Hotels in Wykoff
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Top Rated Wykoff Hotels

Kahler Grand Hotel
20 2nd Ave Sw Rochester MN
Free Cancellation
Reserve now, pay when you stay
23.95 mi from city center
$149 nightly
The price is $172 total per night
$172 total
Dec 28 - Dec 29
Total with taxes and fees
At Kahler Grand Hotel, guests enjoy features like an indoor pool, a 24-hour gym, and a sauna. Valet parking is offered for USD 30.00 per day. The front desk has multilingual staff on hand 24/7 to help with luggage storage, dry cleaning/laundry, and securing valuables. Additional amenities include free WiFi in public areas, a hot tub, and meeting rooms.
Pool
Hot Tub

Kahler Inn and Suites - Mayo Clinic Area
9 3rd Ave Nw Rochester MN
Free Cancellation
Reserve now, pay when you stay
24.03 mi from city center
$155 nightly
The price is $178 total per night
$178 total
Dec 28 - Dec 29
Total with taxes and fees
Guests staying at Kahler Inn and Suites - Mayo Clinic Area enjoy an indoor pool, a gym, and free WiFi in public areas. Self parking is offered for USD 15 per night. The 24-hour front desk has staff always at the ready. Additional amenities include laundry facilities, a TV in a common area, and a water dispenser.
Pool
Breakfast included

Hampton Inn Rochester-South
1755 S Broadway Rochester MN
Free Cancellation
Reserve now, pay when you stay
22.22 mi from city center
$81 nightly
The price is $93 total per night
$93 total
Jan 24 - Jan 25, 2026
Total with taxes and fees
Guests of Hampton Inn Rochester-South have access to an indoor pool, a 24-hour gym, and free WiFi in public areas. You can take advantage of free parking, along with a free area shuttle. The front desk is staffed 24/7 to help with dry cleaning/laundry, concierge services, and luggage storage. Additional amenities include a hot tub, a 24-hour business center, and coffee/tea in a common area.
Pool
Hot Tub

Spark by Hilton Rochester South
4165 Maine Ave SE Rochester MN
Free Cancellation
Reserve now, pay when you stay
19.88 mi from city center
$71 nightly
The price is $81 total per night
$81 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
Guests staying at Spark by Hilton Rochester South enjoy an indoor pool, a gym, and free WiFi in public areas. You can take advantage of free parking, along with a free area shuttle. The 24-hour front desk has staff standing by to help with luggage storage, securing valuables, and dry cleaning/laundry. Additional amenities include conference space, a 24-hour business center, and coffee/tea in a common area.
Pool
Breakfast included

Hotel Indigo Rochester – Mayo Clinic Area by IHG
220 S Broadway Rochester MN
Free Cancellation
23.74 mi from city center
$77 nightly
The price is $89 total per night
$89 total
Jan 24 - Jan 25, 2026
Total with taxes and fees
Hotel Indigo Rochester – Mayo Clinic Area by IHG offers a gym, a rooftop terrace, and free WiFi in public areas. Self parking is available for USD 16.00 per night. Front-desk staff can answer questions 24/7, and assist with luggage storage, securing valuables, and dry cleaning/laundry. Additional amenities include meeting rooms, conference space, and a 24-hour business center.
Pet friendly
Free WiFi

Hyatt House Rochester/Mayo Clinic Area
110 Civic Center Drive NW Rochester MN
Free Cancellation
Reserve now, pay when you stay
24.15 mi from city center
$129 nightly
The price is $149 total per night
$149 total
Dec 28 - Dec 29
Total with taxes and fees
Guests staying at Hyatt House Rochester/Mayo Clinic Area enjoy an indoor pool, a gym, and free WiFi in public areas. If you drive, self parking is USD 16 per day, and there's also a free area shuttle. The front desk is staffed 24/7 to help with luggage storage, dry cleaning/laundry, and securing valuables. Additional amenities include a hot tub, conference space, and a 24-hour business center.
Pool
Hot Tub

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
4353 Canal Pl SE Rochester MN
Free Cancellation
Reserve now, pay when you stay
19.89 mi from city center
$71 nightly
The price is $82 total per night
$82 total
Dec 28 - Dec 29
Total with taxes and fees
At La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S, guests have access to a gym, free WiFi in public areas, and meeting rooms. There's free parking if you drive. The front desk is staffed 24 hours a day to help with luggage storage and securing valuables. Additional amenities include conference space, a 24-hour business center, and coffee/tea in a common area.
Pool
Breakfast included

EVEN Hotel Rochester - Mayo Clinic Area by IHG
101 11TH Avenue SW Rochester MN
Free Cancellation
24.15 mi from city center
$99 nightly
The price is $114 total per night
$114 total
Dec 28 - Dec 29
Total with taxes and fees
At EVEN Hotel Rochester - Mayo Clinic Area by IHG, guests enjoy an indoor pool, a 24-hour gym, and free WiFi in public areas. Self parking is offered for USD 20 per night. The 24-hour front desk has multilingual staff ready to assist with dry cleaning/laundry and securing valuables. Additional amenities include a hot tub, conference space, and a 24-hour business center.
Pool
Hot Tub

Aspen Suites
1211 2nd Street Rochester MN
Free Cancellation
Reserve now, pay when you stay
24.18 mi from city center
$152 nightly
The price is $175 total per night
$175 total
Dec 28 - Dec 29
Total with taxes and fees
Guests of Aspen Suites have access to an indoor pool, a gym, and free WiFi in public areas. There's free parking and a free area shuttle. The front desk is staffed 24/7 to help with dry cleaning/laundry, securing valuables, and concierge services. Additional amenities include a hot tub, a 24-hour business center, and coffee/tea in a common area.
Pool
Hot Tub

AmericInn by Wyndham Rochester Near Mayo Clinic
1625 Broadway Ave S Rochester MN
Free Cancellation
Reserve now, pay when you stay
22.41 mi from city center
$74 nightly
The price is $85 total per night
$85 total
Jan 2 - Jan 3, 2026
Total with taxes and fees
AmericInn by Wyndham Rochester Near Mayo Clinic features a full-service spa, an indoor pool, and a children's pool. You can take advantage of free parking, along with an area shuttle. The 24-hour front desk has multilingual staff ready to help with luggage storage, and answer any questions about the area. Other amenities at this spa hotel include a 24-hour gym, free WiFi in public areas, and a hot tub.
Pool
Hot Tub

The Berkman
217 14th Ave SW Rochester MN
Free Cancellation
Reserve now, pay when you stay
24.2 mi from city center
$188 nightly
The price is $216 total per night
$216 total
Dec 28 - Dec 29
Total with taxes and fees
The Berkman offers a gym, a rooftop terrace, and free WiFi in public areas. If you drive, self parking is USD 20.00 per night, or you can take advantage of the airport shuttle (available 24 hours) for USD 49 per person one-way. Front-desk staff can answer questions 24/7, and assist with tours or tickets, dry cleaning/laundry, and securing valuables. If you like to take your furry friend along on your adventures, this pet-friendly property offers an off-leash area. Other amenities at this golf aparthotel include a 24-hour business center, a seasonal outdoor pool, and an arcade/game room.
Pool
Kitchen

SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys
1125 2nd St Sw Rochester MN
Free Cancellation
Reserve now, pay when you stay
24.17 mi from city center
$94 nightly
The price is $108 total per night
$108 total
Jan 2 - Jan 3, 2026
Total with taxes and fees
Guests staying at SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys enjoy an indoor pool, a 24-hour gym, and free WiFi in public areas. Free parking is included with your stay. The front desk is staffed 24 hours a day to help with securing valuables and dry cleaning/laundry. Additional amenities include a hot tub, a 24-hour business center, and a computer station.
Pool
Hot Tub
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where is a good place to stay in Wykoff?
What are some of the best hotels in Wykoff?
Here are some top hotels around Wykoff:
- Kahler Grand Hotel is located 24 mi away, and this hotel has 2 restaurants, free WiFi, and a 24-hour fitness center.
- Kahler Inn and Suites - Mayo Clinic Area is located 24 mi away, and this hotel has free breakfast, free WiFi, and a fitness center.
- Hampton Inn Rochester-South is located 22.2 mi away, and this hotel has free breakfast, free WiFi, and free parking.
What are the best hotels to stay near Ed's Museum?
You'll find fun all over the place in Wykoff, starting with Ed's Museum. This well-known museum is just 1 mile from the downtown area and on the hit list of many travelers. Love to stay within easy reach of it? You sure can. Friendly-farm Retreat is 1 mile away and a terrific option.
Wykoff hotels essential information
Accommodation | 324 hotels |
|---|---|
Lowest Price | $81 |
Highest Price | $216 |
Popular hotels | Kahler Grand Hotel, Kahler Inn and Suites - Mayo Clinic Area, Hampton Inn Rochester-South, Spark by Hilton Rochester South, Hotel Indigo Rochester – Mayo Clinic Area by IHG, Hyatt House Rochester/Mayo Clinic Area, La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S, EVEN Hotel Rochester - Mayo Clinic Area by IHG, Aspen Suites, AmericInn by Wyndham Rochester Near Mayo Clinic, The Berkman, SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys |
Recent Reviews

Hotel Indigo Rochester – Mayo Clinic Area by IHG
5/5 Excellent
"The room was perfect clean and absolutely perfect "
A verified traveler stayed at Hotel Indigo Rochester – Mayo Clinic Area by IHG
Posted 15 hours ago
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