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Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG

2.5 star property
Hotel with free breakfast, steps from Market Arcade Building

Choose dates to view prices

Photo gallery for Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG

1 bedroom, in-room safe, desk, laptop workspace
Lobby sitting area
Free daily buffet breakfast
Lobby sitting area
Business center

Reviews

8.6 out of 10
Excellent

Popular amenities

  • Free WiFi
  • Air conditioning
  • Gym
  • Business services
  • Laundry

Explore the area

View in a map
601 Main St, Buffalo, NY, 14203
  • Place, Shea's Performing Arts Center
    ‪2 min walk‬
  • Place, Buffalo Niagara Convention Center
    ‪5 min walk‬
  • Place, Niagara Square
    ‪6 min walk‬
  • Airport, Buffalo, NY (BUF-Buffalo Niagara Intl.)
    ‪13 min drive‬

Room options

View all photos for Standard Room

Standard Room | 1 bedroom, in-room safe, desk, laptop workspace

Standard Room

9.2 out of 10
Wonderful
(25 reviews)
  • 500 sq ft
  • Sleeps 2
  • 1 King Bed and 1 Double Sofa Bed

View all photos for Suite, 1 Bedroom

Suite, 1 Bedroom | 1 bedroom, in-room safe, desk, laptop workspace

Suite, 1 Bedroom

9.0 out of 10
Wonderful
(44 reviews)
  • 500 sq ft
  • 1 bedroom
  • City view
  • Sleeps 4
  • 1 King Bed

View all photos for Suite, 1 Bedroom, Accessible (Mobility Accessible, Bathtub)

Combined shower/tub, eco-friendly toiletries, hair dryer, towels

Suite, 1 Bedroom, Accessible (Mobility Accessible, Bathtub)

9.6 out of 10
Exceptional
(4 reviews)
  • 500 sq ft
  • Sleeps 4
  • 1 Queen Bed

View all photos for Suite, 1 Bedroom, Accessible (Mobility Accessible, Roll-in Shower)

Combined shower/tub, eco-friendly toiletries, hair dryer, towels

Suite, 1 Bedroom, Accessible (Mobility Accessible, Roll-in Shower)

9.0 out of 10
Wonderful
(4 reviews)
  • 500 sq ft
  • Sleeps 4
  • 1 Queen Bed

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About the neighborhood

Buffalo

Located in Downtown Buffalo, Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG is next to popular attractions like Market Arcade Building and Buffalo Music Hall of Fame. This 146-room hotel welcomes guests with free breakfast and conveniences like free in-room WiFi and a gym.

What's nearby

  • Chippewa District - 1 min walk - 0.0 miles
  • Shea's Performing Arts Center - 2 min walk - 0.1 miles
  • Fountain Plaza - 2 min walk - 0.1 miles
  • Buffalo Niagara Convention Center - 5 min walk - 0.3 miles
  • Niagara Square - 6 min walk - 0.4 miles

Getting around

  • Fountain Plaza Station - 1 min walk
  • Buffalo-Exchange Street Station - 18 min walk
  • Buffalo Niagara Intl. Airport (BUF) - 21 min drive

Restaurants

  • ‪Bada Bing - ‬2 min walk
  • ‪The House Of Charm - ‬4 min walk
  • ‪Streetlight Brasserie - ‬3 min walk
  • ‪Soho Burger Bar - ‬3 min walk
  • ‪Eddie Brady's - ‬3 min walk

About this property

Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG

Hotel with free breakfast, steps from Market Arcade Building
Guests of Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG enjoy a gym, free WiFi in public areas, and a business center. Front-desk staff can answer questions 24/7, and assist with securing valuables, luggage storage, and dry cleaning/laundry. Additional amenities include express check-out, laundry facilities, and a vending machine.
Guests can expect free WiFi and 49-inch TVs with cable channels. Bathrooms have hair dryers and free toiletries. Other amenities include sofa beds, sitting areas, and refrigerators.
Recreational amenities at the hotel include a fitness center.

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  • Free WiFi
  • Restaurant
  • Air conditioning
9.0 out of 10, Wonderful, 1,741 reviews
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Jan 26 - Jan 27
Total with taxes and fees
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Property amenities

Internet

  • Available in all rooms: Free WiFi
  • Available in some public areas: Free WiFi

Parking and transportation

  • Offsite parking available (USD 16 per day)
  • Wheelchair-accessible parking and van parking available
  • Onsite parking options include a garage

Food and drink

  • Free buffet breakfast available daily 6:00 AM to 10:00 AM

Things to do

  • Gym

Family friendly

  • In-room crib
  • In-room microwave
  • In-room refrigerator
  • In-room sofa bed
  • Laundry facilities
  • Living room
  • Separate bedroom

Conveniences

  • 24-hour front desk
  • Guidebooks
  • Laundry facilities
  • Luggage storage
  • Safe at front desk
  • Vending machine

Guest services

  • Dry cleaning/laundry service
  • Housekeeping (daily)

Business services

  • Business center

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Assistive listening devices
  • Elevator
  • Grab bar in shower
  • Grab bar near toilet
  • Hand-held showerhead
  • Handrails in stairways
  • Height-adjustable showerhead
  • In-room roll-in shower
  • Lever door handles
  • Low-height electrical outlets in bathroom
  • Portable shower seat
  • Raised toilet seat
  • Visual fire alarm
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible bathroom vanity
  • Wheelchair-accessible business center
  • Wheelchair-accessible gym
  • Wheelchair-accessible parking
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible path to elevator
  • Wheelchair-accessible public washroom
  • Wheelchair-accessible registration desk
  • Wheelchair-accessible restaurant
  • Wheelchair-accessible van parking

More

  • 7 floors
  • At least 80% lighting from LEDs
  • Comprehensive food waste policy
  • Eco-friendly cleaning products used
  • Smoking not allowed
  • Vegetarian breakfast available
  • Vegetarian dining options

Room amenities

Bedroom

  • Bedsheets provided
  • Blackout drapes
  • Double sofa bed
  • Free crib

Bathroom

  • Free toiletries
  • Hair dryer
  • Private bathroom
  • Shower/bathtub combination
  • Towels provided

Entertainment

  • 49-inch TV with cable channels

Food and drink

  • Coffee/tea maker
  • Microwave
  • Refrigerator
  • Restaurant dining guides

More

  • Air conditioning (climate-controlled)
  • Bulk dispensers for toiletries
  • Connecting rooms available
  • Desk
  • Eco-friendly toiletries
  • Free local calls
  • Heating
  • Iron/ironing board
  • Laptop workspace
  • LED lighting
  • Living room
  • Phone
  • Safe
  • Separate sitting area

Policies

Check-in

Check-in start time: 3:00 PM; Check-in end time: anytime
Contactless check-in available
Minimum check-in age: 21

Check-out

Check-out before 11 AM
Contactless check-out available
Express check-out available

Special check-in instructions

Front desk staff will greet guests on arrival at the property
Information provided by the property may be translated using automated translation tools

Access methods

Staffed front desk

Pets

  • Service animals exempt from fees

Children and extra beds

  • Children 18 years old and younger stay free when using existing bedding
  • Free cribs/infant beds are available

Property payment types

Important information

Optional extras

These fees and deposits will be charged at check-in, check-out, or the time of service.

  • Nearby parking fee: USD 16.00 per day (500 ft away)

This list may not be comprehensive. Fees and deposits might not include tax and are subject to change.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
The name on the credit card used at check-in to pay for incidentals must be the primary name on the guestroom reservation
This property accepts credit cards; cash is not accepted
This property uses eco-friendly cleaning products
Safety features at this property include a smoke detector and window guards
This property affirms that it follows the cleaning and disinfection practices of Clean Promise (IHG)
Please note that cultural norms and guest policies may differ by country and by property; the policies listed are provided by the property
  • Check-in: 3:00 PM
  • Check-out: 11 AM
  • Minimum check-in age: 21
The front desk is open 24 hours a day, and checking out is easy with express services.

We should mention

Details about charges, deposits, or other important information:

  • This property is managed by a professional host. The provision of housing is linked to their trade, business, or profession.
  • Charges for extra guests may apply and vary depending on the property's policy.
  • A cash deposit, credit card, or debit card for incidental charges, as well as a government-issued photo ID, may be required at check-in.
  • Special requests are subject to availability at the time of check-in and can't be guaranteed. Certain requests may come with additional charges.
  • This property accepts credit cards. Cash is not accepted. 
  • The credit card used at check-in for incidentals must be in the name of the primary guest who made the reservation.
  • This property uses eco-friendly cleaning products.
  • Onsite safety features include a smoke detector and window guards.
  • This property affirms that it follows the cleaning and disinfection practices of Clean Promise (IHG).

Additional information about polices, regulations, and more:

  • Registered guests are the only ones allowed in guestrooms.
  • Connecting or adjoining rooms can be requested, but all rooms are subject to availability. Contact the property using the phone number on your booking confirmation.
  • No rollaway or extra beds are available.
  • This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly).

Property is also known as

Holiday Inn Express Buffalo Downtown Hotel
Comfort Suites Hotel Downtown
Comfort Suites Downtown Hotel Buffalo
Comfort Suites Downtown Buffalo
Comfort Suites Downtown Buffalo Hotel
Comfort Suites Buffalo
Buffalo Comfort Suites
Holiday Inn Express Buffalo Downtown
Holiday Inn Express Suites Buffalo Downtown
Holiday Inn Express Suites Buffalo Downtown Medical CTR
Holiday Inn Express Suites Buffalo Downtown Medical CTR by IHG

Frequently asked questions

Is free cancellation available at Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG?

Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG offers free cancellation on select room rates. For additional details, take a look at the cancellation policy on Orbitz.

How much does it cost to stay at Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG?

As of Jan 19, 2026, prices found for a 1-night stay for 2 adults at Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG on Feb 2, 2026 start from $112.0, excluding taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.

What is there to do close to Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG?

This hotel is situated in Downtown Buffalo, just steps from Shea's Performing Arts Center and Buffalo Music Hall of Fame, and within a short walk of Niagara Square. You'll also find KeyBank Center and Lake Erie within a short drive.

Will I be able to park at Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG?

Yes, there is accessible parking available.

Does Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG include a casino at the property?

No, Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG doesn't have a casino.

Is there an indoor pool at Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG?

No, there is no indoor pool at this hotel.

What do couples enjoy most about Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG?

Couples staying at this hotel will appreciate amenities like free breakfast and a 24-hour front desk plus some guestrooms include city views.

Are there hot tubs at Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG?

No, this hotel doesn't have a spa tub.

Does Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG have a restaurant that serves breakfast?

Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG offers free buffet breakfast each morning though there is no restaurant.

Does Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG allow pets to stay for free?

No, pets aren't allowed at Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG though service animals are welcome.

Does Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG have connecting rooms?

Yes, you can book connecting guestrooms at this hotel for your group or family vacation.

Where is the closest airport to Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG?

The closest major airport to Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG is Buffalo Niagara Intl. Airport (BUF), which is 10.3 mi away (21 minutes by car). Another top airport is Niagara Falls, NY (IAG-Niagara Falls Intl.), which is located 22 mi away (30-minute drive).

Can I book a room with a balcony at Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG?

No, there aren't any guestrooms with balconies at Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG.

Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG Reviews

Reviews

8.6

Excellent

Rating 10 - Excellent. 560 out of 1002 reviews
Rating 8 - Good. 288 out of 1002 reviews
Rating 6 - Okay. 72 out of 1002 reviews
Rating 4 - Poor. 37 out of 1002 reviews
Rating 2 - Terrible. 45 out of 1002 reviews

9.0/10

Cleanliness

8.8/10

Staff & service

8.2/10

Amenities

8.6/10

Property conditions & facilities

Reviews

6/10 Okay

Donn

Stayed 1 night in Oct 2025

2/10 Terrible

Marco

Stayed 2 nights in Oct 2025

6/10 Okay

Amber

Disliked: Staff & service

Great Stay with the Exception of 1 Front Desk girl

Overall, our stay was good — the hotel itself was clean, comfortable, and well-kept. The breakfast was great, and every staff member we interacted with during our four-day stay was friendly and professional… except for the experience when we first arrived. We got to the hotel about an hour before check-in because we were heading to a football game. The woman behind the front desk told us we’d have to wait the hour, which I understood, but when I asked to use the bathroom to get changed, her attitude was rude and dismissive. She spoke under her breath about me, and when I asked what she said, she got defensive and told me she “wasn’t talking to me.” She also told me they “don’t check bags,” but I could “just leave them there,” which didn’t feel secure or professional. She wasn’t in uniform or wearing a name tag and seemed more like she was hanging out than working. Thankfully, we never saw her again, and everyone else at the hotel was wonderful. Still, that first encounter really set a bad tone for the start of our trip.
Stayed 3 nights in Oct 2025

4/10 Poor

Diana

Business traveler
Nice rooms Did not have breakfast
Stayed 2 nights in Sep 2025

10/10 Excellent

Nicholas

Traveled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Clean and comfortable
Stayed 1 night in Oct 2025

10/10 Excellent

Mia

Stayed 1 night in Oct 2025

10/10 Excellent

Merry

Traveled with partner, Traveled with family
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The staff made our stay an excellent experience. They were fantastic. The room was very large and comfortable. All in all, a very good experience.
Stayed 2 nights in Oct 2025

10/10 Excellent

Daniel

Liked: Cleanliness, staff & service, property conditions & facilities
Clean, nice staff, good breakfast
Stayed 3 nights in Oct 2025

10/10 Excellent

John

Stayed 2 nights in Oct 2025

10/10 Excellent

Matthew

Stayed 2 nights in Oct 2025

8/10 Good

laura

Traveled with family
Liked: Cleanliness, staff & service, room comfort

Good Location and hearty breakfast included

Very good location, staff was friendly and helpful and a pretty substantial breakfast offering which remained decently stocked even nearing the end of service time. Room was large and comfortable. Hotel itself seems a bit aged , but suited all of our needs for a family gathering and was appropriate for the price we paid.
Stayed 3 nights in Oct 2025

8/10 Good

Phillip

Stayed 2 nights in Sep 2025

10/10 Excellent

Kimberly

Business traveler
Liked: Cleanliness, staff & service, property conditions & facilities
Night staff was super friendly and welcoming! Rooms are spacious and comfortable
Stayed 1 night in Oct 2025

2/10 Terrible

Jessica

Traveled with family
Disliked: Cleanliness, staff & service, amenities, property conditions & facilities
Hotel canceled our reservations at 6 pm the night of which left us with no downtown options in Buffalo. They were overbooked. They moved 14 guests to a location outside of downtown which moved all of our plans. Hotel office blamed us for not getting there at 3 pm to confirm room. We had our bags in their office at 1 pm. It was the craziest experience. Hotel didn’t seem to be in great condition and would never trust myself to stay there again knowing what they did to multiple guest who all felt stranded and confused how they would let this happened sold out or not.
Stayed 2 nights in Sep 2025

8/10 Good

Matthew

Liked: Cleanliness, staff & service, amenities
A good central location to get around town and close to the RallyBus pickup point for Bills games. Very close to metro station to travel (free) down to KeyBank Arena for Sabres games. Complimentary breakfast is fine for what it is. There is a good coffee place (over winter coffee) around the block for those who are after a real coffee. Staff are friendly and rooms very clean with daily service. Rooms are a good size with separate bedroom. If traveling as family with kids, would consider Niagara Falls as a more suitable location vs. Downtown if you are only visiting for Bills game.
Stayed 3 nights in Sep 2025

6/10 Okay

Eugenio

Liked: Cleanliness, room comfort
Stayed 1 night in Sep 2025

10/10 Excellent

JAMES

Traveled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Big suite comfy & well designed. Close in. Easy access to Theater District and all down Main to Canalside. Hreat comvention-going spoi. Plemty of room to store bikes in room. Good breakfast, same offerings every day
Stayed 5 nights in Sep 2025

4/10 Poor

Taylor

Stayed 1 night in Sep 2025

10/10 Excellent

Daryl

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Very simple yet comfortable rooms
Stayed 2 nights in Sep 2025

6/10 Okay

Matthew

Liked: Cleanliness, staff & service, amenities
Disliked: Property conditions & facilities
Clean, staff are nice and friendly. But the property itself is getting a little old and room had a very noisy rattle aircon that was kind of broken. Made it hard to sleep. The complimentary breakfast is good with enough options to start the day.
Stayed 3 nights in Sep 2025

10/10 Excellent

Raja

Traveled with family
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Aug 2025

2/10 Terrible

Tracey

They oversold Our room and we had to move
Stayed 1 night in Sep 2025

10/10 Excellent

LINDA

Traveled with group
Liked: Cleanliness, staff & service, amenities
Clean, large room. Nice bed
Stayed 1 night in Sep 2025

10/10 Excellent

Steven

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Great place to stay in Buffalo

It was a large room, with a nice king size bed. I liked that it had a fridge and microwave. I also liked the location in the theater district, very convenient.
Stayed 2 nights in Sep 2025

8/10 Good

Carl

Liked: Cleanliness, staff & service, property conditions & facilities
Stayed 3 nights in Sep 2025