$19 Cheap flight deals from Cali (CLO) to Medellin (MDE)

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This Weekend's Flight Deals from Cali to Medellin

This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sun, Jan 4 - Thu, Jan 8
CLO
Alfonso Bonilla Aragon Intl.
MDE
José María Córdova Intl.
$128 Roundtrip, found 1 hour ago
$128
Roundtrip
found 1 hour ago
Select avianca flight, departing Sun, Jan 4 from Alfonso Bonilla Aragon Intl. to José María Córdova Intl., returning Thu, Jan 8, priced at $128 found 1 hour ago

Airfares from $19 One Way, $37 Round Trip from Cali to Medellin

Prices starting at $37 for return flights and $19 for one-way flights to Medellin were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Fri, Apr 10 - Thu, Apr 16
CLO
Cali
MDE
Medellin
$37 Roundtrip, found 2 days ago
$37
Roundtrip
found 2 days ago
Select Jetsmart SPA flight, departing Fri, Apr 10 from Cali to Medellin, returning Thu, Apr 16, priced at $37 found 2 days ago
Tue, Feb 3 - Fri, Feb 6
CLO
Cali
MDE
Medellin
$37 Roundtrip, found 6 days ago
$37
Roundtrip
found 6 days ago
Select Jetsmart SPA flight, departing Tue, Feb 3 from Cali to Medellin, returning Fri, Feb 6, priced at $37 found 6 days ago
Sun, Feb 1 - Sat, Feb 7
CLO
Cali
MDE
Medellin
$57 Roundtrip, found 6 days ago
$57
Roundtrip
found 6 days ago
Select Jetsmart SPA flight, departing Sun, Feb 1 from Cali to Medellin, returning Sat, Feb 7, priced at $57 found 6 days ago
Mon, Apr 27 - Sun, May 3
CLO
Cali
MDE
Medellin
$57 Roundtrip, found 11 hours ago
$57
Roundtrip
found 11 hours ago
Select Jetsmart SPA flight, departing Mon, Apr 27 from Cali to Medellin, returning Sun, May 3, priced at $57 found 11 hours ago
Mon, Feb 2 - Thu, Feb 5
CLO
Cali
MDE
Medellin
$58 Roundtrip, found 1 day ago
$58
Roundtrip
found 1 day ago
Select Jetsmart SPA flight, departing Mon, Feb 2 from Cali to Medellin, returning Thu, Feb 5, priced at $58 found 1 day ago

Medellin economy flight packages

Price found within the past 48 hours. Click for updated prices.
Hotel Attic 33
3.0-star property

Hotel Attic 33

No reviews

Feb 9 - Feb 16

7 night stay

Cali (CLO) to Medellín (MDE)

B & H Airlines • Roundtrip • Coach
Save 100% on your flight
Price was $345, price is now $170 per person
$170
per person
found 1 day ago
Calle Flora Hotel by Jalo
3.5-star property

Calle Flora Hotel by Jalo

9.2/10 Wonderful! (231 reviews)

Feb 9 - Feb 16

7 night stay

Cali (CLO) to Medellín (MDE)

B & H Airlines • Roundtrip • Coach
Price was $452, price is now $195 per person
$195
per person
found 1 day ago
Everything was perfect!

Reviewed on Nov 5, 2025

Blues Suites Medellin
4.0-star property

Blues Suites Medellin

9/10 Wonderful! (981 reviews)

Feb 9 - Feb 16

7 night stay

Cali (CLO) to Medellín (MDE)

B & H Airlines • Roundtrip • Coach
Price was $747, price is now $380 per person
$380
per person
found 1 day ago
Perfect location, excellent staff! Will definitely stay again here!

Reviewed on Sep 20, 2025

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More About Flying To Medellin from Cali

Route Information for Flights from Cali to Medellin

Origin Airport IATA Code
CLO
Destination Airport IATA Code
MDE
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

Cali to Medellin

Orbitz gives you great deals on your flights from Cali to Medellin. If you also need a discount car rental or a cheap hotel room after you arrived at your destination, Orbitz has you covered.

We Offer Great Travel Deals and Discounts

When you book flights from Cali to Medellin with Orbitz for, you can be assured that you are getting the lowest price possible. Orbitz works constantly with our airline partners to ensure guaranteed low prices on Cali to Medellin flights for your trip—whether you are traveling for business or for fun with your family.

Enjoy Savings on Last-Minute Flights

If you are looking for a discount price on last-minute flights from Cali to Medellin, chances are that Orbitz can offer you a deal that will save you lots of money. Whether you just want to get away for the weekend or go on a vacation lasting weeks, Orbitz can help you find the best deals on Cali to Medellin flights that fit your budget and your itinerary for the perfect trip.

Full-Service Mobile Apps

Need more mobility when it comes to travel planning? Orbitz has easy-to-use mobile apps for iPhone, iPad, and Android, to help the traveler on the go. Not only can use the apps to find huge savings on Cali to Medellin flights wherever you are, but you can also check out and book discount hotel rooms too. The apps will also keep you up-to-date when it’s time to fly. Get easy access to your itinerary for flights from Cali to Medellin and review gate and baggage claim details too.

Frequently asked questions

Are there non-stop flights from Cali to Medellin?
There are 3 airlines that offer nonstop services from Cali Airport to Medellin (MDE-Jose Maria Cordova Intl.), so get ready to hit that "book" button. One of these carriers will have the flight you're looking for:

  • LATAM Airlines
  • Viva Air Colombia
  • Avianca

What is the shortest flight from Cali to Medellin?
If the weather is good and all goes as scheduled, you could be coming in to land at Medellin (MDE-Jose Maria Cordova Intl.) from Alfonso Bonilla Aragon Intl. Airport (CLO) in only 49 minutes. With such a speedy flight time, contemplate taking hand luggage only.
What airlines fly from Cali to Medellin most frequently?
The airlines that fly frequently between Cali Airport and MDE include LATAM Airlines (LA). This well-known option offers 86 flights on the route each month. Viva Air Colombia (VH) will also take you to your destination in comfort. Offering 69 flights every month between Cali and Medellin, it's another popular airline to look into.
What is the cheapest day of the week to fly?
Consider flying out early in the week to save on your airfare. Orbitz data from 2021 shows that Monday is the cheapest day to depart, followed by Tuesday. Saturday showed the highest average ticket prices likely because many travelers prefer to start their vacation on a weekend.
What is the cheapest month to fly?
We won't keep you guessing, according to Orbitz data from 2021, the cheapest month to fly is February. Perfect for those who need a weekend getaway, or just a break from it all in the shortest month of the year. Be aware that the most expensive time to fly is during the height of summer in July, and in the holiday month of December.*According to flight demand on Orbitz.com from January to December 2021. Savings are subject to change based on departure location, date and destination.

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Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.