$207 Cheap flight deals from Cali (CLO) to Panama City (PTY)

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This Weekend's Flight Deals from Cali to Panama City

This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Fri, Jun 5 - Mon, Jun 8
CLO
Alfonso Bonilla Aragon Intl.
PTY
Tocumen Intl.
$358 Roundtrip, found 1 day ago
$358
Roundtrip
found 1 day ago
Select Copa flight, departing Fri, Jun 5 from Alfonso Bonilla Aragon Intl. to Tocumen Intl., returning Mon, Jun 8, priced at $358 found 1 day ago

Airfares from $207 One Way, $358 Round Trip from Cali to Panama City

Prices starting at $358 for return flights and $207 for one-way flights to Panama City were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Fri, Oct 9 - Tue, Oct 13
CLO
Cali
PTY
Panama City
$358 Roundtrip, found 23 hours ago
$358
Roundtrip
found 23 hours ago
Select Copa flight, departing Fri, Oct 9 from Cali to Panama City, returning Tue, Oct 13, priced at $358 found 23 hours ago
Fri, Oct 9 - Tue, Oct 13
CLO
Cali
PTY
Panama City
$396 Roundtrip, found 23 hours ago
$396
Roundtrip
found 23 hours ago
Select avianca flight, departing Fri, Oct 9 from Cali to Panama City, returning Tue, Oct 13, priced at $396 found 23 hours ago
Fri, Oct 9 - Tue, Oct 13
CLO
Cali
PTY
Panama City
$400 Roundtrip, found 23 hours ago
$400
Roundtrip
found 23 hours ago
Select avianca flight, departing Fri, Oct 9 from Cali to Panama City, returning Tue, Oct 13, priced at $400 found 23 hours ago
Fri, Oct 9 - Tue, Oct 13
CLO
Cali
PTY
Panama City
$404 Roundtrip, found 23 hours ago
$404
Roundtrip
found 23 hours ago
Select Copa flight, departing Fri, Oct 9 from Cali to Panama City, returning Tue, Oct 13, priced at $404 found 23 hours ago
Mon, Sep 7 - Fri, Sep 11
CLO
Cali
PTY
Panama City
$409 Roundtrip, found 5 days ago
$409
Roundtrip
found 5 days ago
Select avianca flight, departing Mon, Sep 7 from Cali to Panama City, returning Fri, Sep 11, priced at $409 found 5 days ago

Panama City economy flight packages

Price found within the past 48 hours. Click for updated prices.
Hotel Riu Plaza Panama
5.0-star property

Hotel Riu Plaza Panama

9/10 Wonderful! (5,488 reviews)

Jul 17 - Jul 20

3 night stay

Cali (CLO) to Panama City (PTY)

Copa • Roundtrip • Coach
Price was $730, price is now $535 per person
$535
per person
found 11 hours ago
Todo limpio buen trato personal amable muy confortable el bufet muy bueno toda variedad y buena higiene en fin la pasamos espectacular

Reviewed on May 16, 2026

Central Hotel Panama Casco Viejo
4.0-star property

Central Hotel Panama Casco Viejo

9.2/10 Wonderful! (1,003 reviews)

Jul 17 - Jul 20

3 night stay

Cali (CLO) to Panama City (PTY)

Copa • Roundtrip • Coach
Save 100% on your flight
Price was $1,027, price is now $615 per person
$615
per person
found 11 hours ago
Good breakfast. Perfect location. Big rooms. All good.

Reviewed on Apr 13, 2026

Megapolis Hotel Panamá
4.5-star property

Megapolis Hotel Panamá

8.4/10 Very Good! (1,538 reviews)

Jul 17 - Jul 20

3 night stay

Cali (CLO) to Panama City (PTY)

Copa • Roundtrip • Coach
Price was $869, price is now $608 per person
$608
per person
found 11 hours ago
Room was very clean, breakfast was great.Easy check in.

Reviewed on Nov 16, 2025

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More About Flying To Panama City from Cali

Route Information for Flights from Cali to Panama City

Origin Airport IATA Code
CLO
Destination Airport IATA Code
PTY
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

Cali to Panama City

For the best available deals on flights from Cali to Panama City, look no further than Orbitz. Offering the perfect packages with cutting-edge mobile tools, Orbitz is your ideal destination.

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Frequently asked questions

Are there non-stop flights from Cali to Panama City?
Copa Airlines flies nonstop from Cali to Panama City, so all you have to do is sit back and relax until you land at PTY.
What is the shortest flight from Cali to Panama City?
Leave that epic movie for another time, because the flight from CLO to Panama Airport can be as quick as 1 hour and 29 minutes.
What airlines fly from Cali to Panama City most frequently?
If you're looking for the airline with the most flights from Cali to Panama City, Copa Airlines is your best bet. This quality airline operates 104 flights along this route per month.
What is the cheapest day of the week to fly?
Consider flying out early in the week to save on your airfare. Orbitz data from 2021 shows that Monday is the cheapest day to depart, followed by Tuesday. Saturday showed the highest average ticket prices likely because many travelers prefer to start their vacation on a weekend.
What is the cheapest month to fly?
We won't keep you guessing, according to Orbitz data from 2021, the cheapest month to fly is February. Perfect for those who need a weekend getaway, or just a break from it all in the shortest month of the year. Be aware that the most expensive time to fly is during the height of summer in July, and in the holiday month of December.*According to flight demand on Orbitz.com from January to December 2021. Savings are subject to change based on departure location, date and destination.

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Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.