$206 Cheap flight deals from Cali (CLO) to Panama City (PTY)

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This Weekend's Flight Deals from Cali to Panama City

This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sun, Jun 21 - Wed, Sep 2
CLO
Alfonso Bonilla Aragon Intl.
PTY
Tocumen Intl.
$397 Roundtrip, found 2 days ago
$397
Roundtrip
found 2 days ago
Select avianca flight, departing Sun, Jun 21 from Alfonso Bonilla Aragon Intl. to Tocumen Intl., returning Wed, Sep 2, priced at $397 found 2 days ago

Airfares from $206 One Way, $362 Round Trip from Cali to Panama City

Prices starting at $362 for return flights and $206 for one-way flights to Panama City were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Thu, Jul 30 - Thu, Aug 6
CLO
Cali
PTY
Panama City
$362 Roundtrip, found 5 days ago
$362
Roundtrip
found 5 days ago
Select avianca flight, departing Thu, Jul 30 from Cali to Panama City, returning Thu, Aug 6, priced at $362 found 5 days ago
Mon, Aug 3 - Fri, Aug 21
CLO
Cali
PTY
Panama City
$363 Roundtrip, found 2 hours ago
$363
Roundtrip
found 2 hours ago
Select avianca flight, departing Mon, Aug 3 from Cali to Panama City, returning Fri, Aug 21, priced at $363 found 2 hours ago
Wed, Aug 19 - Wed, Aug 26
CLO
Cali
PTY
Panama City
$373 Roundtrip, found 6 days ago
$373
Roundtrip
found 6 days ago
Select avianca flight, departing Wed, Aug 19 from Cali to Panama City, returning Wed, Aug 26, priced at $373 found 6 days ago
Mon, Aug 3 - Fri, Aug 21
CLO
Cali
PTY
Panama City
$374 Roundtrip, found 2 hours ago
$374
Roundtrip
found 2 hours ago
Select avianca flight, departing Mon, Aug 3 from Cali to Panama City, returning Fri, Aug 21, priced at $374 found 2 hours ago
Wed, Aug 19 - Wed, Aug 26
CLO
Cali
PTY
Panama City
$384 Roundtrip, found 6 days ago
$384
Roundtrip
found 6 days ago
Select avianca flight, departing Wed, Aug 19 from Cali to Panama City, returning Wed, Aug 26, priced at $384 found 6 days ago

Panama City economy flight packages

Price found within the past 48 hours. Click for updated prices.
Riande Aeropuerto Hotel & Casino
4.0-star property

Riande Aeropuerto Hotel & Casino

8.4/10 Very Good! (1,825 reviews)

Aug 7 - Aug 10

3 night stay

Cali (CLO) to Panama City (PTY)

Copa • Roundtrip • Coach
Price was $741, price is now $516 per person
$516
per person
found 2 hours ago
The AC unit stopped working which made it difficult to sleep. There were bugs in the bathroom. The lobby and pool area is nice but the rooms need to be renovated with new window shades, sinks, showers, furniture, paint and beds. The beds were also lumpy.

Reviewed on May 30, 2026

Megapolis Hotel Panamá
4.5-star property

Megapolis Hotel Panamá

8.4/10 Very Good! (1,553 reviews)

Aug 7 - Aug 10

3 night stay

Cali (CLO) to Panama City (PTY)

Copa • Roundtrip • Coach
Price was $872, price is now $565 per person
$565
per person
found 2 hours ago
Room was very clean, breakfast was great.Easy check in.

Reviewed on Nov 16, 2025

Hotel Riu Plaza Panama
5.0-star property

Hotel Riu Plaza Panama

9/10 Wonderful! (5,582 reviews)

Aug 7 - Aug 10

3 night stay

Cali (CLO) to Panama City (PTY)

Copa • Roundtrip • Coach
Price was $754, price is now $546 per person
$546
per person
found 2 hours ago
Todo limpio buen trato personal amable muy confortable el bufet muy bueno toda variedad y buena higiene en fin la pasamos espectacular

Reviewed on May 16, 2026

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More About Flying To Panama City from Cali

Route Information for Flights from Cali to Panama City

Origin Airport IATA Code
CLO
Destination Airport IATA Code
PTY
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

Cali to Panama City

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Frequently asked questions

Are there non-stop flights from Cali to Panama City?
Copa Airlines flies nonstop from Cali to Panama City, so all you have to do is sit back and relax until you land at PTY.
What is the shortest flight from Cali to Panama City?
Leave that epic movie for another time, because the flight from CLO to Panama Airport can be as quick as 1 hour and 29 minutes.
What airlines fly from Cali to Panama City most frequently?
If you're looking for the airline with the most flights from Cali to Panama City, Copa Airlines is your best bet. This quality airline operates 104 flights along this route per month.
What is the cheapest day of the week to fly?
Consider flying out early in the week to save on your airfare. Orbitz data from 2021 shows that Monday is the cheapest day to depart, followed by Tuesday. Saturday showed the highest average ticket prices likely because many travelers prefer to start their vacation on a weekend.
What is the cheapest month to fly?
We won't keep you guessing, according to Orbitz data from 2021, the cheapest month to fly is February. Perfect for those who need a weekend getaway, or just a break from it all in the shortest month of the year. Be aware that the most expensive time to fly is during the height of summer in July, and in the holiday month of December.*According to flight demand on Orbitz.com from January to December 2021. Savings are subject to change based on departure location, date and destination.

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Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.