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Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG

2.5 star property

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Photo gallery for Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG

1 bedroom, in-room safe, desk, laptop workspace
Lobby sitting area
Free daily buffet breakfast
Business center
Lobby sitting area

Reviews

8.6 out of 10
Excellent

Popular amenities

  • Free WiFi
  • Air conditioning
  • Gym
  • Business services
  • Laundry

Explore the area

View in a map
601 Main St, Buffalo, NY, 14203
  • Place, Shea's Performing Arts Center
    ‪2 min walk‬
  • Place, Buffalo Niagara Convention Center
    ‪6 min walk‬
  • Place, Niagara Square
    ‪8 min walk‬
  • Airport, Buffalo, NY (BUF-Buffalo Niagara Intl.)
    ‪22 min drive‬

Room options

View all photos for Standard Room

Standard Room | 1 bedroom, in-room safe, desk, laptop workspace

Standard Room

9.2 out of 10
Wonderful
(26 reviews)
  • 500 sq ft
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed and 1 Double Sofa Bed
  • Free WiFi

View all photos for Suite, 1 Bedroom

Suite, 1 Bedroom | 1 bedroom, in-room safe, desk, laptop workspace

Suite, 1 Bedroom

8.8 out of 10
Excellent
(51 reviews)
  • City view
  • 500 sq ft
  • 1 bedroom
  • Sleeps 4
  • 1 King Bed
  • Free WiFi

View all photos for Suite, 1 Bedroom, Accessible (Mobility Accessible, Bathtub)

Combined shower/tub, eco-friendly toiletries, hair dryer, towels

Suite, 1 Bedroom, Accessible (Mobility Accessible, Bathtub)

9.6 out of 10
Exceptional
(4 reviews)
  • 500 sq ft
  • 1 bedroom
  • Sleeps 4
  • 1 Queen Bed
  • Free WiFi

View all photos for Suite, 1 Bedroom, Accessible (Mobility Accessible, Roll-in Shower)

Combined shower/tub, eco-friendly toiletries, hair dryer, towels

Suite, 1 Bedroom, Accessible (Mobility Accessible, Roll-in Shower)

9.0 out of 10
Wonderful
(4 reviews)
  • 500 sq ft
  • 1 bedroom
  • Sleeps 4
  • 1 Queen Bed
  • Free WiFi

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About the neighborhood

Buffalo

Located in Downtown Buffalo, Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG is next to popular attractions like Market Arcade Building and Buffalo Music Hall of Fame. This 146-room hotel welcomes guests with free breakfast and conveniences like free in-room WiFi and a gym.

What's nearby

  • Chippewa District - 1 min walk - 0.0 miles
  • Market Arcade Building - 1 min walk - 0.1 miles
  • Shea's Performing Arts Center - 2 min walk - 0.1 miles
  • Buffalo Niagara Convention Center - 6 min walk - 0.4 miles
  • Niagara Square - 8 min walk - 0.5 miles

Getting around

  • Fountain Plaza Station - 1 min walk
  • Buffalo-Exchange Street Station - 18 min walk
  • Buffalo Niagara Intl. Airport (BUF) - 21 min drive

Restaurants

  • ‪Big Ditch Brewing Company - ‬4 min walk
  • ‪Tap House Pub & Grill - ‬4 min walk
  • ‪Bada Bing - ‬2 min walk
  • ‪Eddie Brady's - ‬3 min walk
  • ‪Lucky Day Whiskey Bar - ‬4 min walk

About this property

Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG

Guests of Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG enjoy a gym, free WiFi in public areas, and a business center. Front-desk staff can answer questions 24/7, and assist with luggage storage, securing valuables, and dry cleaning/laundry. Additional amenities include express check-out, laundry facilities, and a vending machine.
Guests can expect free WiFi and 49-inch TVs with cable channels. Bathrooms have hair dryers and free toiletries. Other amenities include sofa beds, sitting areas, and refrigerators.
Recreational amenities at the hotel include a fitness center.

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Property amenities

Internet

  • Available in all rooms: Free WiFi
  • Available in some public areas: Free WiFi

Parking and transportation

  • Offsite parking available (USD 16 per day)
  • Wheelchair-accessible parking and van parking available
  • Onsite parking options include a garage

Food and drink

  • Free buffet breakfast available daily 6:00 AM to 10:00 AM

Things to do

  • Gym

Family friendly

  • In-room crib
  • In-room microwave
  • In-room refrigerator
  • In-room sofa bed
  • Laundry facilities
  • Living room
  • Separate bedroom

Conveniences

  • 24-hour front desk
  • Guidebooks
  • Laundry facilities
  • Luggage storage
  • Safe at front desk
  • Vending machine

Guest services

  • Dry cleaning/laundry service
  • Housekeeping (daily)

Business services

  • Business center

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Assistive listening devices
  • Elevator
  • Grab bar in shower
  • Grab bar near toilet
  • Hand-held showerhead
  • Handrails in stairways
  • Height-adjustable showerhead
  • In-room roll-in shower
  • Lever door handles
  • Low-height electrical outlets in bathroom
  • Portable shower seat
  • Raised toilet seat
  • Visual fire alarm
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible bathroom vanity
  • Wheelchair-accessible business center
  • Wheelchair-accessible gym
  • Wheelchair-accessible parking
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible path to elevator
  • Wheelchair-accessible public washroom
  • Wheelchair-accessible registration desk
  • Wheelchair-accessible restaurant
  • Wheelchair-accessible van parking

More

  • 7 floors
  • At least 80% lighting from LEDs
  • Comprehensive food waste policy
  • Eco-friendly cleaning products used
  • Smoking not allowed
  • Vegetarian breakfast available
  • Vegetarian dining options

Room amenities

Bedroom

  • Bedsheets provided
  • Blackout drapes
  • Double sofa bed
  • Free crib

Bathroom

  • Free toiletries
  • Hair dryer
  • Private bathroom
  • Shower/bathtub combination
  • Towels provided

Entertainment

  • 49-inch TV with cable channels

Food and drink

  • Coffee/tea maker
  • Microwave
  • Refrigerator
  • Restaurant dining guides

More

  • Air conditioning (climate-controlled)
  • Bulk dispensers for toiletries
  • Connecting rooms available
  • Desk
  • Eco-friendly toiletries
  • Free local calls
  • Heating
  • Iron/ironing board
  • Laptop workspace
  • LED lighting
  • Living room
  • Phone
  • Safe
  • Separate sitting area

Policies

Check-in

Check-in start time: 3:00 PM; Check-in end time: anytime
Contactless check-in available
Minimum check-in age: 21

Check-out

Check-out before 11 AM
Contactless check-out available
Express check-out available

Special check-in instructions

Front desk staff will greet guests on arrival at the property
Information provided by the property may be translated using automated translation tools

Access methods

Staffed front desk

Pets

  • Service animals exempt from fees

Children and extra beds

  • Children 18 years old and younger stay free when using existing bedding
  • Free cribs/infant beds are available

Property payment types

Important information

Optional extras

These fees and deposits will be charged at check-in, check-out, or the time of service.

  • Nearby parking fee: USD 16.00 per day (500 ft away)

This list may not be comprehensive. Fees and deposits might not include tax and are subject to change.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
The name on the credit card used at check-in to pay for incidentals must be the primary name on the guestroom reservation
This property accepts credit cards; cash is not accepted
This property uses eco-friendly cleaning products
Safety features at this property include a fire extinguisher, a smoke detector, and window guards
This property affirms that it follows the cleaning and disinfection practices of Clean Promise (IHG)
Please note that cultural norms and guest policies may differ by country and by property; the policies listed are provided by the property
  • Check-in: 3:00 PM
  • Check-out: 11 AM
  • Minimum check-in age: 21
The front desk is open 24 hours a day, and checking out is easy with express services.

We should mention

Details about charges, deposits, or other important information:

  • This property is managed by a professional host. The provision of housing is linked to their trade, business, or profession.
  • Charges for extra guests may apply and vary depending on the property's policy.
  • A cash deposit, credit card, or debit card for incidental charges, as well as a government-issued photo ID, may be required at check-in.
  • Special requests are subject to availability at the time of check-in and can't be guaranteed. Certain requests may come with additional charges.
  • This property accepts credit cards. Cash is not accepted. 
  • The credit card used at check-in for incidentals must be in the name of the primary guest who made the reservation.
  • This property uses eco-friendly cleaning products.
  • Onsite safety features include a fire extinguisher, a smoke detector, and window guards.
  • This property affirms that it follows the cleaning and disinfection practices of Clean Promise (IHG).

Additional information about polices, regulations, and more:

  • Registered guests are the only ones allowed in guestrooms.
  • Connecting or adjoining rooms can be requested, but all rooms are subject to availability. Contact the property using the phone number on your booking confirmation.
  • No rollaway or extra beds are available.
  • This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly).

Property is also known as

Holiday Inn Express Buffalo Downtown Hotel
Comfort Suites Hotel Downtown
Comfort Suites Downtown Hotel Buffalo
Comfort Suites Downtown Buffalo
Comfort Suites Downtown Buffalo Hotel
Comfort Suites Buffalo
Buffalo Comfort Suites
Holiday Inn Express Buffalo Downtown
Holiday Inn Express Suites Buffalo Downtown
Holiday Inn Express Suites Buffalo Downtown Medical CTR
Holiday Inn Express Suites Buffalo Downtown Medical CTR by IHG

Frequently asked questions

Is free cancellation available at Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG?

Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG offers free cancellation on select room rates. For additional details, take a look at the cancellation policy on Orbitz.

How much does it cost to stay at Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG?

As of May 11, 2026, prices found for a 1-night stay for 2 adults at Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG on May 31, 2026 start from $153, including taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.

What is there to do close to Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG?

This hotel is situated in Downtown Buffalo, just steps from Shea's Performing Arts Center and Buffalo Music Hall of Fame, and within a short walk of Niagara Square. You'll also find KeyBank Center and Lake Erie within a short drive.

Will I be able to park at Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG?

Yes, there is wheelchair-accessible van parking available.

Does Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG include a casino at the property?

No, Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG doesn't have a casino.

Is there an indoor pool at Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG?

No, there is no indoor pool at this hotel.

Is Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG good for couples?

Couples staying at this hotel will appreciate amenities like a free daily breakfast plus some guestrooms include a city view and free WiFi.

Are there hot tubs at Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG?

No, there isn't a spa tub at this hotel.

Does Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG have a restaurant that serves breakfast?

Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG offers free buffet breakfast each morning though there is no restaurant.

Does Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG allow pets to stay for free?

No, pets aren't allowed at Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG though service animals are welcome.

Are there connecting rooms at Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG?

Yes, this hotel has connecting rooms you can book for your group event or vacation.

Where is the closest airport to Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG?

The closest major airport to Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG is Buffalo Niagara Intl. Airport (BUF), which is 10.3 mi away (21 minutes by car). Another top airport is Niagara Falls, NY (IAG-Niagara Falls Intl.), which is located 22 mi away (30-minute drive).

Can I book a room with a balcony at Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG?

No, you won't find guestrooms with balconies at Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG.

Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG Reviews

Reviews

8.6

Excellent

Rating 10 - Excellent. 566 out of 1008 reviews
Rating 8 - Good. 274 out of 1008 reviews
Rating 6 - Okay. 74 out of 1008 reviews
Rating 4 - Poor. 41 out of 1008 reviews
Rating 2 - Terrible. 53 out of 1008 reviews

8.8/10

Cleanliness

8.8/10

Staff & service

8.2/10

Amenities

8.6/10

Property conditions & facilities

Reviews

4/10 Poor

Stacey, Corning

Traveled with group
Disliked: Cleanliness, staff & service
Wasn't impressed with the woman handing my check in. Elevator walls were disgusting. Disappointing for a Holiday Inn.
Stayed 1 night in Feb 2026

2/10 Terrible

Grace

Stayed 1 night in Jan 2026

8/10 Good

Catherine

Liked: Amenities, property conditions & facilities
Staff
Stayed 1 night in Feb 2026

6/10 Okay

Lee

Liked: Staff & service
Staff very good. Hotel quite worn in parts; i.e getting random electric shocks from door handles and light switches. Food smell in room everytime fans active (food hall next door). Beds comfy and plenty of space in room/suite. Complimentary breakfast okay with fairly small choice. A fair price for what we paid considering nearby alternatives were more expensive and we were located near numerous bars and restaurants.
Stayed 4 nights in Feb 2026

6/10 Okay

Amber

Stayed 2 nights in Feb 2026

10/10 Excellent

NaDav-ya

Stayed 1 night in Feb 2026

10/10 Excellent

Ellen

Liked: Cleanliness, staff & service, amenities
Very clean and friendly staff
Stayed 1 night in Feb 2026

10/10 Excellent

Julie

Traveled with partner
Liked: Cleanliness, amenities, property conditions & facilities
Beautiful room clean most comfortable bed I have ever slept in!
Stayed 1 night in Jan 2026

2/10 Terrible

MASAHIRO

Business traveler
Liked: Cleanliness, amenities, property conditions & facilities
When I checked out, I paid for my stay with a credit card at the front desk, but requested a receipt, which was refused. I was on a business trip, but without a receipt, I cannot settle the expenses. The hotel must immediately send me a receipt by email. If they refuse, I will not hesitate to sue them.
Stayed 3 nights in Feb 2026

4/10 Poor

Justin

Traveled with partner
Room was dark. Fire alarm went off at 5 am.
Stayed 1 night in Feb 2026

4/10 Poor

Robert

Traveled with partner, Traveled with family
Disliked: Cleanliness, amenities, property conditions & facilities
Upon arrival the first room Ingotnto had not been cleaned or serviced. When I notified the front deak she told me thats why she doesnt like checking people in early with a clear attititude. The overall appearance and cleanliness of the hotel was sub par, even by holiday inn express standards.
Stayed 1 night in Jan 2026

10/10 Excellent

Eden

Liked: Cleanliness, amenities, property conditions & facilities
Very clean and friendly
Stayed 1 night in Feb 2026

2/10 Terrible

Stephanie

Disliked: Cleanliness, amenities, property conditions & facilities
Very disappointing stay. At check-in, the front desk agent was distracted and unprofessional, carrying on another conversation while helping me. The room keys didn’t work, and I had to go back and forth to the front desk multiple times, waiting in long lines each time. It took about 45 minutes just to get into my room, which made me late when I already had somewhere to be. Once inside, the room clearly wasn’t properly cleaned—there were other guests’ hair products on the floor, a hole in the door, and the toilet wouldn’t flush unless you tried several times. Overall, one of the worst hotel experiences I’ve had. Would not recommend.
Stayed 1 night in Jan 2026

4/10 Poor

Kaylee

Traveled with partner
Liked: Cleanliness
Disliked: Amenities, property conditions & facilities
Check in was terrible, keys didn’t work, staff barely batted an eye at me, rude staff, wifi was terrible, no option for early check in, parking too far away
Stayed 1 night in Jan 2026

10/10 Excellent

Theron

Big, spacious room and suite. Excellent location
Stayed 1 night in Feb 2026

8/10 Good

Jennifer

Stayed 1 night in Nov 2025

10/10 Excellent

Richard

Stayed 1 night in Feb 2026

10/10 Excellent

Bryan

Stayed 1 night in Jan 2026

10/10 Excellent

Charles

Liked: Cleanliness, property conditions & facilities
No parking is not a good thing
Stayed 1 night in Jan 2026

10/10 Excellent

Mallory

Traveled with partner
Liked: Cleanliness, property conditions & facilities
The room was great and spacious
Stayed 1 night in Jan 2026

10/10 Excellent

Joseph

Liked: Cleanliness, amenities, property conditions & facilities
Great service and great location
Stayed 1 night in Jan 2026

2/10 Terrible

William

Disliked: Cleanliness, staff & service, amenities
This has got to be the worst place I've ever stayed in , rude staff and no help what's o ever , I will never stay here again let alone a holiday in in the near future .. dirty room and parking is 2 blocks away
Stayed 1 night in Jan 2026

10/10 Excellent

Camryn

Stayed 1 night in Jan 2026

10/10 Excellent

Shauna

Stayed 1 night in Jan 2026

10/10 Excellent

Paul

Traveled with group
Liked: Cleanliness, amenities, property conditions & facilities
The room was clean, the staff were AMAZING, especially Mario and Eddie on the front desk!!! I cannot say how incredible the overall experience was. Would highly recommend
Stayed 1 night in Jan 2026