
Package deals near Mayo Clinic Florida
Save more on your trip when booking your flight + hotel together
Top Mayo Clinic Florida vacation deals

Legacy Vacation Resorts Palm Coast
Aug 22 - Aug 25
New York (NYC) to Daytona Beach (DAB)
Daytona Beach (DAB) to New York (NYC)
Reviewed on Apr 21, 2024



The Villas of Amelia Island
Oct 2 - Oct 8
Dallas (DFW) to Jacksonville (JAX)
Jacksonville (JAX) to Dallas (DFW)
Reviewed on Sep 28, 2024

Hammock Beach Golf Resort & Spa
Aug 27 - Sep 1
Dallas (DFW) to Daytona Beach (DAB)
Reviewed on Apr 21, 2025

Margaritaville Jacksonville Beach
Sep 24 - Sep 28
Dallas (DFW) to Jacksonville (JAX)
Jacksonville (JAX) to Dallas (DFW)
Reviewed on Jul 1, 2025
Hotel deals near Mayo Clinic Florida

Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches

Residence Inn By Marriott Jacksonville - Mayo Clinic Area

Margaritaville Jacksonville Beach
Book a Mayo Clinic Florida vacation package
Stop dreaming and start traveling. If you’ve always wanted to see Mayo Clinic Florida, now is the perfect time. Book your getaway to Jacksonville with Orbitz and get ready to tick this attraction off your bucket list. Plus when you lock in your package with us, you’ll have plenty of cash leftover to splash out on other amazing Jacksonville sights. Because travel is all about investing in experiences, not things!
If you’re hoping to stay close to Mayo Clinic Florida, we’ve got you covered. Choose from a great range of hotels not far from this attraction. Roll out of bed, slip on your walking shoes and you’ll be there within moments. What could be more convenient than that? You won’t just be close to all the action — you’ll save money on transportation, and a hot shower and cozy bed will be within reach after a big day of exploring. Now that’s what we call a stress- free, full-of-fun getaway.
Orbitz has your ticket to a rewarding Mayo Clinic Florida vacation. Book your Jacksonville package with us and you’ll be able to access Orbitz Rewards. Earn Orbucks when you reserve your flights, hotels and activities with Orbitz and redeem them at over 385,000 hotels worldwide. $1 Orbuck = $1 off your next hotel. Join, earn, redeem — just like that! When you join Orbitz Rewards, you’ll also instantly unlock exclusive deals and save on thousands of properties with Insider Pricing.
We believe the best reward that you can give to yourself or others is the gift of travel. So, don’t put off exploring Mayo Clinic Florida any longer. Save a bundle and book your Jacksonville escape with Orbitz today.
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^Savings based on all package bookings with Flight + Hotel made on Orbitz.com from 2019-04-01 - 2020-03-31 as compared to the price of the same components booked separately. Savings will vary based on origin/destination, length of trip, stay dates and selected travel supplier(s). Savings not available on all packages.