Hotels in Midtown
Earn Orbucks instantly: $1 Orbuck = $1 USD, good toward hotels
Save 10% or more on select hotels with Insider Prices
Book on the app to instantly earn 5% on 350,000+ hotels
Featured Hotels in Midtown

Element St. Louis Midtown
3763 Forest Park Avenue St. Louis MO
Free Cancellation
Reserve now, pay when you stay
0.74 mi from Midtown
$135 nightly
The price is $158 total per night
$158 total
Mar 30 - Mar 31
Total with taxes and fees
Guests of Element St. Louis Midtown have access to an indoor pool, a 24-hour gym, and free WiFi in public areas. Valet parking is available for USD 28 per day. The 24-hour front desk has staff standing by to help with securing valuables and luggage storage. If you like to take your furry friend along on your adventures, this pet-friendly property offers food and water bowls. Additional amenities include meeting rooms, free use of bicycles, and a computer station.
Pool
Breakfast included

Residence Inn by Marriott St Louis Downtown
525 S Jefferson Ave St. Louis MO
Free Cancellation
Reserve now, pay when you stay
0.57 mi from Midtown
$101 nightly
The price is $120 total per night
$120 total
Apr 1 - Apr 2
Total with taxes and fees
Guests of Residence Inn by Marriott St Louis Downtown enjoy a 24-hour gym, free WiFi in public areas, and conference space. Self parking is offered for USD 28 per day. The 24-hour front desk has staff standing by to help with dry cleaning/laundry, luggage storage, and securing valuables. Additional amenities include a 24-hour business center, a computer station, and express check-in.
Pet friendly
Free WiFi

Pear Tree Inn St. Louis Near Union Station
2211 Market Street St. Louis MO
Free Cancellation
Reserve now, pay when you stay
0.78 mi from Midtown
$106 nightly
The price is $124 total per night
$124 total
Apr 5 - Apr 6
Total with taxes and fees
Guests of Pear Tree Inn St. Louis Near Union Station have access to an indoor pool, a gym, and free WiFi in public areas. You can take advantage of free parking if you drive. The 24-hour front desk has staff standing by to help with securing valuables, dry cleaning/laundry, and luggage storage. Additional amenities include a hot tub, meeting rooms, and a business center.
Pool
Hot Tub

21C Museum Hotel St Louis
1528 Locust street St. Louis MO
Free Cancellation
Reserve now, pay when you stay
1.29 mi from Midtown
$131 nightly
The price is $153 total per night
$153 total
Apr 5 - Apr 6
Total with taxes and fees
Guests of 21C Museum Hotel St Louis have access to an indoor pool, a gym, and a steam room. Valet parking is offered for USD 50 per day. The front desk is staffed 24/7 to help with concierge services, dry cleaning/laundry, and luggage storage. Other amenities at this luxury hotel include free WiFi in public areas, meeting rooms, and a business center.
Pool
Spa

Drury Plaza Hotel St. Louis at the Arch
2 South 4th Street St. Louis MO
Free Cancellation
Reserve now, pay when you stay
2.1 mi from Midtown
$150 nightly
The price is $175 total per night
$175 total
Mar 16 - Mar 17
Total with taxes and fees
Guests of Drury Plaza Hotel St. Louis at the Arch have access to an indoor pool, a gym, and 2 hot tubs. The 24-hour front desk has staff standing by to help with dry cleaning/laundry, luggage storage, and securing valuables. Additional amenities include free WiFi in public areas, conference space, and a business center.
Pool
Hot Tub

Hyatt Regency St. Louis at The Arch
315 Chestnut St St. Louis MO
2.13 mi from Midtown
$169 nightly
The price is $199 total per night
$199 total
Mar 23 - Mar 24
Total with taxes and fees
Guests staying at Hyatt Regency St. Louis at The Arch enjoy a gym, a rooftop terrace, and free WiFi in public areas. Parking is available for USD 40 per night (USD 50 per day for valet parking), and there's also limo/town car service. The 24-hour front desk has multilingual staff ready to assist with dry cleaning/laundry, concierge services, and luggage storage. Additional amenities include meeting rooms, conference space, and a 24-hour business center.
Pet friendly
Free WiFi

Clayton Plaza Hotel & Extended Stay
7750 Carondelet Avenue St. Louis MO
Free Cancellation
Reserve now, pay when you stay
6.06 mi from Midtown
$99 nightly
The price is $116 total per night
$116 total
Mar 22 - Mar 23
Total with taxes and fees
Guests of Clayton Plaza Hotel & Extended Stay have access to an indoor pool, a 24-hour gym, and a sauna. Self parking is offered for USD 6.00 per night. Front-desk staff can answer questions 24/7, and assist with securing valuables, luggage storage, and dry cleaning/laundry. Additional amenities include free WiFi in public areas, meeting rooms, and conference space.
Pool
Breakfast included

River City Casino & Hotel
777 River City Casino Blvd St. Louis MO
7.39 mi from Midtown
$99 nightly
The price is $115 total per night
$115 total
Apr 9 - Apr 10
Total with taxes and fees
River City Casino & Hotel features a casino, a nightclub, and a 24-hour gym. If you plan to drive, free parking is available. The front desk is staffed 24/7 to help with tours or tickets, securing valuables, and luggage storage. Additional amenities include a conference center, a business center, and express check-out.
Parking included
Restaurant

Hollywood Casino & Hotel St. Louis
777 Casino Center Drive Maryland Heights MO
Free Cancellation
Reserve now, pay when you stay
16.01 mi from Midtown
$106 nightly
The price is $124 total per night
$124 total
Apr 1 - Apr 2
Total with taxes and fees
Guests of Hollywood Casino & Hotel St. Louis have access to a casino, a 24-hour gym, and meeting rooms. You can take advantage of free parking, along with a free airport shuttle at scheduled times. Front-desk staff can answer questions 24/7, and assist with luggage storage, concierge services, and securing valuables. Additional amenities include conference space, a 24-hour business center, and express check-out.
Free airport shuttle
Parking included
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Midtown hotels essential information
Accommodation | 1,898 hotels |
|---|---|
Lowest Price | $115 |
Highest Price | $199 |
Popular hotels | Element St. Louis Midtown, Residence Inn by Marriott St Louis Downtown, Drury Plaza Hotel St. Louis at the Arch, Pear Tree Inn St. Louis Near Union Station, Clayton Plaza Hotel & Extended Stay, 21C Museum Hotel St Louis , Hollywood Casino & Hotel St. Louis, Hyatt Regency St. Louis at The Arch, River City Casino & Hotel |
Popular places to visit

St. Louis University
Explore the campus of St. Louis University as part of your travels around St. Louis. Wander around the area's picturesque gardens or experience its fascinating museums.
Chaifetz Arena
Catch an event at Chaifetz Arena during your trip to St. Louis. Amble around the area's picturesque gardens or attend a baseball game.
Samuel Cupples House
You can learn about the history of St. Louis with a stop at Samuel Cupples House. Experience the area's acclaimed art scene or attend a sporting event.
Recent Reviews

Drury Plaza Hotel St. Louis at the Arch
5/5 Excellent
"Great place to stay right next to Gateway Arch National Park. Walkable to other downtown points of interest as well. The happy hour drinks and dinner was a great bonus. Would stay again."
A verified traveler stayed at Drury Plaza Hotel St. Louis at the Arch
Posted 2 hours ago
More to Explore
- Hotels with an Indoor Pool in St. Louis
- Hotels near Dome at America’s Center
- Hotels near Gateway Arch
- Hotels with Free Airport Shuttle in St. Louis
- Hotels near St. Louis University
- Hotels in Downtown St. Louis
- Car rentals in St. Louis
- Hotels near Enterprise Center
- Casinos in St. Louis
- Flights to St. Louis
- Hotels with Hot Tubs in St. Louis
- Hotels near Busch Stadium
- Hotels in St. Louis
- Cheap Hotels in St. Louis
- Hotels near America's Center Convention Complex
- Motels in St. Louis
- St. Louis vacations
- Pet-friendly Hotels in St. Louis
- Hotels near St. Louis Union Station


