$37 Cheap flight deals from Cali (CLO) to Medellín (MDE)

Earn rewards on top of your airline miles with Orbitz Rewards

Many airlines offer flexible change policies

Sign up to receive text alerts about your trip

This Weekend's Flight Deals from Cali to Medellín

This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Fri, May 29 - Sun, May 31
CLO
Alfonso Bonilla Aragon Intl.
MDE
José María Córdova Intl.
$114 Roundtrip, found 4 days ago
$114
Roundtrip
found 4 days ago
Select Jetsmart SPA flight, departing Fri, May 29 from Alfonso Bonilla Aragon Intl. to José María Córdova Intl., returning Sun, May 31, priced at $114 found 4 days ago

Airfares from $37 One Way, $73 Round Trip from Cali to Medellín

Prices starting at $73 for return flights and $37 for one-way flights to Medellín were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sat, Jul 4 - Fri, Jul 10
CLO
Cali
MDE
Medellín
$73 Roundtrip, found 5 days ago
$73
Roundtrip
found 5 days ago
Select Jetsmart SPA flight, departing Sat, Jul 4 from Cali to Medellín, returning Fri, Jul 10, priced at $73 found 5 days ago
Thu, Sep 10 - Wed, Sep 16
CLO
Cali
MDE
Medellín
$73 Roundtrip, found 1 day ago
$73
Roundtrip
found 1 day ago
Select Jetsmart SPA flight, departing Thu, Sep 10 from Cali to Medellín, returning Wed, Sep 16, priced at $73 found 1 day ago
Sat, Jul 18 - Fri, Jul 24
CLO
Cali
MDE
Medellín
$74 Roundtrip, found 6 days ago
$74
Roundtrip
found 6 days ago
Select Jetsmart SPA flight, departing Sat, Jul 18 from Cali to Medellín, returning Fri, Jul 24, priced at $74 found 6 days ago
Mon, Jun 22 - Mon, Jun 29
CLO
Cali
MDE
Medellín
$75 Roundtrip, found 13 hours ago
$75
Roundtrip
found 13 hours ago
Select Jetsmart SPA flight, departing Mon, Jun 22 from Cali to Medellín, returning Mon, Jun 29, priced at $75 found 13 hours ago
Wed, Aug 19 - Sun, Aug 23
CLO
Cali
MDE
Medellín
$80 Roundtrip, found 1 day ago
$80
Roundtrip
found 1 day ago
Select Jetsmart SPA flight, departing Wed, Aug 19 from Cali to Medellín, returning Sun, Aug 23, priced at $80 found 1 day ago

Medellín economy flight packages

Price found within the past 48 hours. Click for updated prices.
Autenthico Sajonia Hotel Aeropuerto
2.0-star property

Autenthico Sajonia Hotel Aeropuerto

9.4/10 Exceptional! (79 reviews)

Jul 5 - Jul 8

3 night stay

Cali (CLO) to Medellín (MDE)

B & H Airlines • Roundtrip • Coach
Save 100% on your flight
Price was $367, price is now $196 per person
$196
per person
found 13 hours ago
Devú
5.0-star property

Devú

10/10 Exceptional! (4 reviews)

Jul 5 - Jul 8

3 night stay

Cali (CLO) to Medellín (MDE)

B & H Airlines • Roundtrip • Coach
Price was $681, price is now $294 per person
$294
per person
found 13 hours ago
The Charlee Hotel
5.0-star property

The Charlee Hotel

8.8/10 Excellent! (1,006 reviews)

Jul 5 - Jul 8

3 night stay

Cali (CLO) to Medellín (MDE)

B & H Airlines • Roundtrip • Coach
Save 100% on your flight
Price was $639, price is now $330 per person
$330
per person
found 13 hours ago
Eddie was amazingggg!!! All of the staff was so kind and so helpful. Excellent location! The restaurant food was very good.

Reviewed on Apr 28, 2026

Don't see what you're looking for?
See all available trips from Cali to Medellín
View all trips

More About Flying To Medellín from Cali

Route Information for Flights from Cali to Medellín

Origin Airport IATA Code
CLO
Destination Airport IATA Code
MDE
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

Cali to Medellín

The best fares for Cali to Medellín flights are always found on Orbitz. With superior discounts and the latest innovations in mobile access, your ideal trip starts with Orbitz.

The Easy Way to Plan Travel Cheaply

We provide access to many low-cost vacation packages and travelers can mix and match airlines when scheduling their flights for the best prices and flight times. Finding cheap tickets on flights from Cali to Medellín is easy when you make Orbitz your #1 travel planner.

Book Cali to Medellín Flights With Mobile Apps

Our iPhone and Android mobile apps can be used to compare and book flights from Cali to Medellín. These apps are perfect for checking the status of flights, gate and baggage claims details, car rental rates, and for receiving alerts on special savings that are exclusive to mobile users. Mobile app users can even score great rates when booking hotel rooms. You can compare hotels, virtually view photo galleries, and check out user reviews using the app, as well as find out which ones are closest to you.

Orbitz also offers free travel updates that are sent to your email or mobile phone that notifies you of booking changes, disruptions in service, or delayed flights.

Increase Your Rewards While Enjoying Super Low Rates

Boost your points or miles for your frequent flyer program on certain Cali to Medellín flights. Simply provide your frequent flyer information when booking flights from Cali to Medellín with Orbitz and get both a low fare and travel rewards. You can enter this information in your Orbitz account profile for easy remembering in future bookings.

Frequently asked questions

Are there non-stop flights from Cali to Medellin?
There are 3 airlines that offer nonstop services from Cali Airport to Medellin (MDE-Jose Maria Cordova Intl.), so get ready to hit that "book" button. One of these carriers will have the flight you're looking for:

  • LATAM Airlines
  • Viva Air Colombia
  • Avianca

What is the shortest flight from Cali to Medellin?
If the weather is good and all goes as scheduled, you could be coming in to land at Medellin (MDE-Jose Maria Cordova Intl.) from Alfonso Bonilla Aragon Intl. Airport (CLO) in only 49 minutes. With such a speedy flight time, contemplate taking hand luggage only.
What airlines fly from Cali to Medellin most frequently?
The airlines that fly frequently between Cali Airport and MDE include LATAM Airlines (LA). This well-known option offers 86 flights on the route each month. Viva Air Colombia (VH) will also take you to your destination in comfort. Offering 69 flights every month between Cali and Medellin, it's another popular airline to look into.
What is the cheapest day of the week to fly?
Consider flying out early in the week to save on your airfare. Orbitz data from 2021 shows that Monday is the cheapest day to depart, followed by Tuesday. Saturday showed the highest average ticket prices likely because many travelers prefer to start their vacation on a weekend.
What is the cheapest month to fly?
We won't keep you guessing, according to Orbitz data from 2021, the cheapest month to fly is February. Perfect for those who need a weekend getaway, or just a break from it all in the shortest month of the year. Be aware that the most expensive time to fly is during the height of summer in July, and in the holiday month of December.*According to flight demand on Orbitz.com from January to December 2021. Savings are subject to change based on departure location, date and destination.

More Destinations

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.