$229 Cheap flights to Santa Cruz

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Top places to visit in Santa Cruz

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Santa Cruz

Santa Cruz

Cheap flights to Santa Cruz from $229 One Way, $469 Round Trip

$469 return flights and $229 one-way flights to Santa Cruz were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Wed, Jun 4 - Mon, Jun 9
MIA
Miami
VVI
Santa Cruz
$469 Roundtrip, found 7 hours ago
$469
Roundtrip
found 7 hours ago
Select Copa flight, departing Wed, Jun 4 from Miami to Santa Cruz, returning Mon, Jun 9, priced at $469 found 7 hours ago
Tue, Jun 3 - Wed, Jun 18
MIA
Miami
VVI
Santa Cruz
$506 Roundtrip, found 9 hours ago
$506
Roundtrip
found 9 hours ago
Select avianca flight, departing Tue, Jun 3 from Miami to Santa Cruz, returning Wed, Jun 18, priced at $506 found 9 hours ago
Tue, May 20 - Sun, May 25
IAD
Washington
VVI
Santa Cruz
$570 Roundtrip, found 1 day ago
$570
Roundtrip
found 1 day ago
Select United flight, departing Tue, May 20 from Washington to Santa Cruz, returning Sun, May 25, priced at $570 found 1 day ago
Wed, Nov 26 - Sun, Nov 30
MIA
Miami
VVI
Santa Cruz
$574 Roundtrip, found 8 hours ago
$574
Roundtrip
found 8 hours ago
Select Boliviana De Aviacion flight, departing Wed, Nov 26 from Miami to Santa Cruz, returning Sun, Nov 30, priced at $574 found 8 hours ago
Tue, Aug 12 - Fri, Aug 29
BWI
Baltimore
VVI
Santa Cruz
$580 Roundtrip, found 2 hours ago
$580
Roundtrip
found 2 hours ago
Select United flight, departing Tue, Aug 12 from Baltimore to Santa Cruz, returning Fri, Aug 29, priced at $580 found 2 hours ago
Tue, Aug 12 - Fri, Aug 29
DCA
Washington
VVI
Santa Cruz
$580 Roundtrip, found 2 hours ago
$580
Roundtrip
found 2 hours ago
Select United flight, departing Tue, Aug 12 from Washington to Santa Cruz, returning Fri, Aug 29, priced at $580 found 2 hours ago
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Deals For This Weekend's Flights

OriginDestinationTravel DatesFlights From*
MIASanta CruzMay 3 to May 11$590
IADSanta CruzMay 4 to May 14$754
IADSanta CruzMay 4 to May 14$754
LAXSanta CruzMay 4 to May 9$922
JFKSanta CruzMay 4 to May 11$975
*Prices include taxes and fees

Find The Perfect Hotel For After Your Flight

Score Epic Santa Cruz Accommodation Deals

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

3.5 out of 5
Ave. San Martin, #455, Santa Cruz
The price is $140 per night from May 29 to May 30
$140
$140 per night
May 29 - May 30
Stay at this 3.5-star spa hotel in Santa Cruz. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular ...
8.8/10 Excellent! (313 reviews)
"Amazing"

Reviewed on Mar 30, 2025

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
Hotel LP Equipetrol

Hotel LP Equipetrol

3.5 out of 5
Dr Victor Pinto, Equipetrol, esquina Marcelo Terceros Banzer, Santa Cruz
The price is $70 per night from May 13 to May 14
$70
$70 per night
May 13 - May 14
Stay at this 3.5-star hotel in Santa Cruz. Enjoy free WiFi, breakfast (surcharge), and room service. Popular attractions Ventura Mall and Santa Cruz Zoo are ...
"So, the mattress and pillows were not that comfortable, hard. No microwave and the sheets not the size of the bed, smaller. The treatment from the hotel personnel was good."

Reviewed on Feb 21, 2025

Hotel LP Equipetrol
Yotau All Suites Hotel

Yotau All Suites Hotel

3.5 out of 5
Av. San Martin No. 7, Santa Cruz
The price is $125 per night from May 2 to May 3
$125
$125 per night
May 2 - May 3
Stay at this 3.5-star family-friendly hotel in Santa Cruz. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Patio Design LifeStyle Center ...
6.8/10 (75 reviews)
"I like everything"

Reviewed on Apr 19, 2023

Yotau All Suites Hotel
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Hotel LP Santa Cruz Centro

Hotel LP Santa Cruz Centro

3 out of 5
Av.Ejercito Nacional 290, (frente Stadium Tahuichi), Santa Cruz
The price is $59 per night from May 13 to May 14
$59
$59 per night
May 13 - May 14
Stay at this 3-star business-friendly hotel in Santa Cruz. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions Ramon Tahuichi Aguilera ...
7.8/10 Good! (278 reviews)
"Clean, friendly staff"

Reviewed on Jun 2, 2024

Hotel LP Santa Cruz Centro
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Our Top Santa Cruz Apartment Hotels

Apart Hotel Premium Suites Santa Cruz

Apart Hotel Premium Suites Santa Cruz

3.5 out of 5
Calle Las Begonias Nro 45, a 1 cuadra de la Av. San Martin, Santa Cruz
The price is $30 per night from May 4 to May 5
$30
$30 per night
May 4 - May 5
Stay at this 3.5-star business-friendly aparthotel in Santa Cruz. Enjoy free WiFi, free parking, and room service. Popular attractions Patio Design LifeStyle ...
8.4/10 Very Good! (86 reviews)
"The state was mostly okay, but I didn't like the fact that they did not have anyone on site to receive me. When I got there. It took them about 10 minutes to arrive. And that was after I finally managed to get through to them on the phone."

Reviewed on Apr 18, 2025

Apart Hotel Premium Suites Santa Cruz
Apartamento Irala

Apartamento Irala

3 out of 5
Calle Prolongancion Cochabamba, S/N, Edificios Altos del Sur, 1st Floor, Santa Cruz
Stay at this 3-star spa apartment in Santa Cruz. Enjoy free WiFi, free parking, and a full-service spa. Popular attractions Blacutt Square and Cine Center are ...
8/10 Very Good! (1 review)
"Good location. Building is new. Security is good. Condo unit is spacious for 2 people. Quiet environment. Responsive and reliable owner. Air-conditioning in bedroom only which is still acceptable."

Reviewed on Apr 16, 2019

Get rates
Apartamento Irala
Buganvillas Hotel Suites & Spa

Buganvillas Hotel Suites & Spa

4 out of 5
Av. Roca y Coronado No. 901, Santa Cruz
The price is $60 per night from May 3 to May 4
$60
$60 per night
May 3 - May 4
Stay at this 4-star family-friendly hotel in Santa Cruz. Enjoy breakfast (surcharge), room service, and a fitness center. Popular attractions Parque Ecológico ...
"Extremely satisfy with the service that this resort provided to us. Definitely will return back. Follow me on YouTube #TeamWithERVING"

Reviewed on Aug 14, 2021

Buganvillas Hotel Suites & Spa
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Casa por Temporadas

Casa por Temporadas

3.5 out of 5
Avenida Cristo Redentor, frente al cementerio Las Misiones, Santa Cruz
Stay at this 3.5-star vacation home in Santa Cruz. Enjoy free WiFi, free parking, and an airport shuttle (surcharge). Popular attractions Play Land Amusement ...
10/10 Exceptional! (1 review)
Great place to stay, great attention
"The owners were happy to answer all our questions by email before our arrival. The pool was very nice but know that it has no shallow end. The pool table and air hockey table were nice additions, especially if it happens to rain while you are there. The owners know a great taxi driver if you don't ..."

Reviewed on Sep 21, 2016

Get rates
Casa por Temporadas
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Score Epic Santa Cruz Accommodation Deals

Marriott Santa Cruz de la Sierra Hotel

Marriott Santa Cruz de la Sierra Hotel

5 out of 5
4to Anillo Entre Radial 23, At Calle Las Ramblas, Santa Cruz, Santa Cruz
The price is $179 per night from May 15 to May 16
$179
$179 per night
May 15 - May 16
Stay at this 5-star luxury hotel in Santa Cruz. Enjoy free parking, a full-service spa, and a rooftop terrace. Our guests praise the helpful staff and the property ...
9/10 Wonderful! (187 reviews)
"Everything was amazing! Great staff and amazing service!"

Reviewed on Mar 25, 2025

Marriott Santa Cruz de la Sierra Hotel
Camino Real Hotel

Camino Real Hotel

4.5 out of 5
Av. San Martín y 4to. Anillo, Equipetrol Norte, Santa Cruz
The price is $113 per night from May 30 to May 31
$113
$113 per night
May 30 - May 31
Stay at this 4.5-star luxury hotel in Santa Cruz. Enjoy free breakfast, a full-service spa, and 2 bars/lounges. Popular attractions Ventura Mall and Santa Cruz ...
8.8/10 Excellent! (381 reviews)
"Superb Hotel. Lovely staff Pool area great. Close to everything in a good area."

Reviewed on Mar 14, 2025

Camino Real Hotel
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

3.5 out of 5
Ave. San Martin, #455, Santa Cruz
The price is $140 per night from May 29 to May 30
$140
$140 per night
May 29 - May 30
Stay at this 3.5-star spa hotel in Santa Cruz. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular ...
8.8/10 Excellent! (313 reviews)
"Amazing"

Reviewed on Mar 30, 2025

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
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Sun Hotel

Sun Hotel

3.5 out of 5
Av. Banzer Km 13, Aeropuerto Internacional Viru Viru, Santa Cruz, Santa Cruz
The price is $108 per night from May 2 to May 3
$108
$108 per night
May 2 - May 3
Stay at this 3.5-star business-friendly hotel in Santa Cruz. Enjoy free breakfast, free WiFi, and free parking. Popular attraction Play Land Amusement Park is ...
8.2/10 Very Good! (289 reviews)
"Great place"

Reviewed on Apr 13, 2025

Sun Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Santa Cruz

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

3.5 out of 5
Ave. San Martin, #455, Santa Cruz
The price is $140 per night from May 29 to May 30
$140
$140 per night
May 29 - May 30
Stay at this 3.5-star spa hotel in Santa Cruz. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular ...
8.8/10 Excellent! (313 reviews)
"Amazing"

Reviewed on Mar 30, 2025

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
Apart Hotel Premium Suites Santa Cruz

Apart Hotel Premium Suites Santa Cruz

3.5 out of 5
Calle Las Begonias Nro 45, a 1 cuadra de la Av. San Martin, Santa Cruz
The price is $30 per night from May 4 to May 5
$30
$30 per night
May 4 - May 5
Stay at this 3.5-star business-friendly aparthotel in Santa Cruz. Enjoy free WiFi, free parking, and room service. Popular attractions Patio Design LifeStyle ...
8.4/10 Very Good! (86 reviews)
"The state was mostly okay, but I didn't like the fact that they did not have anyone on site to receive me. When I got there. It took them about 10 minutes to arrive. And that was after I finally managed to get through to them on the phone."

Reviewed on Apr 18, 2025

Apart Hotel Premium Suites Santa Cruz
Buganvillas Hotel Suites & Spa
Great for families

Buganvillas Hotel Suites & Spa

4 out of 5
Av. Roca y Coronado No. 901, Santa Cruz
The price is $60 per night from May 3 to May 4
$60
$60 per night
May 3 - May 4
Stay at this 4-star family-friendly hotel in Santa Cruz. Enjoy breakfast (surcharge), room service, and a fitness center. Popular attractions Parque Ecológico ...

Families like: Kids pool, cribs, rollaway beds, outdoor tennis courts

Travelers say...
"Extremely satisfy with the service that this resort provided to us. Definitely will return back. Follow me on YouTube #TeamWithERVING"

Reviewed on Aug 14, 2021

Buganvillas Hotel Suites & Spa
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Camino Real Hotel
Great for families

Camino Real Hotel

4.5 out of 5
Av. San Martín y 4to. Anillo, Equipetrol Norte, Santa Cruz
The price is $113 per night from May 30 to May 31
$113
$113 per night
May 30 - May 31
Stay at this 4.5-star luxury hotel in Santa Cruz. Enjoy free breakfast, a full-service spa, and 2 bars/lounges. Popular attractions Ventura Mall and Santa Cruz ...
8.8/10 Excellent! (381 reviews)

Families like: Kids pool, waterslide, playground, babysitting

Travelers say...
"Superb Hotel. Lovely staff Pool area great. Close to everything in a good area."

Reviewed on Mar 14, 2025

Camino Real Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Need a Car For After Your Flight?

Economy

Chevrolet Spark or similar
  • 4 people
Miami, Missouri, USA
Chevrolet Spark
Economy Chevrolet Spark

Kompakt

Ford Focus or similar
  • 4 people
Miami, Missouri, USA
Ford Focus
Kompakt Ford Focus

Mittelklasse

Toyota Corolla or similar
  • 5 people
Miami, Missouri, USA
Toyota Corolla
Mittelklasse Toyota Corolla

SUV

Jeep Compass or similar
  • 5 people
Miami, Missouri, USA
Jeep Compass
SUV Jeep Compass

Santa Cruz

Get the absolute lowest prices on flights to Santa Cruz by shopping with Orbitz. Orbitz is the most efficient travel planner around, allowing you to search, compare and book discount domestic and international flights fast. With cutting-edge mobile tools and access to frequent flier rewards programs, we have everything you need for both your routine and holiday excursions.

Book Your Flight To Santa Cruz Using Your Mobile Device

New mobile app tools enable those with hand-held devices to scout out the best bargains and to secure tickets from any location. If you have an iPhone, iPad or Android device, you may take advantage of special discounts, only available to mobile device customers, when you book hotel rooms or car rentals on the same day as booking Santa Cruz flights.

Avoid Check-In Hassles When Traveling On Flights to Santa Cruz

Orbitz also provides an array of resources that can help you eliminate most check-in hassles. Detailed baggage information is continually available for Santa Cruz flights. Mobile apps can also be used to share travel itineraries with family members or business associates.

Keeping Everyone Up To Date

When you download the free Orbitz mobile phone app, you can get regular and free flight updates. These will keep you informed of important scheduling changes. Updates can even be sent to several contacts, helping to keep everyone current on anticipated arrival times and all other relevant flight details.

Orbitz makes traveling on a budget very easy to do. We provide everything you need to plan your ideal trip from start to finish. Getting there and back again is a snap when you book your Santa Cruz flight using Orbitz.

Frequently asked questions

Which airlines fly to Santa Cruz?
Book a ticket with one of the 12 airlines that operate services to Viru Viru Intl. Airport (VVI) and gear up for awesome new adventures. This popular airport is a main gateway for exploring Santa Cruz. When it’s time to check off this region, these trusted carriers will take you there:

  • BoA - 89 flights to Santa Cruz per month
  • Copa Airlines - 22 flights to Santa Cruz per month
  • Aerolineas Argentinas - 17 flights to Santa Cruz per month

How much is a flight to Santa Cruz?
Travelers from far and wide landed round-trip bargains ranging between $469 and $975 this week to Santa Cruz. Starting your trip from Miami (MIA)? The most affordable one-way prices were $229.
How to book the cheapest flight to Santa Cruz?
Scoring cheap flights to Santa Cruz is as simple as booking your ticket with Orbitz. But if you’d love to make sure you’re walking away with the best flight deals around, here are some tips worth following:

  • Taking off from or landing at nearby airports can often help you save on airfares. Enter your preferred departure and arrival airports. Next, select the ‘Nearby airports’ function below to see what your options are.
  • Also, click on the ‘Show flexible dates’ option and you’ll see the prices for days around your chosen departure. You may be able to pick up cheaper flight deals if your travel plans are flexible.
  • To filter your results, hit ‘Show options.’ You can search based on airlines, seating class, nonstop flights and refundable flights. You can also select your preferred flight times under ‘Sort & Filter’ to the left.
  • Reserve your fare as soon as you’ve decided on your travel dates. While you can get lucky on occasion, airline tickets rarely get more affordable as your date of departure gets closer.
  • Consider combining your flights, hotels and car rental into an Orbitz package to get more for your money.
  • If you can, avoid flying in high seasons. Airfares often surge during school breaks, summer and other vacation periods like Easter and Thanksgiving.

What is the best time to book a flight to Santa Cruz?
Generally speaking, January is the best time to book your plane ticket. This is closely followed by February and August. Keep this in mind while you browse for a cheap flight to Santa Cruz.
What day of the week is the cheapest to book a flight to Santa Cruz?
Typically, Tuesdays, Wednesdays and Saturdays are the cheapest days of the week to book a flight to Santa Cruz. If you want the most competitive airfares, search across those days and you just might land an excellent flight deal.
What is the cheapest day of the week to fly to Santa Cruz?
According to Orbitz data from 2020, you should kick off your trip on a Monday to nab cheap flights to Santa Cruz. Next most inexpensive day? Tuesday. Saturday costs the most. So, depart early in the week if you’d like to score a wallet-friendly fare without paying premium prices.
What is the cheapest month to fly to Santa Cruz?
We won’t keep you in suspense — based on Orbitz data, August is generally the cheapest month to fly. Perfect for those who want a weekend getaway or simply escape from it all before the weather changes. The costliest time to fly is the height of summer, with fares at their highest in June.
Which airlines allow free cancellation?
Orbitz makes it a snap to find carriers that offer flexibility. Simply click on “Filter by flexible change policies” when searching for your Santa Cruz flights and boom! We’ll show you options that include free cancellation within 24 hours of booking, no change fees and of course, an irresistible low price.
What do I need for the flight to Santa Cruz?
A lengthy flight can be daunting, but it’s nothing a little preparation can’t solve. We’ve compiled our top suggestions to ensure your journey is as smooth as possible:

  • In all cases you’ll need some identification. How much? This depends on where you’re traveling from. When reserving your flight tickets, we suggest to put down the same name, gender and birth date as displayed on your government-issued ID.
  • Take a good book or a laptop crammed with your favorite TV series — it’ll help to keep you busy on your journey to Santa Cruz. Or if you’d rather enjoy a nap, a comfy eye mask will block out those bright cabin lights.
  • Long-haul trips can leave you feeling seriously cold, especially if you’re flying overnight. If you don’t want to curl up to the stranger beside you for warmth, bring your favorite hoodie and some wool socks.

How do I get cheap first-class/business deals to Santa Cruz?
If you think a first or business-class fare is out of your price range, you may want to think again. Here are some practical tips to help you score a premium flight to Santa Cruz for a whole lot less:

  • Be flexible with your travel dates and hold out for deals on business or first-class airfares.
  • Many budget airlines these days have superb business-class seating that doesn’t cost an arm and a leg.
  • Take advantage of your airline’s loyalty scheme and upgrade your seat. Alternatively, you can try bidding for an upgrade in online auctions.

What is the best time to go to Santa Cruz?
March, August and September are the most popular months to vacation in Santa Cruz. If an average daily high of 90 ºF sounds attractive, book your trip for the start of summer — December 1. Many tourists prefer this time of year for its warmer weather. In the evening, the average temperature falls to 70 ºF.
Travel tips for Santa Cruz

  • Santa Cruz is full of interesting attractions and Plaza 24 de Septiembre is one of them. Lock in a car rental and head there at your convenience.
  • Colinas del Urubo offers plenty of exciting experiences and is a great place to kick off your escape. Whether your scene is cafés, restaurants, art or something else, this city will keep you busy.

City Destinations in Santa Cruz

More Popular Airlines

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.