Book 5 Star Hotels in Southwest Florida

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Featured Southwest Florida 5 Stars Hotels

Kompose Boutique Hotel

Kompose Boutique Hotel

3 out of 5
965 University Pkwy Sarasota FL
Free Cancellation
Reserve now, pay when you stay
67.02 mi from city center
$138 nightly
The price is $156 total per night
$156 total
Jan 5 - Jan 6, 2026
Total with taxes and fees
At Kompose Boutique Hotel, guests enjoy an outdoor pool, a 24-hour gym, and free WiFi in public areas. Self parking is offered for USD 5.35 per night. The front desk has multilingual staff standing by 24 hours a day to assist with securing valuables and luggage storage. Additional amenities include a hot tub, a 24-hour business center, and a microwave in a common area.
Pool
Hot Tub
Naples Grande Beach Resort

Naples Grande Beach Resort

4.5 out of 5
475 Seagate Drive Naples FL
Free Cancellation
32.58 mi from city center
$466 nightly
The price is $518 total per night
$518 total
Jan 5 - Jan 6, 2026
Total with taxes and fees
Guests of Naples Grande Beach Resort have access to a full-service spa, 3 outdoor pools, and a 24-hour gym. Parking is available for USD 20 per night (USD 30 per night for valet parking), and there's also a free beach shuttle. The 24-hour front desk has multilingual staff ready to assist with dry cleaning/laundry, luggage storage, and tours or tickets. Other amenities at this beach resort include a sauna, outdoor tennis courts, and free WiFi in public areas.
Pool
Hot Tub
Sunseeker Resort Florida Gulf Coast, Curio Collection Hilton

Sunseeker Resort Florida Gulf Coast, Curio Collection Hilton

4 out of 5
5500 Sunseeker Way Punta Gorda FL
Free Cancellation
Reserve now, pay when you stay
24.98 mi from city center
$182 nightly
The price is $204 total per night
$204 total
Jan 9 - Jan 10, 2026
Total with taxes and fees
Guests of Sunseeker Resort Florida Gulf Coast, Curio Collection Hilton have access to a full-service spa, 2 outdoor pools, and a 24-hour gym. Parking is USD 25 per night (USD 32 per night for valet parking)—but if you prefer not to drive, catch a ride in the airport shuttle (available 24 hours) for USD 15.00 per person one-way. The 24-hour front desk has staff standing by to help with concierge services, luggage storage, and dry cleaning/laundry. If you like to take your furry friend along on your adventures, this pet-friendly property offers food and water bowls and an off-leash area. Other amenities at this spa resort include 2 hot tubs, meeting rooms, and a conference center.
Pool
Hot Tub
Lani Kai Beachfront Resort

Lani Kai Beachfront Resort

3.5 out of 5
1400 Estero Blvd Fort Myers Beach FL
Free Cancellation
Reserve now, pay when you stay
18.69 mi from city center
$155 nightly
The price is $173 total per night
$173 total
Jan 7 - Jan 8, 2026
Total with taxes and fees
Guests staying at Lani Kai Beachfront Resort enjoy an outdoor pool, a rooftop terrace, and free WiFi in public areas. Self parking is offered for USD 20.00 per night. The front desk is staffed 24 hours a day to help with luggage storage and securing valuables. Other amenities at this beach hotel include laundry facilities, a vending machine, and a gift shop.
Pool
Free WiFi
Compass Hotel by Margaritaville Anna Maria Sound

Compass Hotel by Margaritaville Anna Maria Sound

4 out of 5
12324 Manatee Avenue West Bradenton FL
Free Cancellation
Reserve now, pay when you stay
78.52 mi from city center
$228 nightly
The price is $258 total per night
$258 total
Jan 5 - Jan 6, 2026
Total with taxes and fees
At Compass Hotel by Margaritaville Anna Maria Sound, guests enjoy features like an outdoor pool, a 24-hour gym, and free WiFi in public areas. There's free parking if you drive. The 24-hour front desk has multilingual staff ready to assist with securing valuables, concierge services, and luggage storage. Additional amenities include conference space, coffee/tea in a common area, and a microwave in a common area.
Pool
Breakfast included
Margaritaville Beach Resort Fort Myers

Margaritaville Beach Resort Fort Myers

4 out of 5
251 Crescent Street Fort Myers Beach FL
18.71 mi from city center
At Margaritaville Beach Resort Fort Myers , guests enjoy a full-service spa, an outdoor pool, and a 24-hour gym. Valet parking is available for USD 35 per day. The front desk is staffed 24 hours a day to help with concierge services and dry cleaning/laundry. Other amenities at this beach hotel include free WiFi in public areas and a terrace.
Pool
Spa
Carlisle Inn

Carlisle Inn

3.5 out of 5
3727 Bahia Vista Sarasota FL
Free Cancellation
Reserve now, pay when you stay
61.67 mi from city center
$197 nightly
The price is $223 total per night
$223 total
Jan 5 - Jan 6, 2026
Total with taxes and fees
At Carlisle Inn, guests enjoy an outdoor pool, a 24-hour gym, and free WiFi in public areas. If you decide to drive, there's free parking. The 24-hour front desk has staff standing by to help with luggage storage, securing valuables, and dry cleaning/laundry. Additional amenities include meeting rooms, a conference center, and a 24-hour business center.
Pool
Breakfast included
Hyatt Vacation Club at Coconut Cove, Bonita Springs

Hyatt Vacation Club at Coconut Cove, Bonita Springs

4 out of 5
11800 Coconut Cove Drive Bonita Springs FL
Free Cancellation
19.19 mi from city center
$251 nightly
The price is $280 total per night
$280 total
Jan 6 - Jan 7, 2026
Total with taxes and fees
Guests of Hyatt Vacation Club at Coconut Cove, Bonita Springs enjoy 3 outdoor pools, a lazy river, and a children's pool. Free parking is available if you drive. The front desk has multilingual staff that can help with concierge services and securing valuables. Other amenities at this golf aparthotel include a gym, a sauna, and free WiFi in public areas.
Pool
Hot Tub
Sanibel Island Beach Resort

Sanibel Island Beach Resort

3 out of 5
1231 Middle Gulf Dr Sanibel FL
Free Cancellation
Reserve now, pay when you stay
23.08 mi from city center
$256 nightly
The price is $283 total per night
$283 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
Guests of Sanibel Island Beach Resort enjoy features like an outdoor pool, free WiFi in public areas, and a computer station. You can put free parking to good use if you drive. The front desk is staffed 24/7 to help with luggage storage, dry cleaning/laundry, and concierge services. Other amenities at this beach hotel include a terrace, laundry facilities, and a garden.
Pool
Pet friendly
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Best 5 star hotels in Southwest Florida

Guarantee yourself a relaxing time when you book the best of the best: 5 star hotels in Southwest Florida. After all, treating yourself to the finer things is what vacations are about. 

What are the criteria for a 5 star hotel?
5 star hotel requirements include distinctive services and amenities that surpass all others. These Southwest Florida hotels bring an incomparable degree of quality and attention to detail, with guest satisfaction being top priority. Your 5 star hotel should be dressed to impress, with design details like marble surfaces and hi-tech fixtures.

What amenities can I expect at a 5 star hotel?
Southwest Florida 5 star hotels and resorts typically offer luxury amenities such as:

  • Gourmet restaurant
  • Full-service fitness center with pool
  • Luxury spa 
  • Welcome gifts upon arrival
  • Top-of-the-line beds and linens 
  • Designer personal care products
  • Premium cable, free Wi-Fi and device docking stations

How do I find an amazing 5 star hotel?
Finding 5 star hotel deals in Southwest Florida with Orbitz is as easy as your stay will be. For the top-shelf vacation you deserve, we’ll help you choose the right hotel in the right place: 

  • Search hotels by price, ranging from $156 to $518
  • Find the best-loved hotels through word-of-mouth advice when you check out over reviews by Orbitz travelers
  • Choose from 46,436 5 star hotels in Southwest Florida!

Southwest Florida hotels essential information

Accommodation
46,436 hotels
Lowest Price
$156
Highest Price
$518
Popular hotels
Kompose Boutique Hotel, Naples Grande Beach Resort, Sunseeker Resort Florida Gulf Coast, Curio Collection Hilton, Lani Kai Beachfront Resort, Compass Hotel by Margaritaville Anna Maria Sound, Margaritaville Beach Resort Fort Myers , Carlisle Inn, Hyatt Vacation Club at Coconut Cove, Bonita Springs, Sanibel Island Beach Resort

Recent Reviews

Sunseeker Resort Florida Gulf Coast, Curio Collection Hilton

Sunseeker Resort Florida Gulf Coast, Curio Collection Hilton

5/5 Excellent
"Everything was very nice and kept up well. Food was great everywhere."
A verified traveler stayed at Sunseeker Resort Florida Gulf Coast, Curio Collection Hilton
Posted 23 hours ago
Sunseeker Resort Florida Gulf Coast, Curio Collection Hilton

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