$109 Cheap flight deals from Tampa (TPA) to Grimes (DSM)
Earn rewards on top of your airline miles with Orbitz Rewards
Many airlines offer flexible change policies
Sign up to receive text alerts about your trip
Airfares from $109 One Way, $237 Round Trip from Tampa to Grimes
Prices starting at $237 for return flights and $109 for one-way flights to Grimes were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Grimes economy flight packages
Sonesta Simply Suites Des Moines
Aug 3 - Aug 6
Orlando (MCO) to Des Moines (DSM)
Des Moines (DSM) to Orlando (MCO)
Reviewed on Jun 30, 2026
Hotel Fort Des Moines, Curio Collection by Hilton
Aug 3 - Aug 6
Orlando (MCO) to Des Moines (DSM)
Des Moines (DSM) to Orlando (MCO)
Reviewed on Jun 30, 2026
Revel Hotel Des Moines Urbandale, Tapestry Collection by Hilton
Aug 3 - Aug 6
Orlando (MCO) to Des Moines (DSM)
Des Moines (DSM) to Orlando (MCO)
Reviewed on Jun 28, 2026
More About Flying To Grimes from Tampa
Route Information for Flights from Tampa to Grimes
Origin Airport IATA Code | TPA |
|---|---|
Destination Airport IATA Code | DSM |
Distance | |
Direct Flight Airlines | |
Earliest Flight Arrival | |
Latest Flight Arrival |
Tampa to Grimes
Orbitz combines guaranteed low prices with cutting-edge mobile tools for travel from Tampa to Grimes to give you a travel experience that is second to none.
Bargain Travel at Your Fingertips
Orbitz provides the cheapest fares from Tampa to Grimes. When reserving your flight you can mix and match a range of low cost airlines for you departing and returning domestic or international flights. This way you can travel on a budget while selecting the flights that suit your schedule.
Modern Tools for Fast-Paced Travel
Orbitz makes use of the latest technology to ensure that you are always kept up-to-date on the status of your Tampa to Grimes flights. Through easy-to-use mobile Android and iPhone apps you can book low cost flights from Tampa to Grimes and choose a range of cheap hotels to stay in.
Enjoy Stress-Free Travel with Flight Alerts
Once you have booked your flights from Tampa to Grimes on Orbitz you will always be kept informed of any changes to your flight. When you opt into Orbitz’s free email and SMS alerts on your Tampa to Grimes flights you can ask Orbitz to send the flight details to up to 6 other contacts, so keeping your family and business team informed is a cinch.
Frequent Flyer Program
For loyal Orbitz customers who fly from Tampa to Grimes the chance to join our frequent flyer program is an added bonus. Simply log-on to your online account and input your frequent flyer number for future flights.
Flights from Tampa
- Tampa to New York
- Tampa to Atlanta
- Tampa to Chicago
- Tampa to London
- Tampa to Phoenix
- Tampa to Toronto
- Tampa to Dallas
- Tampa to Houston
- Tampa to Rome
- Tampa to Detroit
- Tampa to Washington
- Tampa to Los Angeles
- Tampa to Charlotte
- Tampa to New Orleans
- Tampa to San Francisco
- Tampa to Columbus
- Tampa to Paris
- Tampa to Montreal
- Tampa to Kansas City
- Tampa to Orlando
Grimes Airports
More Destinations
- Flights from Alexandria to Clive
- Flights from Baltimore to Clive
- Flights from Calgary to Clive
- Flights from Chicago to Clive
- Flights from Cleveland to Clive
- Flights from Dallas to Clive
- Flights from Detroit to Clive
- Flights from Houston to Clive
- Flights from Las Vegas to Clive
- Flights from New York to Clive
- Flights from Phoenix to Clive
- Flights from Salt Lake City to Clive
- Flights from Seattle to Clive
- Flights from Toronto to Clive
- Flights from Washington to Clive
- Flights from Paris to Clive
- Flights from Edmonton to Clive
- Flights from Jackson to Clive
- Flights from Accra to Clive
- Flights from Newark to Clive
- Flights from Richmond to Clive
- Flights from Albuquerque to Clive
- Flights from Akron to Clive
- Flights from Tampa to Clive
- Flights from Wichita to Clive
- Flights from Whitefish to Urbandale
- Flights from Houston to Urbandale
- Flights from Salt Lake City to Urbandale
- Flights from Covington to Urbandale
- Flights from Bozeman to Urbandale
- Flights from Duluth to West Des Moines
- Flights from Helena to West Des Moines
- Flights from Baltimore to West Des Moines
- Flights from Calgary to West Des Moines
- Flights from Lima to West Des Moines
- Flights from Philadelphia to West Des Moines
- Flights from St. Petersburg to West Des Moines
- Flights from Missoula to West Des Moines
- Flights from Newark to West Des Moines
- Flights from Madison to West Des Moines
- Flights from Asheville to West Des Moines
- Flights from Rock Springs to West Des Moines
- Flights from Fort Smith to West Des Moines
- Flights from Covington to West Des Moines
- Flights from Grand Canyon to West Des Moines
- Flights from Baltimore to Des Moines
- Flights from Cincinnati to Des Moines
- Flights from Cleveland to Des Moines
- Flights from Columbus to Des Moines
- Flights from Memphis to Des Moines
- Flights from New Orleans to Des Moines
- Flights from Philadelphia to Des Moines
- Flights from San Antonio to Des Moines
- Flights from San Francisco to Des Moines
- Flights from Toronto to Des Moines
- Flights from Washington to Des Moines
- Flights from Hartford to Des Moines
- Flights from Sacramento to Des Moines
- Flights from Mason City to Des Moines
- Flights from Pittsburgh to Des Moines
- Flights from Fort Lauderdale to Des Moines
- Flights from Newark to Des Moines
- Flights from Richmond to Des Moines
- Flights from Syracuse to Des Moines
- Flights from Tulsa to Des Moines
- Flights from Pensacola to Des Moines
- Flights from Buffalo to Des Moines
- Flights from Little Rock to Des Moines
- Flights from Springfield to Des Moines
- Flights from Rochester to Des Moines
- Flights from Oklahoma City to Des Moines
- Flights from Knoxville to Des Moines
- Flights from Tucson to Des Moines
- Flights from Colorado Springs to Des Moines
- Flights from Jacksonville to Des Moines
- Flights from Boise to Des Moines
- Flights from Louisville to Des Moines
- Flights from Grand Rapids to Des Moines
- Flights from Rapid City to Des Moines
- Flights from Anchorage to Ankeny
- Flights from Beijing to Ankeny
- Flights from Charlotte to Ankeny
- Flights from Los Angeles to Ankeny
- Flights from Portland to Ankeny
- Flights from Cancun to Ankeny
- Flights from Durango to Ankeny
- Flights from Hilton Head Island to Ankeny
- Flights from Burlington to Ankeny
- Flights from Syracuse to Ankeny
- Flights from Daytona Beach to Ankeny
- Flights from Buffalo to Ankeny
- Flights from Reno to Ankeny
- Flights from Madison to Ankeny
- Flights from Little Rock to Ankeny
- Flights from Jacksonville to Ankeny
- Flights from Lexington to Ankeny
- Flights from Grand Rapids to Ankeny
- Flights from Greenville - Spartanburg to Ankeny
- Flights from Dubai to Ankeny
- Flights from Walla Walla to Ankeny
Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.