$193 Cheap flights to Santa Cruz

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Cheap flights to Santa Cruz from $193 One Way, $397 Round Trip

$397 return flights and $193 one-way flights to Santa Cruz were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sat, Nov 8 - Fri, Nov 14
MIA
Miami
VVI
Santa Cruz
$397 Roundtrip, found 8 hours ago
$397
Roundtrip
found 8 hours ago
Select Copa flight, departing Sat, Nov 8 from Miami to Santa Cruz, returning Fri, Nov 14, priced at $397 found 8 hours ago
Sat, Nov 15 - Mon, Nov 24
FLL
Fort Lauderdale
VVI
Santa Cruz
$435 Roundtrip, found 1 hour ago
$435
Roundtrip
found 1 hour ago
Select avianca flight, departing Sat, Nov 15 from Fort Lauderdale to Santa Cruz, returning Mon, Nov 24, priced at $435 found 1 hour ago
Wed, Oct 29 - Sun, Nov 2
MIA
Miami
VVI
Santa Cruz
$435 Roundtrip, just found
$435
Roundtrip
just found
Select avianca flight, departing Wed, Oct 29 from Miami to Santa Cruz, returning Sun, Nov 2, priced at $435 just found
Thu, Oct 30 - Sat, Nov 1
IAD
Washington
VVI
Santa Cruz
$442 Roundtrip, found 4 days ago
$442
Roundtrip
found 4 days ago
Select Copa flight, departing Thu, Oct 30 from Washington to Santa Cruz, returning Sat, Nov 1, priced at $442 found 4 days ago
Tue, Nov 4 - Thu, Nov 6
JFK
New York
VVI
Santa Cruz
$455 Roundtrip, found 3 days ago
$455
Roundtrip
found 3 days ago
Select avianca flight, departing Tue, Nov 4 from New York to Santa Cruz, returning Thu, Nov 6, priced at $455 found 3 days ago
Wed, Oct 29 - Sun, Nov 2
DFW
Dallas
VVI
Santa Cruz
$499 Roundtrip, found 2 hours ago
$499
Roundtrip
found 2 hours ago
Select avianca flight, departing Wed, Oct 29 from Dallas to Santa Cruz, returning Sun, Nov 2, priced at $499 found 2 hours ago

Deals For This Weekend's Flights

OriginDestinationTravel DatesFlights From*
IADSanta CruzOctober 18 to November 2$490
IADSanta CruzOctober 18 to November 2$490
MIASanta CruzOctober 19 to November 2$576
JFKSanta CruzOctober 17 to October 27$581
LAXSanta CruzOctober 18 to December 18$788
MADSanta CruzOctober 19 to December 25$1,193
*Prices include taxes and fees

Find The Perfect Hotel For After Your Flight

Score Epic Santa Cruz Accommodation Deals

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

3.5 out of 5
Ave. San Martin, #455, Santa Cruz
$118 nightly
The price is $118 total per night from Oct 18 to Oct 19
$118 total
Oct 18 - Oct 19
Stay at this 3.5-star spa hotel in Santa Cruz. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular ...
8.8/10 Excellent! (331 reviews)
"Hotel was excellent. Staff excellent, check in good and bar resturant really good. room was good and clean"

Reviewed on Oct 3, 2025

Opens in a new windowLos Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
Hotel LP Equipetrol

Hotel LP Equipetrol

3.5 out of 5
Dr Victor Pinto, Equipetrol, esquina Marcelo Terceros Banzer, Santa Cruz
Stay at this 3.5-star hotel in Santa Cruz. Enjoy free WiFi, breakfast (surcharge), and room service. Popular attractions Ventura Mall and Santa Cruz Zoo are ...
8/10 Very Good! (200 reviews)
"So, the mattress and pillows were not that comfortable, hard. No microwave and the sheets not the size of the bed, smaller. The treatment from the hotel personnel was good."

Reviewed on Feb 21, 2025

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Opens in a new windowHotel LP Equipetrol
Yotau All Suites Hotel

Yotau All Suites Hotel

3.5 out of 5
Av. San Martin No. 7, Santa Cruz
Stay at this 3.5-star family-friendly hotel in Santa Cruz. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Patio Design LifeStyle Center ...
6.8/10 (75 reviews)
"My issue was because the property inside the room was old needs a lot maintenance I found a underwear en the cabinet in the bathroom"

Reviewed on Aug 3, 2025

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Opens in a new windowYotau All Suites Hotel
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Hotel LP Santa Cruz Centro

Hotel LP Santa Cruz Centro

3 out of 5
Av.Ejercito Nacional 290, (frente Stadium Tahuichi), Santa Cruz
Stay at this 3-star business-friendly hotel in Santa Cruz. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Ramon Tahuichi Aguilera ...
7.8/10 Good! (280 reviews)
"Clean, friendly staff"

Reviewed on Jun 2, 2024

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Opens in a new windowHotel LP Santa Cruz Centro
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Our Top Santa Cruz Apartment Hotels

Apart Hotel Premium Suites Santa Cruz

Apart Hotel Premium Suites Santa Cruz

3.5 out of 5
Calle Las Begonias Nro 45, a 1 cuadra de la Av. San Martin, Santa Cruz
Stay at this 3.5-star business-friendly aparthotel in Santa Cruz. Enjoy free WiFi, free parking, and room service. Popular attractions Patio Design LifeStyle ...
8.6/10 Excellent! (91 reviews)
"Es buena locación , limpio , muy amables"

Reviewed on Sep 14, 2025

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Opens in a new windowApart Hotel Premium Suites Santa Cruz
Apartamento Irala

Apartamento Irala

3 out of 5
Calle Prolongancion Cochabamba, S/N, Edificios Altos del Sur, 1st Floor, Santa Cruz
Stay at this 3-star spa apartment in Santa Cruz. Enjoy free WiFi, free parking, and a full-service spa. Popular attractions Blacutt Square and Museo de Historia ...
"Good location. Building is new. Security is good. Condo unit is spacious for 2 people. Quiet environment. Responsive and reliable owner. Air-conditioning in bedroom only which is still acceptable."

Reviewed on Apr 16, 2019

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Opens in a new windowApartamento Irala
Buganvillas Hotel Suites & Spa

Buganvillas Hotel Suites & Spa

4 out of 5
Av. Roca y Coronado No. 901, Santa Cruz
Stay at this 4-star family-friendly hotel in Santa Cruz. Enjoy breakfast (surcharge), room service, and a fitness center. Popular attractions Parque Ecológico ...
7.4/10 Good! (93 reviews)
"Extremely satisfy with the service that this resort provided to us. Definitely will return back. Follow me on YouTube #TeamWithERVING"

Reviewed on Aug 14, 2021

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Opens in a new windowBuganvillas Hotel Suites & Spa
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Casa por Temporadas

Casa por Temporadas

3.5 out of 5
Avenida Cristo Redentor, frente al cementerio Las Misiones, Santa Cruz
Stay at this 3.5-star vacation home in Santa Cruz. Enjoy free WiFi, free parking, and an airport shuttle (surcharge). Popular attractions Play Land Amusement ...
Great place to stay, great attention
"The owners were happy to answer all our questions by email before our arrival. The pool was very nice but know that it has no shallow end. The pool table and air hockey table were nice additions, especially if it happens to rain while you are there. The owners know a great taxi driver if you don't ..."

Reviewed on Sep 21, 2016

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Opens in a new windowCasa por Temporadas
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Score Epic Santa Cruz Accommodation Deals

Marriott Santa Cruz de la Sierra Hotel

Marriott Santa Cruz de la Sierra Hotel

5 out of 5
4to Anillo Entre Radial 23, At Calle Las Ramblas, Santa Cruz, Santa Cruz
$103 nightly
The price is $103 total per night from Oct 18 to Oct 19
$103 total
Oct 18 - Oct 19
Stay at this 5-star luxury hotel in Santa Cruz. Enjoy free parking, a full-service spa, and a rooftop terrace. Our guests praise the helpful staff and the property ...
8.8/10 Excellent! (201 reviews)
"Very comfortable"

Reviewed on Sep 25, 2025

Opens in a new windowMarriott Santa Cruz de la Sierra Hotel
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

3.5 out of 5
Ave. San Martin, #455, Santa Cruz
$118 nightly
The price is $118 total per night from Oct 18 to Oct 19
$118 total
Oct 18 - Oct 19
Stay at this 3.5-star spa hotel in Santa Cruz. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular ...
8.8/10 Excellent! (331 reviews)
"Hotel was excellent. Staff excellent, check in good and bar resturant really good. room was good and clean"

Reviewed on Oct 3, 2025

Opens in a new windowLos Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
Ibis Santa Cruz DE LA Sierra

Ibis Santa Cruz DE LA Sierra

3 out of 5
AVENIDA CRISTOBAL DE MENDOZA, Santa Cruz
$43 nightly
The price is $43 total per night from Nov 11 to Nov 12
$43 total
Nov 11 - Nov 12
Stay at this 3-star business-friendly hotel in Santa Cruz. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our ...
9.4/10 Exceptional! (61 reviews)
"The"

Reviewed on Jul 28, 2025

Opens in a new windowIbis Santa Cruz DE LA Sierra
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TRYP by Wyndham Santa Cruz

TRYP by Wyndham Santa Cruz

4 out of 5
Av. San Martin, Calle 9 Este, no. 4, Equipetrol., Santa Cruz
$109 nightly
The price is $109 total per night from Oct 14 to Oct 15
$109 total
Oct 14 - Oct 15
Stay at this 4-star hotel in Santa Cruz. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...
9.2/10 Wonderful! (137 reviews)
"I suggest more fruits for breakfast , very limited options , king staff"

Reviewed on Aug 2, 2025

Opens in a new windowTRYP by Wyndham Santa Cruz
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Santa Cruz

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

3.5 out of 5
Ave. San Martin, #455, Santa Cruz
$118 nightly
The price is $118 total per night from Oct 18 to Oct 19
$118 total
Oct 18 - Oct 19
Stay at this 3.5-star spa hotel in Santa Cruz. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular ...
8.8/10 Excellent! (331 reviews)
"Hotel was excellent. Staff excellent, check in good and bar resturant really good. room was good and clean"

Reviewed on Oct 3, 2025

Opens in a new windowLos Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
Apart Hotel Premium Suites Santa Cruz

Apart Hotel Premium Suites Santa Cruz

3.5 out of 5
Calle Las Begonias Nro 45, a 1 cuadra de la Av. San Martin, Santa Cruz
Stay at this 3.5-star business-friendly aparthotel in Santa Cruz. Enjoy free WiFi, free parking, and room service. Popular attractions Patio Design LifeStyle ...
8.6/10 Excellent! (91 reviews)
"Es buena locación , limpio , muy amables"

Reviewed on Sep 14, 2025

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Opens in a new windowApart Hotel Premium Suites Santa Cruz
Buganvillas Hotel Suites & Spa
Great for families

Buganvillas Hotel Suites & Spa

4 out of 5
Av. Roca y Coronado No. 901, Santa Cruz
Stay at this 4-star family-friendly hotel in Santa Cruz. Enjoy breakfast (surcharge), room service, and a fitness center. Popular attractions Parque Ecológico ...
7.4/10 Good! (93 reviews)

Families like: Kids pool, cribs, rollaway beds, outdoor tennis courts

Travelers say...
"Extremely satisfy with the service that this resort provided to us. Definitely will return back. Follow me on YouTube #TeamWithERVING"

Reviewed on Aug 14, 2021

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Opens in a new windowBuganvillas Hotel Suites & Spa
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Camino Real Hotel
Great for families

Camino Real Hotel

4.5 out of 5
Av. San Martín y 4to. Anillo, Equipetrol Norte, Santa Cruz
$140 nightly
The price is $140 total per night from Oct 14 to Oct 15
$140 total
Oct 14 - Oct 15
Stay at this 4.5-star luxury hotel in Santa Cruz. Enjoy free breakfast, a full-service spa, and 2 bars/lounges. Popular attractions Ventura Mall and Santa Cruz ...
8.8/10 Excellent! (400 reviews)

Families like: Kids pool, waterslide, playground, babysitting

Travelers say...
"Very comfortable, great location. My favorite in Santa Cruz. Big enough / small enough"

Reviewed on Aug 25, 2025

Opens in a new windowCamino Real Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Need a Car For After Your Flight?

Economy

Chevrolet Spark or similar
  • 4 people
Chevrolet Spark
Economy Chevrolet Spark

Compact

Ford Focus or similar
  • 4 people
Ford Focus
Compact Ford Focus

Midsize

Toyota Corolla or similar
  • 5 people
Toyota Corolla
Midsize Toyota Corolla

SUV

Jeep Compass or similar
  • 5 people
Jeep Compass
SUV Jeep Compass

Santa Cruz

Orbitz provides convenient, one-stop shopping for travelers looking for budget flights to Santa Cruz or any other low fare domestic or international air travel.

Innovative Orbitz Tools for the Trip Planner on the Move

Now it is even faster to find exclusive deals and book cheap Santa Cruz flights from any location with our new Orbitz apps. These cutting-edge mobile tools are available free to anyone with an Android device, iPad, or iPhone. Look up Santa Cruz's most popular attractions, best restaurants, and entertainment venues or check on your flights to Santa Cruz and make changes to your itinerary while waiting in line for your latte.

Stay on Budget, Earn Miles with Bargain Santa Cruz Flights

You can find amazing discount fares with Orbitz’s guaranteed low prices or take advantage of last-minute sales and special travel packages. You can also earn points towards your airline frequent flyer programs when you book qualified flights to Santa Cruz. That means you can rack up money-saving points and miles for future use while saving money now.

We Are Just a Phone Call Away If You Need Us

Booking, changing, or canceling your Santa Cruz flights is a breeze with Orbitz’s online and mobile tools, but that doesn't mean that we leave you hanging if you want to speak with one of our representatives. If you need help, just contact our Customer Service by email or phone. To enjoy a less stressful trip, be sure to sign up for instant alerts so we can send you any updates or delays relating to your flights to Santa Cruz to your mobile phone or email.

Frequently asked questions

Which airlines fly to Santa Cruz?
Book a ticket with one of the 12 airlines that operate services to Viru Viru Intl. Airport (VVI) and gear up for awesome new adventures. This popular airport is a main gateway for exploring Santa Cruz. When it's time to check off this region, these trusted carriers will take you there:

  • BoA - 89 flights to Santa Cruz per month
  • Copa Airlines - 22 flights to Santa Cruz per month
  • Aerolineas Argentinas - 17 flights to Santa Cruz per month

How much is a flight to Santa Cruz?
Travelers from far and wide landed round-trip bargains ranging between $397 and $1,193 this week to Santa Cruz. Starting your trip from Fort Lauderdale (FLL)? The most affordable one-way prices were $193.
How to book the cheapest flight to Santa Cruz?
Scoring cheap flights to Santa Cruz is as simple as booking your ticket with Orbitz. But if you'd love to make sure you're walking away with the best flight deals around, here are some tips worth following:

  • Taking off from or landing at nearby airports can often help you save on airfares. Enter your preferred departure and arrival airports. Next, select the 'Nearby airports' function below to see what your options are.
  • Also, click on the 'Show flexible dates' option and you'll see the prices for days around your chosen departure. You may be able to pick up cheaper flight deals if your travel plans are flexible.
  • To filter your results, hit 'Show options.' You can search based on airlines, seating class, nonstop flights and refundable flights. You can also select your preferred flight times under 'Sort & Filter' to the left.
  • Reserve your fare as soon as you've decided on your travel dates. While you can get lucky on occasion, airline tickets rarely get more affordable as your date of departure gets closer.
  • Consider combining your flights, hotels and car rental into an Orbitz package to get more for your money.
  • If you can, avoid flying in high seasons. Airfares often surge during school breaks, summer and other vacation periods like Easter and Thanksgiving.

What is the best time to book a flight to Santa Cruz?
Generally speaking, January is the best time to book your plane ticket. This is closely followed by February and August. Keep this in mind while you browse for a cheap flight to Santa Cruz.
What day of the week is the cheapest to book a flight to Santa Cruz?
Typically, Tuesdays, Wednesdays and Saturdays are the cheapest days of the week to book a flight to Santa Cruz. If you want the most competitive airfares, search across those days and you just might land an excellent flight deal.
What is the cheapest day of the week to fly to Santa Cruz?
According to Orbitz data from 2020, you should kick off your trip on a Monday to nab cheap flights to Santa Cruz. Next most inexpensive day? Tuesday. Saturday costs the most. So, depart early in the week if you'd like to score a wallet-friendly fare without paying premium prices.
What is the cheapest month to fly to Santa Cruz?
We won't keep you in suspense — based on Orbitz data, August is generally the cheapest month to fly. Perfect for those who want a weekend getaway or simply escape from it all before the weather changes. The costliest time to fly is the height of summer, with fares at their highest in June.
Which airlines allow free cancellation?
Orbitz makes it a snap to find carriers that offer flexibility. Simply click on "Filter by flexible change policies" when searching for your Santa Cruz flights and boom! We'll show you options that include free cancellation within 24 hours of booking, no change fees and of course, an irresistible low price.
What do I need for the flight to Santa Cruz?
A lengthy flight can be daunting, but it's nothing a little preparation can't solve. We've compiled our top suggestions to ensure your journey is as smooth as possible:

  • In all cases you'll need some identification. How much? This depends on where you're traveling from. When reserving your flight tickets, we suggest to put down the same name, gender and birth date as displayed on your government-issued ID.
  • Take a good book or a laptop crammed with your favorite TV series — it'll help to keep you busy on your journey to Santa Cruz. Or if you'd rather enjoy a nap, a comfy eye mask will block out those bright cabin lights.
  • Long-haul trips can leave you feeling seriously cold, especially if you're flying overnight. If you don't want to curl up to the stranger beside you for warmth, bring your favorite hoodie and some wool socks.

How do I get cheap first-class/business deals to Santa Cruz?
If you think a first or business-class fare is out of your price range, you may want to think again. Here are some practical tips to help you score a premium flight to Santa Cruz for a whole lot less:

  • Be flexible with your travel dates and hold out for deals on business or first-class airfares.
  • Many budget airlines these days have superb business-class seating that doesn't cost an arm and a leg.
  • Take advantage of your airline's loyalty scheme and upgrade your seat. Alternatively, you can try bidding for an upgrade in online auctions.

What is the best time to go to Santa Cruz?
March, August and September are the most popular months to vacation in Santa Cruz. If an average daily high of 90 ºF sounds attractive, book your trip for the start of summer — December 1. Many tourists prefer this time of year for its warmer weather. In the evening, the average temperature falls to 70 ºF.
Travel tips for Santa Cruz

  • Santa Cruz is full of interesting attractions and Plaza 24 de Septiembre is one of them. Lock in a car rental and head there at your convenience.
  • Colinas del Urubo offers plenty of exciting experiences and is a great place to kick off your escape. Whether your scene is cafés, restaurants, art or something else, this city will keep you busy.

More to Explore

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.