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Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG

Property class: 2.5

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Photo gallery for Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG

A hotel room with a bed, a TV, a desk, a chair, and a sofa.
A modern hotel lobby with seating areas, large windows, and a view of the outdoors.
A buffet with labeled containers of omelets and other dishes.
A reception desk with a computer, printer, and a vase of flowers.
A modern hotel lobby with green sofas, grey armchairs, and a central table with a vase.

Reviews

8.6 out of 10
Excellent

Popular amenities

  • Free WiFi
  • Air conditioning
  • Gym
  • Business services
  • Laundry

Explore the area

View in a map
601 Main St, Buffalo, NY, 14203
  • Place, Shea's Performing Arts Center
    ‪2 min walk‬
  • Place, Buffalo Convention Center
    ‪6 min walk‬
  • Place, Niagara Square
    ‪8 min walk‬
  • Airport, Buffalo, NY (BUF-Buffalo Niagara Intl.)
    ‪22 min drive‬

Room options

View all photos for Standard Room

A bed with white bedding and a wooden headboard.

Standard Room

9.2 out of 10
Wonderful
(30 reviews)
  • 500 sq ft
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed and 1 Double Sofa Bed
  • Free WiFi

View all photos for Suite, 1 Bedroom

1 bedroom, in-room safe, desk, laptop workspace

Suite, 1 Bedroom

8.8 out of 10
Excellent
(69 reviews)
  • City view
  • 500 sq ft
  • 1 bedroom
  • Sleeps 4
  • 1 King Bed
  • Free WiFi

View all photos for Suite, 1 Bedroom, Accessible (Mobility Accessible, Bathtub)

A bathroom with a shower, toilet, and sink.

Suite, 1 Bedroom, Accessible (Mobility Accessible, Bathtub)

9.6 out of 10
Exceptional
(4 reviews)
  • 500 sq ft
  • 1 bedroom
  • Sleeps 4
  • 1 Queen Bed
  • Free WiFi

View all photos for Suite, 1 Bedroom, Accessible (Mobility Accessible, Roll-in Shower)

A bathroom with a shower, toilet, and sink.

Suite, 1 Bedroom, Accessible (Mobility Accessible, Roll-in Shower)

9.0 out of 10
Wonderful
(4 reviews)
  • 500 sq ft
  • 1 bedroom
  • Sleeps 4
  • 1 Queen Bed
  • Free WiFi

DOUBLE Accessible-Queen Size Bed

  • Sleeps 4
  • Free WiFi

DOUBLE KING SIZE BED

  • Sleeps 4
  • Free WiFi

Room TWO BEDS

  • Sleeps 10
  • Free WiFi

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About the neighborhood

Buffalo

Located in Downtown Buffalo, Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG is next to popular attractions like Market Arcade Building and Buffalo Music Hall of Fame. This 146-room hotel welcomes guests with free breakfast and conveniences like free in-room WiFi and a gym.

What's nearby

  • Chippewa District - 1 min walk - 0.0 miles
  • Shea's Performing Arts Center - 2 min walk - 0.1 miles
  • Fountain Plaza - 2 min walk - 0.1 miles
  • Buffalo Convention Center - 6 min walk - 0.4 miles
  • Niagara Square - 8 min walk - 0.5 miles

Getting around

  • Fountain Plaza Station - 1 min walk
  • Buffalo-Exchange Street Station - 18 min walk
  • Buffalo Niagara Intl. Airport (BUF) - 21 min drive

Restaurants

  • ‪McDonald's - ‬17 min walk
  • ‪Sidelines Sports Bar and Grill - ‬6 min walk
  • ‪Hombre y Lobo - ‬17 min walk
  • ‪Pearl Street Grill & Brewery - ‬14 min walk
  • ‪Big Big Table - ‬19 min walk

About this property

Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG

Guests of Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG enjoy a gym, free WiFi in public areas, and a business center. Front-desk staff can answer questions 24/7, and assist with luggage storage, dry cleaning/laundry, and securing valuables. Additional amenities include express check-out, laundry facilities, and a vending machine.
Guests can expect free WiFi and 49-inch TVs with cable channels. Bathrooms have hair dryers and free toiletries. Other amenities include sofa beds, sitting areas, and refrigerators.
Recreational amenities at the hotel include a fitness center.

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Property amenities

Internet

  • Available in all rooms: Free WiFi
  • Available in some public areas: Free WiFi

Parking and transportation

  • Offsite parking available (USD 16 per day)
  • Wheelchair-accessible parking and van parking available
  • Onsite parking options include a garage

Food and drink

  • Free buffet breakfast available daily 6:00 AM to 10:00 AM

Things to do

  • Gym

Family friendly

  • In-room crib
  • In-room microwave
  • In-room refrigerator
  • In-room sofa bed
  • Laundry facilities
  • Living room
  • Separate bedroom

Conveniences

  • 24-hour front desk
  • Guidebooks
  • Laundry facilities
  • Luggage storage
  • Safe at front desk
  • Vending machine

Guest services

  • Dry cleaning/laundry service
  • Housekeeping (daily)

Business services

  • Business center

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Assistive listening devices
  • Elevator
  • Grab bar in shower
  • Grab bar near toilet
  • Hand-held showerhead
  • Handrails in stairways
  • Height-adjustable showerhead
  • In-room roll-in shower
  • Lever door handles
  • Low-height electrical outlets in bathroom
  • Portable shower seat
  • Raised toilet seat
  • Visual fire alarm
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible bathroom vanity
  • Wheelchair-accessible business center
  • Wheelchair-accessible gym
  • Wheelchair-accessible parking
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible path to elevator
  • Wheelchair-accessible public washroom
  • Wheelchair-accessible registration desk
  • Wheelchair-accessible restaurant
  • Wheelchair-accessible van parking

More

  • 7 floors
  • Comprehensive food waste policy
  • Eco-friendly cleaning products used
  • Smoking not allowed
  • Some LED lighting used
  • Vegetarian breakfast available
  • Vegetarian dining options

Room amenities

Bedroom

  • Bedsheets provided
  • Blackout drapes
  • Double sofa bed
  • Free crib

Bathroom

  • Free toiletries
  • Hair dryer
  • Private bathroom
  • Shower/bathtub combination
  • Towels provided

Entertainment

  • 49-inch TV with cable channels

Food and drink

  • Coffee/tea maker
  • Microwave
  • Refrigerator
  • Restaurant dining guides

More

  • Air conditioning (climate-controlled)
  • Bulk dispensers for toiletries
  • Connecting rooms available
  • Desk
  • Eco-friendly toiletries
  • Free local calls
  • Heating
  • Iron/ironing board
  • Laptop workspace
  • LED lighting
  • Living room
  • Phone
  • Safe
  • Separate sitting area

Policies

Check-in

Check-in start time: 3:00 PM; Check-in end time: anytime
Contactless check-in available
Minimum check-in age: 21

Check-out

Check-out before 11 AM
Contactless check-out available
Express check-out available

Special check-in instructions

Front desk staff will greet guests on arrival at the property
Information provided by the property may be translated using automated translation tools

Access methods

Staffed front desk

Pets

  • Service animals exempt from fees

Children and extra beds

  • Children 18 years old and younger stay free when using existing bedding
  • Free cribs/infant beds are available

Property payment types

Important information

Optional extras

These fees and deposits will be charged at check-in, check-out, or the time of service.

  • Nearby parking fee: USD 16.00 per day (500 ft away)

This list may not be comprehensive. Fees and deposits might not include tax and are subject to change.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
The name on the credit card used at check-in to pay for incidentals must be the primary name on the guestroom reservation
This property accepts credit cards; cash is not accepted
Safety features at this property include a fire extinguisher, a smoke detector, and window guards
This property affirms that it follows the cleaning and disinfection practices of Clean Promise (IHG)
Please note that cultural norms and guest policies may differ by country and by property; the policies listed are provided by the property
  • Check-in: 3:00 PM
  • Check-out: 11 AM
  • Minimum check-in age: 21
The front desk is open 24 hours a day, and checking out is easy with express services.

We should mention

Details about charges, deposits, or other important information:

  • This property is managed by a professional host. The provision of housing is linked to their trade, business, or profession.
  • Charges for extra guests may apply and vary depending on the property's policy.
  • A cash deposit, credit card, or debit card for incidental charges, as well as a government-issued photo ID, may be required at check-in.
  • Special requests are subject to availability at the time of check-in and can't be guaranteed. Certain requests may come with additional charges.
  • This property accepts credit cards. Cash is not accepted. 
  • The credit card used at check-in for incidentals must be in the name of the primary guest who made the reservation.
  • Onsite safety features include a fire extinguisher, a smoke detector, and window guards.
  • This property affirms that it follows the cleaning and disinfection practices of Clean Promise (IHG).

Additional information about polices, regulations, and more:

  • Registered guests are the only ones allowed in guestrooms.
  • Connecting or adjoining rooms can be requested, but all rooms are subject to availability. Contact the property using the phone number on your booking confirmation.
  • No rollaway or extra beds are available.
  • This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly).

Property is also known as

Holiday Inn Express Buffalo Downtown Hotel
Comfort Suites Hotel Downtown
Comfort Suites Downtown Hotel Buffalo
Comfort Suites Downtown Buffalo
Comfort Suites Downtown Buffalo Hotel
Comfort Suites Buffalo
Buffalo Comfort Suites
Holiday Inn Express Buffalo Downtown
Holiday Inn Express Suites Buffalo Downtown
Holiday Inn Express Suites Buffalo Downtown Medical CTR
Holiday Inn Express Suites Buffalo Downtown Medical CTR by IHG

Frequently asked questions

Is free cancellation available at Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG?

Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG offers free cancellation on select room rates. For additional details, take a look at the cancellation policy on Orbitz.

How much does it cost to stay at Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG?

As of Aug 23, 2026, prices found for a 1-night stay for 2 adults at Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG on Sep 20, 2026 start from $144, including taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.

What is there to do close to Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG?

This hotel is situated in Downtown Buffalo, just steps from Shea's Performing Arts Center and Buffalo Music Hall of Fame, and within a short walk of Niagara Square. You'll also find KeyBank Center and Lake Erie within a short drive.

Will I be able to park at Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG?

Yes, there is wheelchair-accessible van parking available.

Does Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG include a casino at the property?

No, Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG doesn't have a casino.

Is there an indoor pool at Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG?

No, there is no indoor pool at this hotel.

Is Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG good for couples?

Couples staying at this hotel will appreciate amenities like a free daily breakfast plus some guestrooms include a city view and free WiFi.

Are there hot tubs at Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG?

No, there isn't a spa tub at this hotel.

Does Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG have a restaurant that serves breakfast?

Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG offers free buffet breakfast each morning though there is no restaurant.

Does Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG allow pets to stay for free?

No, pets aren't allowed at Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG though service animals are welcome.

Are there connecting rooms at Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG?

Yes, this hotel has connecting rooms you can book for your group event or vacation.

Where is the closest airport to Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG?

The closest major airport to Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG is Buffalo Niagara Intl. Airport (BUF), which is 10.3 mi away (21 minutes by car). Another top airport is Niagara Falls, NY (IAG-Niagara Falls Intl.), which is located 22 mi away (30-minute drive).

Can I book a room with a balcony at Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG?

No, you won't find guestrooms with balconies at Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG.

Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG Reviews

Reviews

8.6

Excellent

Rating 10 - Excellent. 560 out of 1020 reviews
Rating 8 - Good. 270 out of 1020 reviews
Rating 6 - Okay. 87 out of 1020 reviews
Rating 4 - Poor. 44 out of 1020 reviews
Rating 2 - Terrible. 59 out of 1020 reviews

8.8/10

Cleanliness

8.8/10

Staff & service

8.2/10

Amenities

8.6/10

Property conditions & facilities

Reviews

Verified review

10/10 Excellent

Deb

Liked: Cleanliness, staff & service, property conditions & facilities
Great stay!
Stayed 1 night in May 2026
Verified review

8/10 Good

April

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great breakfast, nice big rooms!
Stayed 1 night in May 2026
Verified review

10/10 Excellent

Jeremiah

Liked: Cleanliness, staff & service, property conditions & facilities
good staff, breakfast was great
Stayed 1 night in May 2026
Verified review

10/10 Excellent

keyhan

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Clean room, staff was helpful and breakfast was fresh and delicious
Stayed 3 nights in Apr 2026
Verified review

8/10 Good

Juan

Liked: Cleanliness
Great location
Stayed 4 nights in May 2026
Verified review

10/10 Excellent

Andy

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Affordable and convenient hotel in downtown Buffalo with a good breakfast provided and a spacious room.
Stayed 2 nights in May 2026
Verified review

10/10 Excellent

Pratik

Clean room and friendly staff. Great location
Stayed 1 night in May 2026
Verified review

10/10 Excellent

Jack

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Clean room ( a bit dated), staff was extremely helpful & breakfast was awesome !
Stayed 3 nights in Apr 2026
Verified review

8/10 Good

Janine

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Breakfast was great and staff was friendly and helpful.
Stayed 2 nights in Mar 2026
Verified review

8/10 Good

Anna

Liked: Cleanliness
Disliked: Staff & service
Convenient location
Stayed 1 night in May 2026
Verified review

10/10 Excellent

David

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great hotel and great location with an awesome staff. Byron was especially friendly and helpful! Nice breakfast included as well.
Stayed 1 night in Apr 2026
Verified review

10/10 Excellent

Javier

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Tony at the front desk was so professional and helpful with recommendations. He made sure we had a nice stay during our time in Buffalo. Clean and spacious room.
Stayed 2 nights in May 2026
Verified review

8/10 Good

Tracie

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Didn't get a chance to get breakfast because the bed was so nice!
Stayed 3 nights in May 2026
Verified review

6/10 Okay

Patrick

Liked: Cleanliness, staff & service, property conditions & facilities
Good breakfast. Good coffee. Rooms are a good size and comfy. No onsight parking.
Stayed 1 night in May 2026
Verified review

10/10 Excellent

Ben

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Very well placed hotel for the theatre district in Buffalo as well as a few train stops down from where the Sabers play hockey. Great hotel and an awesome price!!
Stayed 1 night in Apr 2026
Verified review

10/10 Excellent

Joseph

Liked: Cleanliness, amenities, property conditions & facilities
Great Stay All Around!!! Great Friendly Staff, Close To Everything AAAAA+++++
Stayed 1 night in Jan 2026
Verified review

10/10 Excellent

Scott

Great room and stay for the money.
Stayed 1 night in Feb 2026
Verified review

10/10 Excellent

Rossana

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
On a business trip. Hotel was clean, comfortable and close to restaurants. there is an upscale Indian restaurant attached to the hotel. I did not try it, but it will be on my list for my next visit. The hotel is near hospitals and the Roswell Cancer Center which was an easy, safe and pleasant 20 minute walk. Definitely will stay here again. Thank you to all the staff for making my visit comfortable and pleasant.
Stayed 2 nights in May 2026
Verified review

10/10 Excellent

Amy

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
We were there for a concert at Town Ballroom which is two blocks away. Breakfast was good. Parking is a block away in a public parking garage.
Stayed 1 night in Mar 2026
Verified review

10/10 Excellent

Robert

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Easy and safe area to walk around.
Stayed 1 night in Mar 2026
Verified review

10/10 Excellent

Ellen

Liked: Cleanliness, staff & service, amenities
Very clean and friendly staff
Stayed 1 night in Feb 2026
Verified review

10/10 Excellent

Jenny

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Was great
Stayed 1 night in Mar 2026
Verified review

10/10 Excellent

Ryan

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Needs a facelift but the place is clean
Stayed 2 nights in May 2026
Verified review

8/10 Good

Corey

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Everything was great. Only complaint was the noise from the trolley.
Stayed 2 nights in May 2026
Verified review

10/10 Excellent

Joseph

Liked: Cleanliness, amenities, property conditions & facilities
Great service and great location
Stayed 1 night in Jan 2026

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