Cheap flights from FSD to RSW (Sioux Falls Regional to Southwest Florida Intl.)

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Cheap Flights from FSD to RSW starting at $117 One Way, $244 Round Trip

Prices starting at $244 for return flights and $117 for one-way flights to Southwest Florida Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Thu, Mar 5 - Thu, Mar 12
FSD
Sioux Falls
RSW
Fort Myers
$244 Roundtrip, found 2 days ago
$244
Roundtrip
found 2 days ago
Select Frontier Airlines flight, departing Thu, Mar 5 from Sioux Falls to Fort Myers, returning Thu, Mar 12, priced at $244 found 2 days ago
Tue, Apr 14 - Wed, Apr 29
FSD
Sioux Falls
RSW
Fort Myers
$259 Roundtrip, found 6 days ago
$259
Roundtrip
found 6 days ago
Select Delta flight, departing Tue, Apr 14 from Sioux Falls to Fort Myers, returning Wed, Apr 29, priced at $259 found 6 days ago
Sat, Apr 18 - Wed, Apr 29
FSD
Sioux Falls
RSW
Fort Myers
$261 Roundtrip, found 6 days ago
$261
Roundtrip
found 6 days ago
Select Delta flight, departing Sat, Apr 18 from Sioux Falls to Fort Myers, returning Wed, Apr 29, priced at $261 found 6 days ago
Sat, May 2 - Sat, May 16
FSD
Sioux Falls
RSW
Fort Myers
$264 Roundtrip, found 6 days ago
$264
Roundtrip
found 6 days ago
Select Delta flight, departing Sat, May 2 from Sioux Falls to Fort Myers, returning Sat, May 16, priced at $264 found 6 days ago
Tue, Apr 28 - Sat, May 16
FSD
Sioux Falls
RSW
Fort Myers
$266 Roundtrip, found 6 days ago
$266
Roundtrip
found 6 days ago
Select Delta flight, departing Tue, Apr 28 from Sioux Falls to Fort Myers, returning Sat, May 16, priced at $266 found 6 days ago

Hotel Ideas near Southwest Florida Intl.

Airport Hotels near Southwest Florida Intl.

Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park

Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park

2 out of 5
10150 Daniels Pkwy Fort Myers FL
$109 nightly
The price is $121 total per night from Feb 22 to Feb 23
$121 total
Feb 22 - Feb 23
Total with taxes and fees
Book a stay at this business-friendly hotel in Fort Myers. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the clean rooms ...
8/10 Very Good! (1,572 reviews)
Nice clean spacious room

Reviewed on Feb 3, 2026

Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park
Holiday Inn Express & Suites Fort Myers Airport by IHG

Holiday Inn Express & Suites Fort Myers Airport by IHG

2.5 out of 5
14567 GLOBAL PARKWAY Fort Myers FL
$178 nightly
The price is $198 total per night from Mar 1 to Mar 2
$198 total
Mar 1 - Mar 2
Total with taxes and fees
Book a stay at this business-friendly hotel in Fort Myers. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9.4/10 Exceptional! (1,009 reviews)
Nice staff

Reviewed on Feb 5, 2026

Holiday Inn Express & Suites Fort Myers Airport by IHG
Comfort Inn & Suites Fort Myers Airport

Comfort Inn & Suites Fort Myers Airport

2.5 out of 5
Fort Myers FL
$152 nightly
The price is $170 total per night from Feb 15 to Feb 16
$170 total
Feb 15 - Feb 16
Total with taxes and fees
Book a stay at this business-friendly hotel in Fort Myers. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (1,123 reviews)
Yes

Reviewed on Feb 6, 2026

Comfort Inn & Suites Fort Myers Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In Fort Myers

Marriott Sanibel Harbour Resort & Spa

Marriott Sanibel Harbour Resort & Spa

4 out of 5
17260 Harbour Pointe Dr Fort Myers FL
$421 nightly
The price is $470 total per night from Feb 12 to Feb 13
$470 total
Feb 12 - Feb 13
Total with taxes and fees
Book a stay at this spa resort in Fort Myers. Enjoy 3 outdoor pools, a full-service spa, and 4 restaurants. Our guests praise the helpful staff and the property ...
8.4/10 Very Good! (1,000 reviews)
Nice room and perfect location

Reviewed on Feb 1, 2026

Marriott Sanibel Harbour Resort & Spa
Baymont by Wyndham Fort Myers Central

Baymont by Wyndham Fort Myers Central

2.5 out of 5
4850 S Cleveland Ave Fort Myers FL
$104 nightly
The price is $115 total per night from Mar 1 to Mar 2
$115 total
Mar 1 - Mar 2
Total with taxes and fees
Book a stay at this business-friendly hotel in Fort Myers. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
6.6/10 (1,007 reviews)
Great Location close to the beach

Reviewed on Feb 5, 2026

Baymont by Wyndham Fort Myers Central
Hilton Garden Inn Ft Myers

Hilton Garden Inn Ft Myers

3 out of 5
12600 University Dr Fort Myers FL
$207 nightly
The price is $231 total per night from Feb 15 to Feb 16
$231 total
Feb 15 - Feb 16
Total with taxes and fees
Book a stay at this business-friendly hotel in Fort Myers. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our ...
8.6/10 Excellent! (1,006 reviews)
Clean, friendly, helpful, heated clean pool, great made-to-order breakfasts…OUTSTANDING!!

Reviewed on Feb 3, 2026

Hilton Garden Inn Ft Myers
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Fort Myers Hotels With Airport Transportation

Crowne Plaza Ft. Myers Gulf Coast by IHG

Crowne Plaza Ft. Myers Gulf Coast by IHG

4 out of 5
9931 Interstate Commerce Dr Fort Myers FL
$280 nightly
The price is $312 total per night from Feb 16 to Feb 17
$312 total
Feb 16 - Feb 17
Total with taxes and fees
Book a stay at this business-friendly hotel in Fort Myers. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and ...
9/10 Wonderful! (1,000 reviews)
The staff

Reviewed on Feb 2, 2026

Crowne Plaza Ft. Myers Gulf Coast by IHG
Travelodge by Wyndham Fort Myers Airport

Travelodge by Wyndham Fort Myers Airport

2 out of 5
13661 Indian Paint Lane Fort Myers FL
$91 nightly
The price is $101 total per night from Mar 1 to Mar 2
$101 total
Mar 1 - Mar 2
Total with taxes and fees
Book a stay at this business-friendly hotel in Fort Myers. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the ...
7.4/10 Good! (1,003 reviews)
allgood

Reviewed on Feb 8, 2026

Travelodge by Wyndham Fort Myers Airport
Baymont by Wyndham Fort Myers Airport

Baymont by Wyndham Fort Myers Airport

2.5 out of 5
9401 Marketplace Road Fort Myers FL
$104 nightly
The price is $116 total per night from Mar 1 to Mar 2
$116 total
Mar 1 - Mar 2
Total with taxes and fees
Book a stay at this business-friendly hotel in Fort Myers. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
6/10 (1,006 reviews)
Clean rooms great service will use again

Reviewed on Feb 6, 2026

Baymont by Wyndham Fort Myers Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced Fort Myers Hotels

Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park

Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park

2 out of 5
10150 Daniels Pkwy Fort Myers FL
$109 nightly
The price is $121 total per night from Feb 22 to Feb 23
$121 total
Feb 22 - Feb 23
Total with taxes and fees
Book a stay at this business-friendly hotel in Fort Myers. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the clean rooms ...
8/10 Very Good! (1,572 reviews)
Nice clean spacious room

Reviewed on Feb 3, 2026

Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park
Travelodge by Wyndham Fort Myers North

Travelodge by Wyndham Fort Myers North

2 out of 5
13353 N Cleveland Ave North Fort Myers FL
$76 nightly
The price is $84 total per night from Feb 15 to Feb 16
$84 total
Feb 15 - Feb 16
Total with taxes and fees
Stay at this hotel in North Fort Myers. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Edison Mall and Centennial Park are located ...
5.8/10 (1,001 reviews)
1st and formost, one of the employees at the front desk reeked of marijuana when I checked-in. Bed was never made the entire 4-night stay, the trash wasn’t emptied nor were the towels refreshed the last night of my stay, cockroaches running around on the floor, the small round ones that you bring ...

Reviewed on Feb 6, 2026

Travelodge by Wyndham Fort Myers North
Baymont by Wyndham Fort Myers Airport

Baymont by Wyndham Fort Myers Airport

2.5 out of 5
9401 Marketplace Road Fort Myers FL
$104 nightly
The price is $116 total per night from Mar 1 to Mar 2
$116 total
Mar 1 - Mar 2
Total with taxes and fees
Book a stay at this business-friendly hotel in Fort Myers. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
6/10 (1,006 reviews)
Clean rooms great service will use again

Reviewed on Feb 6, 2026

Baymont by Wyndham Fort Myers Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Fort Myers

Pink Shell Beach Resort and Marina

Pink Shell Beach Resort and Marina

4 out of 5
275 Estero Blvd Fort Myers Beach FL
$493 nightly
The price is $550 total per night from Feb 10 to Feb 11
$550 total
Feb 10 - Feb 11
Total with taxes and fees
Book a stay at this beach resort in Fort Myers Beach. Enjoy free breakfast, 3 outdoor pools, and 3 restaurants. Our guests praise the breakfast and the pool ...
9.4/10 Exceptional! (1,257 reviews)
Clean and modern room. Great view of the beach!

Reviewed on Feb 3, 2026

Pink Shell Beach Resort and Marina
Sundial Beach Resort & Spa

Sundial Beach Resort & Spa

5 out of 5
1451 Middle Gulf Drive Sanibel FL
$579 nightly
The price is $646 total per night from Feb 10 to Feb 11
$646 total
Feb 10 - Feb 11
Total with taxes and fees
Book a stay at this luxury condo in Sanibel. Enjoy free WiFi, free parking, and 2 outdoor pools. Our guests praise the property condition in our reviews. Popular ...
8.6/10 Excellent! (2,596 reviews)
Very clean room, staff was very nice. All of the pools were clean and everything was very nice and well taken care of.

Reviewed on Jan 30, 2026

Sundial Beach Resort & Spa
South Seas Resort

South Seas Resort

3.5 out of 5
5400 South Seas Plantation Rd Captiva FL
$568 nightly
The price is $634 total per night from Feb 10 to Feb 11
$634 total
Feb 10 - Feb 11
Total with taxes and fees
Book a stay at this beach resort in Captiva. Enjoy 3 outdoor pools, 7 restaurants, and a private beach. Popular attractions Jungle Drums and McCarthy's Marina ...
8.2/10 Very Good! (1,000 reviews)

Families like: Outdoor pools, waterslide, kitchen, on the beach

Travelers say...
It was an incredible room with tremendous staff.

Reviewed on Feb 3, 2026

South Seas Resort
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

FSD to RSW Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date

Frequently asked questions

Are there non-stop flights from Joe Foss Field to RSW?
You'll need to swap planes if you're wanting to fly from Sioux Falls Regional Airport (FSD) to RSW. A number of airlines offer services on this route with just one stopover, including Delta Air Lines, United Airlines and American Airlines.
What is the shortest flight from Joe Foss Field to Southwest Florida Intl. Airport (RSW)?
From Sioux Falls, the exciting sights and sounds of Fort Myers are 4 hours and 49 minutes away. Lock in your favorite seat, or perhaps even upgrade to one with a little more legroom, and travel to your destination in pure comfort.
How many hours flight from Sioux Falls Regional Airport (FSD) to Southwest Florida Intl. Airport (RSW)?
The journey from Joe Foss Field to Southwest Florida Intl. Airport will take an average of 4 hours and 58 minutes. A few good movies, some audiobooks and a long nap will make the time fly.
What airlines have the most flights from Joe Foss Field to RSW?
At the moment, no airlines offer direct flights from Joe Foss Field to Southwest Florida Intl. Airport. But don't panic! There are lots of single or multi-stop options available.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.