Spa Resorts in Central Missouri, MO
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Featured Central Missouri Spa Resorts & Hotels

Lodge Of Four Seasons Golf Resort, Marina & Spa
315 Four Seasons Dr. Lake Ozark MO
Free Cancellation
Reserve now, pay when you stay
$100 nightly
The price is $109 total per night
$109 total
Jan 12 - Jan 13, 2026
Total with taxes and fees
Lodge Of Four Seasons Golf Resort, Marina & Spa features a golf course, a marina, and a full-service spa. The 24-hour front desk has staff standing by to help with luggage storage, and answer any questions about the accommodations. Other amenities at this beach resort include an indoor pool, a gym, and a sauna.
Pool
Hot Tub

The Lodge at Old Kinderhook Golf Resort
678 Old Kinderhook Drive Camdenton MO
Free Cancellation
Reserve now, pay when you stay
$146 nightly
The price is $154 total per night
$154 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
The Lodge at Old Kinderhook Golf Resort features a golf course, a marina, and a full-service spa. The front desk is staffed 24/7 to help with concierge services, luggage storage, and dry cleaning/laundry. Other amenities at this beach hotel include an indoor pool, an outdoor pool, and a gym.
Pool
Spa

Hotel Bothwell Sedalia Central District, an Ascend Collection Hotel
103 E 4th St Sedalia MO
Free Cancellation
$110 nightly
The price is $125 total per night
$125 total
Jan 28 - Jan 29, 2026
Total with taxes and fees
Guests of Hotel Bothwell Sedalia Central District, an Ascend Collection Hotel enjoy a gym, free WiFi in public areas, and conference space. If you plan to drive, free parking is available. The 24-hour front desk has staff standing by to help with luggage storage and securing valuables. Additional amenities include a business center, a microwave in a common area, and laundry facilities.
Breakfast included
Pet friendly

Parkfield Inn
506 Kansas Ave Clinton MO
Free Cancellation
Reserve now, pay when you stay
$107 nightly
The price is $121 total per night
$121 total
Dec 29 - Dec 30
Total with taxes and fees
At Parkfield Inn, guests have access to an indoor pool, free WiFi in public areas, and a hot tub. If you drive, put free parking to good use. The 24-hour front desk has staff always at the ready. Additional amenities include conference space, laundry facilities, and a banquet hall.
Pool
Hot Tub

Camden on the Lake Resort & Spa
2359 Bittersweet Road Lake Ozark MO
$136 nightly
The price is $145 total per night
$145 total
Dec 29 - Dec 30
Total with taxes and fees
Guests of Camden on the Lake Resort & Spa have access to a marina, a full-service spa, and a gym. If you drive, take advantage of free parking. Front-desk staff can answer questions 24/7, and assist with luggage storage, concierge services, and securing valuables. Other amenities at this spa resort include 2 hot tubs, free WiFi in public areas, and meeting rooms.
Pool
Hot Tub

Wingate by Wyndham - Columbia
3101 Wingate Ct Columbia MO
Free Cancellation
Reserve now, pay when you stay
$81 nightly
The price is $92 total per night
$92 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
Guests of Wingate by Wyndham - Columbia enjoy a 24-hour gym, free WiFi in public areas, and a conference center. You can take advantage of free parking if you drive. Multilingual staff at the front desk are standing by 24/7 to help with dry cleaning/laundry, luggage storage, and securing valuables. Additional amenities include coffee/tea in a common area, a computer station, and express check-out.
Breakfast included
Parking included

Stoney Creek Hotel Columbia
2601 S Providence Rd Columbia MO
Free Cancellation
Reserve now, pay when you stay
$110 nightly
The price is $124 total per night
$124 total
Dec 29 - Dec 30
Total with taxes and fees
Stoney Creek Hotel Columbia features an indoor pool, an outdoor pool, and a gym. You can take advantage of free parking if you drive. The front desk is staffed 24 hours a day to help with dry cleaning/laundry and luggage storage. Additional amenities include free WiFi in public areas, a hot tub, and meeting rooms.
Pool
Hot Tub

Holiday Inn Express Hotel & Suites Rolla - U of Missouri S&T by IHG
1610 Old Wire Outer Rd Rolla MO
Free Cancellation
$137 nightly
The price is $154 total per night
$154 total
Jan 18 - Jan 19, 2026
Total with taxes and fees
At Holiday Inn Express Hotel & Suites Rolla - U of Missouri S&T by IHG, guests enjoy an indoor pool, a gym, and free WiFi in public areas. If you decide to drive, there's free parking. Front-desk staff can help with dry cleaning or laundry, and provide local restaurant recommendations. Additional amenities include a hot tub, conference space, and a 24-hour business center.
Pool
Hot Tub

Parkfield Inn
151 N Dam Access Road Warsaw MO
Free Cancellation
Reserve now, pay when you stay
$107 nightly
The price is $120 total per night
$120 total
Dec 29 - Dec 30
Total with taxes and fees
Parkfield Inn offers an indoor pool, free WiFi in public areas, and a hot tub. Free parking is included with your stay. The 24-hour front desk has staff always at the ready. Additional amenities include a meeting room, laundry facilities, and a banquet hall.
Pool
Hot Tub

Country Inn & Suites by Radisson, Columbia, MO
817 N Keene St Columbia MO
Free Cancellation
$78 nightly
The price is $88 total per night
$88 total
Jan 18 - Jan 19, 2026
Total with taxes and fees
At Country Inn & Suites by Radisson, Columbia, MO, guests enjoy an indoor pool, a gym, and free WiFi in public areas. A stay here includes free parking. Front-desk staff can answer questions 24/7, and assist with dry cleaning/laundry, luggage storage, and securing valuables. Additional amenities include a hot tub, conference space, and a business center.
Pool
Hot Tub

Americas Best Value Inn St. Robert
110 Carmel Valley Way St. Robert MO
Free Cancellation
Reserve now, pay when you stay
$76 nightly
The price is $85 total per night
$85 total
Jan 1 - Jan 2, 2026
Total with taxes and fees
Guests of Americas Best Value Inn St. Robert enjoy free WiFi in public areas, a business center, and a computer station. If you plan to drive, free parking is available. The 24-hour front desk has staff standing by to help secure valuables, and answer any questions about the accommodations. Additional amenities include laundry facilities and a vending machine.
Breakfast included
Pet friendly

Margaritaville Lake Resort Lake of the Ozarks
494 Tan Tar A Drive Osage Beach MO
Free Cancellation
Reserve now, pay when you stay
$133 nightly
The price is $142 total per night
$142 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
Margaritaville Lake Resort Lake of the Ozarks features a golf course, a marina, and a full-service spa. If you plan to drive, free parking is available. Front-desk staff can answer questions 24/7, and assist with concierge services, securing valuables, and luggage storage. Other amenities at this spa resort include 3 outdoor pools, an indoor pool, and a children's pool.
Pool
Spa

Inn at Grand Glaize
5142 Osage Beach Pkwy Osage Beach MO
Free Cancellation
Reserve now, pay when you stay
$57 nightly
The price is $62 total per night
$62 total
Jan 19 - Jan 20, 2026
Total with taxes and fees
Guests of Inn at Grand Glaize have access to a marina, a casino, and karaoke. If you decide to drive, there's free parking. The front desk has multilingual staff standing by 24 hours a day to assist with securing valuables and concierge services. If you like to take your furry friend along on your adventures, this pet-friendly property offers an off-leash area. Other amenities at this golf hotel include a 24-hour gym, a sauna, and free WiFi in public areas.
Pool
Hot Tub

Baymont by Wyndham Rolla
1801 Martin Springs Dr Rolla MO
Free Cancellation
Reserve now, pay when you stay
$80 nightly
The price is $90 total per night
$90 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
Guests of Baymont by Wyndham Rolla enjoy a gym, free WiFi in public areas, and a business center. If you decide to drive, there's free parking. The front desk is staffed 24/7 to help with luggage storage, and answer any questions about the accommodations. Additional amenities include coffee/tea in a common area, a computer station, and express check-out.
Breakfast included
Pet friendly

Super 8 by Wyndham Lake of the Ozarks
10 Midway Rd Eldon MO
Free Cancellation
Reserve now, pay when you stay
$65 nightly
The price is $69 total per night
$69 total
Jan 3 - Jan 4, 2026
Total with taxes and fees
Guests of Super 8 by Wyndham Lake of the Ozarks enjoy access to free WiFi in public areas, a conference center, and a business center. If you decide to drive, there's free parking. The 24-hour front desk has multilingual staff ready to assist with sightseeing, directions, and local dining recommendations. Additional amenities include coffee/tea in a common area, a computer station, and express check-out.
Breakfast included
Pet friendly
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See all available properties in Central Missouri
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Central Missouri hotels essential information
Accommodation | 4,773 hotels |
|---|---|
Lowest Price | $62 |
Highest Price | $154 |
Popular hotels | Lodge Of Four Seasons Golf Resort, Marina & Spa, The Lodge at Old Kinderhook Golf Resort, Hotel Bothwell Sedalia Central District, an Ascend Collection Hotel, Parkfield Inn, Camden on the Lake Resort & Spa, Wingate by Wyndham - Columbia, Stoney Creek Hotel Columbia, Holiday Inn Express Hotel & Suites Rolla - U of Missouri S&T by IHG, Parkfield Inn, Country Inn & Suites by Radisson, Columbia, MO, Americas Best Value Inn St. Robert, Margaritaville Lake Resort Lake of the Ozarks, Inn at Grand Glaize, Baymont by Wyndham Rolla, Super 8 by Wyndham Lake of the Ozarks |
Recent Spa Resorts & Hotels Reviews

Drury Plaza Hotel Columbia East
5/5 Excellent
"The desk attendant was very helpful when we needed a room change due to a toilet that was not working. She even provided us a room upgrade! Another employee let us know that we could watch the football game that was on Prime on the lounge TV on a channel in our room. We are grateful for that. Meals and drinks are very nice."
A verified traveler stayed at Drury Plaza Hotel Columbia East
Posted 2 days ago
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