by Wyndham Florence/I-95 North, guests have access to free WiFi in public areas, a seasonal outdoor pool, and free newspapers. If you plan to drive, free parking is available. The 24-hour front desk has staff standing by to help secure valuables, and answer any questions about the accommodations. Additional amenities include laundry facilities, a vending machine, and a TV in a common area.

La Quinta Inn by Wyndham Columbia NE/Fort Jackson
1538 Horseshoe Drive, Columbia, SC
$82 nightly
The price is $92 total per night
$92 total
Aug 3 - Aug 4
Total includes taxes and fees
Guests staying at La Quinta Inn by Wyndham Columbia NE/Fort Jackson enjoy an outdoor pool, a gym, and free WiFi in public areas. Free parking is included with your stay. Front-desk staff are standing by 24/7 to assist with any requests. Additional amenities include a business center, a seasonal outdoor pool, and coffee/tea in a common area.

Residence Inn Marriott Florence
2660 Hospitality Blvd, Florence, SC
Free Cancellation
Reserve now, pay when you stay
$118 nightly
The price is $132 total per night
$132 total
Aug 3 - Aug 4
Total includes taxes and fees
At Residence Inn Marriott Florence, guests enjoy an outdoor pool, a gym, and free WiFi in public areas. If you drive, put free parking to good use. The 24-hour front desk has staff standing by to help with dry cleaning or laundry, and answer any questions about the accommodations. Additional amenities include meeting rooms, a business center, and a seasonal outdoor pool.
Don't see what you're looking for?
See all available properties in South Carolina Midlands
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
South Carolina Midlands hotels essential information
Accommodation | 2,949 hotels |
---|---|
Lowest Price | $63 |
Highest Price | $143 |
Popular hotels | La Quinta Inn & Suites by Wyndham Florence, La Quinta Inn by Wyndham Columbia SE / Fort Jackson, Hampton Inn Columbia I-26/Harbison Blvd., Spark by Hilton Orangeburg, Quality Inn & Suites Florence Civic Center, Holiday Inn Santee by IHG, Red Roof Inn Florence - Civic Center, Baymont Inn & Suites Florence by Wyndham, Best Western Inn, Baymont by Wyndham Manning, Clarion Pointe Near University, TownePlace Suites by Marriott Florence, Days Inn by Wyndham Florence/I-95 North, La Quinta Inn by Wyndham Columbia NE/Fort Jackson, Residence Inn Marriott Florence |
Recent Pet Friendly Hotels Reviews

Clarion Pointe Near University
5/5 Excellent
"We were in town for a U14 Perfect Game Baseball tournament. The Clarian met and exceeded all expectations from check in to breakfast, getting extra towels and toothpaste to getting an extended checkout. It was great location to the game, sporting goods stores along with food and entertainment. I would definitely recommend and stay there again for future events."
A verified traveler stayed at Clarion Pointe Near University
Posted 1 day ago
Other Pet Friendly Hotels
Areas Of South Carolina Midlands
Hotels Near
Hotel Themes
Flights To
Other Popular Accommodations
Top Trending
Hotels
- All Inclusive Resorts & Hotels in Coastal South Carolina
- Oceanfront Hotels in Coastal South Carolina
- Hotels in Carolina Forest
- Waterpark Hotels & Resorts in Coastal South Carolina
- Hotels with Free Airport Shuttle in Greenville - Spartanburg
- Hotels in Greenville Downtown
- Hotels in Charleston Historic District
- Hotels near Myrtle Beach Convention Center
- Gay Friendly Hotels in Coastal South Carolina
- Spa Resorts & Hotels in Upstate South Carolina
- Hotels near Broadway at the Beach
- Kid Friendly Hotels in Upstate South Carolina
- Hotels in Cherry Grove Beach
- Hotels near Coastal Carolina University
- Hotels in Downtown Myrtle Beach
- Hotels with Free Parking in Charleston Historic District
- Hotels with Kitchenettes in Coastal South Carolina
- Hotels with Hot Tubs in Upstate South Carolina
- Hotels in West Ashley
- Hotels in Downtown Charleston
- Hotels near Rock Hill Sports & Event Center
- Hotels near Charleston Tanger Outlets
- Hotels near Pier at Garden City
- Pet Friendly Hotels in Cherry Grove Beach