See all properties

Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG

2.5 star property
Hotel with free breakfast, steps from Market Arcade Building

Choose dates to view prices

Photo gallery for Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG

1 bedroom, in-room safe, desk, laptop workspace
Free daily buffet breakfast
Lobby sitting area
Business center
Lobby sitting area

Reviews

8.6 out of 10
Excellent

Popular amenities

  • Free WiFi
  • Air conditioning
  • Gym
  • Business services
  • Laundry

Explore the area

View in a map
601 Main St, Buffalo, NY, 14203
  • Place, Chippewa District
    ‪1 min walk‬
  • Place, Shea's Performing Arts Center
    ‪2 min walk‬
  • Place, Buffalo Niagara Convention Center
    ‪5 min walk‬
  • Airport, Buffalo, NY (BUF-Buffalo Niagara Intl.)
    ‪13 min drive‬

Room options

View all photos for Standard Room

Standard Room | 1 bedroom, in-room safe, desk, laptop workspace

Standard Room

9.2 out of 10
Wonderful
(25 reviews)
  • 500 sq ft
  • Sleeps 2
  • 1 King Bed and 1 Double Sofa Bed

View all photos for Suite, 1 Bedroom

Suite, 1 Bedroom | 1 bedroom, in-room safe, desk, laptop workspace

Suite, 1 Bedroom

9.0 out of 10
Wonderful
(44 reviews)
  • 500 sq ft
  • 1 bedroom
  • City view
  • Sleeps 4
  • 1 King Bed

View all photos for Suite, 1 Bedroom, Accessible (Mobility Accessible, Bathtub)

Combined shower/tub, eco-friendly toiletries, hair dryer, towels

Suite, 1 Bedroom, Accessible (Mobility Accessible, Bathtub)

9.6 out of 10
Exceptional
(4 reviews)
  • 500 sq ft
  • Sleeps 4
  • 1 Queen Bed

View all photos for Suite, 1 Bedroom, Accessible (Mobility Accessible, Roll-in Shower)

Combined shower/tub, eco-friendly toiletries, hair dryer, towels

Suite, 1 Bedroom, Accessible (Mobility Accessible, Roll-in Shower)

9.0 out of 10
Wonderful
(4 reviews)
  • 500 sq ft
  • Sleeps 4
  • 1 Queen Bed

You may also like

Ad
Indoor pool

Hyatt Regency Buffalo / Hotel and Conference Center

Downtown Buffalo
  • Pool
  • Pet friendly
  • Free WiFi
  • Restaurant
8.2 out of 10, Very Good, 1,684 reviews
$143 nightly
The price is $167
Jan 8 - Jan 9, 2026
Total with taxes and fees
Hyatt Regency Buffalo / Hotel and Conference Center

About the neighborhood

Buffalo

Located in Downtown Buffalo, Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG is next to popular attractions like Market Arcade Building and Buffalo Music Hall of Fame. This 146-room hotel welcomes guests with free breakfast and conveniences like free in-room WiFi and a gym.

What's nearby

  • Chippewa District - 1 min walk - 0.0 miles
  • Shea's Performing Arts Center - 2 min walk - 0.1 miles
  • Fountain Plaza - 2 min walk - 0.1 miles
  • Buffalo Niagara Convention Center - 5 min walk - 0.3 miles
  • Niagara Square - 6 min walk - 0.4 miles

Getting around

  • Fountain Plaza Station - 1 min walk
  • Buffalo-Exchange Street Station - 18 min walk
  • Buffalo Niagara Intl. Airport (BUF) - 21 min drive

Restaurants

  • ‪Bada Bing - ‬2 min walk
  • ‪The House Of Charm - ‬4 min walk
  • ‪Streetlight Brasserie - ‬3 min walk
  • ‪Soho Burger Bar - ‬3 min walk
  • ‪Eddie Brady's - ‬3 min walk

About this property

Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG

Hotel with free breakfast, steps from Market Arcade Building
Guests of Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG enjoy a gym, free WiFi in public areas, and a business center. Front-desk staff can answer questions 24/7, and assist with securing valuables, dry cleaning/laundry, and luggage storage. Additional amenities include express check-out, laundry facilities, and a vending machine.
Guests can expect free WiFi and 49-inch TVs with cable channels. Bathrooms have hair dryers and free toiletries. Other amenities include sofa beds, sitting areas, and refrigerators.
Recreational amenities at the hotel include a fitness center.

Similar properties

Lobby
Wyndham Garden Buffalo Downtown
  • Breakfast included
  • Free WiFi
  • Restaurant
  • Air conditioning
9.0 out of 10, Wonderful, 1,717 reviews
$124 nightly
The price is $144
Jan 5 - Jan 6, 2026
Total with taxes and fees
Wyndham Garden Buffalo Downtown

Property amenities

Internet

  • Available in all rooms: Free WiFi
  • Available in some public areas: Free WiFi

Parking and transportation

  • Offsite parking available (USD 16 per day)
  • Wheelchair-accessible parking and van parking available
  • Onsite parking options include a garage

Food and drink

  • Free buffet breakfast available daily 6:00 AM to 10:00 AM

Things to do

  • Gym

Family friendly

  • In-room crib
  • In-room microwave
  • In-room refrigerator
  • In-room sofa bed
  • Laundry facilities
  • Living room
  • Separate bedroom

Conveniences

  • 24-hour front desk
  • Guidebooks
  • Laundry facilities
  • Luggage storage
  • Safe at front desk
  • Vending machine

Guest services

  • Dry cleaning/laundry service
  • Housekeeping (daily)

Business services

  • Business center

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Assistive listening devices
  • Elevator
  • Grab bar in shower
  • Grab bar near toilet
  • Hand-held showerhead
  • Handrails in stairways
  • Height-adjustable showerhead
  • In-room roll-in shower
  • Lever door handles
  • Low-height electrical outlets in bathroom
  • Portable shower seat
  • Raised toilet seat
  • Visual fire alarm
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible bathroom vanity
  • Wheelchair-accessible business center
  • Wheelchair-accessible gym
  • Wheelchair-accessible parking
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible path to elevator
  • Wheelchair-accessible public washroom
  • Wheelchair-accessible registration desk
  • Wheelchair-accessible restaurant
  • Wheelchair-accessible van parking

More

  • 7 floors
  • At least 80% lighting from LEDs
  • Comprehensive food waste policy
  • Eco-friendly cleaning products used
  • Smoking not allowed
  • Vegetarian breakfast available
  • Vegetarian dining options

Room amenities

Bedroom

  • Bedsheets provided
  • Blackout drapes
  • Double sofa bed
  • Free crib

Bathroom

  • Free toiletries
  • Hair dryer
  • Private bathroom
  • Shower/bathtub combination
  • Towels provided

Entertainment

  • 49-inch TV with cable channels

Food and drink

  • Coffee/tea maker
  • Microwave
  • Refrigerator
  • Restaurant dining guides

More

  • Air conditioning (climate-controlled)
  • Bulk dispensers for toiletries
  • Connecting rooms available
  • Desk
  • Eco-friendly toiletries
  • Free local calls
  • Heating
  • Iron/ironing board
  • Laptop workspace
  • LED lighting
  • Living room
  • Phone
  • Safe
  • Separate sitting area

Policies

Check-in

Check-in start time: 3:00 PM; Check-in end time: anytime
Contactless check-in available
Minimum check-in age: 21

Check-out

Check-out before 11 AM
Contactless check-out available
Express check-out available

Special check-in instructions

Front desk staff will greet guests on arrival at the property
Information provided by the property may be translated using automated translation tools

Access methods

Staffed front desk

Pets

  • Service animals exempt from fees

Children and extra beds

  • Children 18 years old and younger stay free when using existing bedding
  • Free cribs/infant beds are available

Property payment types

Important information

Optional extras

These fees and deposits will be charged at check-in, check-out, or the time of service.

  • Nearby parking fee: USD 16.00 per day (500 ft away)

This list may not be comprehensive. Fees and deposits might not include tax and are subject to change.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
The name on the credit card used at check-in to pay for incidentals must be the primary name on the guestroom reservation
This property accepts credit cards; cash is not accepted
This property uses eco-friendly cleaning products
Safety features at this property include a smoke detector and window guards
This property affirms that it follows the cleaning and disinfection practices of Clean Promise (IHG)
Please note that cultural norms and guest policies may differ by country and by property; the policies listed are provided by the property
  • Check-in: 3:00 PM
  • Check-out: 11 AM
  • Minimum check-in age: 21
The front desk is open 24 hours a day, and checking out is easy with express services.

We should mention

Details about charges, deposits, or other important information:

  • This property is managed by a professional host. The provision of housing is linked to their trade, business, or profession.
  • Charges for extra guests may apply and vary depending on the property's policy.
  • A cash deposit, credit card, or debit card for incidental charges, as well as a government-issued photo ID, may be required at check-in.
  • Special requests are subject to availability at the time of check-in and can't be guaranteed. Certain requests may come with additional charges.
  • This property accepts credit cards. Cash is not accepted. 
  • The credit card used at check-in for incidentals must be in the name of the primary guest who made the reservation.
  • This property uses eco-friendly cleaning products.
  • Onsite safety features include a smoke detector and window guards.
  • This property affirms that it follows the cleaning and disinfection practices of Clean Promise (IHG).

Additional information about polices, regulations, and more:

  • Registered guests are the only ones allowed in guestrooms.
  • Connecting or adjoining rooms can be requested, but all rooms are subject to availability. Contact the property using the phone number on your booking confirmation.
  • No rollaway or extra beds are available.
  • This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly).

Property is also known as

Holiday Inn Express Buffalo Downtown Hotel
Comfort Suites Hotel Downtown
Comfort Suites Downtown Hotel Buffalo
Comfort Suites Downtown Buffalo
Comfort Suites Downtown Buffalo Hotel
Comfort Suites Buffalo
Buffalo Comfort Suites
Holiday Inn Express Buffalo Downtown
Holiday Inn Express Suites Buffalo Downtown
Holiday Inn Express Suites Buffalo Downtown Medical CTR
Holiday Inn Express Suites Buffalo Downtown Medical CTR by IHG

Frequently asked questions

Is free cancellation available at Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG?

Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG offers free cancellation on select room rates. For additional details, take a look at the cancellation policy on Orbitz.

How much does it cost to stay at Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG?

As of Dec 25, 2025, prices found for a 1-night stay for 2 adults at Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG on Dec 30, 2025 start from $118.0, excluding taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.

What is there to do close to Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG?

This hotel is situated in Downtown Buffalo, just steps from Shea's Performing Arts Center and Buffalo Music Hall of Fame, and within a short walk of Niagara Square. You'll also find Buffalo City Hall and Burt Flickinger Athletic Center less than a mile away.

Is there parking available at Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG?

Yes, there is accessible parking available.

Does Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG include a casino at the property?

No, Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG doesn't have a casino.

Is there an indoor pool at Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG?

No, there is no indoor pool at this hotel.

What amenities will couples enjoy at Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG?

Couples staying at this hotel will appreciate amenities like free breakfast and a 24-hour front desk plus some guestrooms include city views.

Are there hot tubs at Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG?

No, there isn't a spa tub at this hotel.

Does Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG have a restaurant that serves breakfast?

Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG offers free buffet breakfast each morning though there is no restaurant.

Does Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG allow pets to stay for free?

No, pets aren't allowed at Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG though service animals are welcome.

Are there connecting rooms at Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG?

Yes, you can book connecting guestrooms at this hotel for your group or family vacation.

Where is the closest airport to Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG?

The closest major airport to Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG is Buffalo Niagara Intl. Airport (BUF), which is 10.3 mi away (21 minutes by car). Another top airport is Niagara Falls, NY (IAG-Niagara Falls Intl.), which is located 22 mi away (30-minute drive).

Are there rooms with balconies that I can book at Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG?

No, you won't find guestrooms with balconies at Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG.

Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG Reviews

Reviews

8.6

Excellent

Rating 10 - Excellent. 561 out of 1006 reviews
Rating 8 - Good. 290 out of 1006 reviews
Rating 6 - Okay. 72 out of 1006 reviews
Rating 4 - Poor. 38 out of 1006 reviews
Rating 2 - Terrible. 45 out of 1006 reviews

9.0/10

Cleanliness

8.8/10

Staff & service

8.2/10

Amenities

8.6/10

Property conditions & facilities

8.4/10

Eco-friendliness

Reviews

10/10 Excellent

Kimberly

Business traveler
Liked: Cleanliness, staff & service, property conditions & facilities
Night staff was super friendly and welcoming! Rooms are spacious and comfortable
Stayed 1 night in Oct 2025

10/10 Excellent

JAMES

Traveled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Big suite comfy & well designed. Close in. Easy access to Theater District and all down Main to Canalside. Hreat comvention-going spoi. Plemty of room to store bikes in room. Good breakfast, same offerings every day
Stayed 5 nights in Sep 2025

4/10 Poor

Taylor

Stayed 1 night in Sep 2025

10/10 Excellent

Daryl

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Very simple yet comfortable rooms
Stayed 2 nights in Sep 2025

6/10 Okay

Matthew

Liked: Cleanliness, staff & service, amenities
Disliked: Property conditions & facilities
Clean, staff are nice and friendly. But the property itself is getting a little old and room had a very noisy rattle aircon that was kind of broken. Made it hard to sleep. The complimentary breakfast is good with enough options to start the day.
Stayed 3 nights in Sep 2025

10/10 Excellent

Raja

Traveled with family
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Aug 2025

2/10 Terrible

Tracey

They oversold Our room and we had to move
Stayed 1 night in Sep 2025

10/10 Excellent

LINDA

Traveled with group
Liked: Cleanliness, staff & service, amenities
Clean, large room. Nice bed
Stayed 1 night in Sep 2025

10/10 Excellent

Steven

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Great place to stay in Buffalo

It was a large room, with a nice king size bed. I liked that it had a fridge and microwave. I also liked the location in the theater district, very convenient.
Stayed 2 nights in Sep 2025

8/10 Good

Carl

Liked: Cleanliness, staff & service, property conditions & facilities
Stayed 3 nights in Sep 2025

8/10 Good

Michael

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 2 nights in Sep 2025

10/10 Excellent

Yevgeniya

Stayed 1 night in Sep 2025

10/10 Excellent

Joseph

Liked: Cleanliness, staff & service, property conditions & facilities
Great service
Stayed 1 night in Sep 2025

10/10 Excellent

Rocky

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Greats staff, room was great bed was perfect. Many hard drug users outside
Stayed 1 night in Sep 2025

8/10 Good

Angela

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Sep 2025

6/10 Okay

James

Liked: Cleanliness, property conditions & facilities
Disliked: Staff & service, room comfort

Planes, trains and automobiles

The room was next to the train, next to a road, and near the airport and there was nothing soundproofed, so it was loud for a lot of the evening. When I checked out, I was not asked a single question about our stay. Frankly, I felt completely dismissed. Normally this chain is really good, but our stay at this location is one that I will never do again.
Stayed 1 night in Aug 2025

8/10 Good

Vicki

Traveled with family
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
I thought I booked a room with 2 queen beds and I was told that this property only has King beds plus a pullout couch. The pullout couch was very uncomfortable. Otherwise, everything was clean, staff was very helpful with restaurant recommendations and the room was clean.
Stayed 1 night in Aug 2025

10/10 Excellent

Deborah

Liked: Cleanliness, staff & service, property conditions & facilities
Stayed 1 night in Aug 2025

10/10 Excellent

Lwin

Traveled with family
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Great
Stayed 1 night in Jul 2025

10/10 Excellent

Lelio

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Aug 2025

10/10 Excellent

Amber

Liked: Cleanliness, staff & service, property conditions & facilities
Perfect for what we were there for.
Stayed 1 night in Aug 2025

10/10 Excellent

Gustavo

Stayed 2 nights in Aug 2025

8/10 Good

Sylvia

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The hotel was well located and included a good breakfast. The room was big and comfortable. I think the hotel may need some minor maintenance, as towel holding rail was broken. But just minor things. I didn’t liked the parking. There is none on the hotel and you have to go few blocks to park
Stayed 1 night in Aug 2025

10/10 Excellent

benjamin

Traveled with family
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Wonderful hotel!!

Stayed 2 nights in Aug 2025

8/10 Good

Jessalynn

Traveled with family
Liked: Property conditions & facilities
The breakfast was exactly as expected The bed was wonderful
Stayed 1 night in Aug 2025