$132 Cheap flight deals from Tampa (TPA) to Grimes (DSM)
Earn rewards on top of your airline miles with Orbitz Rewards
Many airlines offer flexible change policies
Sign up to receive text alerts about your trip
This Weekend's Flight Deals from Tampa to Grimes
This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Airfares from $132 One Way, $267 Round Trip from Tampa to Grimes
Prices starting at $267 for return flights and $132 for one-way flights to Grimes were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Grimes economy flight packages
AmericInn by Wyndham Des Moines Airport
Nov 25 - Nov 28
Tampa (TPA) to Des Moines (DSM)
Reviewed on Aug 13, 2025
La Quinta by Wyndham Altoona Des Moines
Nov 25 - Nov 28
Tampa (TPA) to Des Moines (DSM)
Reviewed on Sep 3, 2025
Residence Inn Des Moines Downtown
Nov 25 - Nov 28
Tampa (TPA) to Des Moines (DSM)
Reviewed on Mar 24, 2025
More About Flying To Grimes from Tampa
Route Information for Flights from Tampa to Grimes
Origin Airport IATA Code | TPA |
|---|---|
Destination Airport IATA Code | DSM |
Distance | |
Direct Flight Airlines | |
Earliest Flight Arrival | |
Latest Flight Arrival |
Tampa to Grimes
Grab great fares on Tampa to Grimes flights with Orbitz, your #1 source for discount international and domestic air tickets. Our cutting-edge mobile tools and great online search functionality make booking your next budget trip a breeze.
Mobile Apps for Exclusive Deals on Flights From Tampa to Grimes
You don’t have to sit down at a computer to find the latest flight bargains. Orbitz offers a mobile app for Android, iPhone, and tablet devices, which will keep you alert to fantastic fares, hotel discounts, and more great savings. The app gives you real-time low fares for flights from Tampa to Grimes and lets you book your hotel room with a few simple clicks.
Find Your Tampa to Grimes Flights, Car, and Hotel in One Place
Orbitz gives you the latest deals on air fares, hotels, cruises, and car rentals at up to 50% off. Booking your flights from Tampa to Grimes is easy whether you are using a computer, with the Orbitz mobile app, or through m.orbitz.com on your mobile device’s Web browser.
Stay Informed on Your Trip
Orbitz sends you alerts about the latest updates to your Tampa to Grimes flights, such as delays. Receive the updates via your email or mobile phone. Use the Orbitz app to stay updated on your flight status and baggage claim details.
Earn Miles for Flights From Tampa to Grimes
On qualified flights, add your frequent flyer number to your booking to get miles or points for your trip.
Flights from Tampa
- Tampa to New York
- Tampa to Atlanta
- Tampa to Chicago
- Tampa to Toronto
- Tampa to London
- Tampa to Dallas
- Tampa to Phoenix
- Tampa to Detroit
- Tampa to Los Angeles
- Tampa to Houston
- Tampa to San Francisco
- Tampa to Washington
- Tampa to Charlotte
- Tampa to Rome
- Tampa to New Orleans
- Tampa to Columbus
- Tampa to Paris
- Tampa to Orlando
- Tampa to Montreal
- Tampa to Kansas City
Grimes Airports
More Destinations
More Destinations
- Flights from Alexandria to Clive
- Flights from Baltimore to Clive
- Flights from Calgary to Clive
- Flights from Chicago to Clive
- Flights from Cleveland to Clive
- Flights from Dallas to Clive
- Flights from Detroit to Clive
- Flights from Houston to Clive
- Flights from Las Vegas to Clive
- Flights from New York to Clive
- Flights from Phoenix to Clive
- Flights from Salt Lake City to Clive
- Flights from Seattle to Clive
- Flights from Toronto to Clive
- Flights from Washington to Clive
- Flights from Paris to Clive
- Flights from Edmonton to Clive
- Flights from Jackson to Clive
- Flights from Accra to Clive
- Flights from Newark to Clive
- Flights from Richmond to Clive
- Flights from Albuquerque to Clive
- Flights from Akron to Clive
- Flights from Tampa to Clive
- Flights from Wichita to Clive
- Flights from Whitefish to Urbandale
- Flights from Houston to Urbandale
- Flights from Salt Lake City to Urbandale
- Flights from Covington to Urbandale
- Flights from Bozeman to Urbandale
- Flights from Duluth to West Des Moines
- Flights from Helena to West Des Moines
- Flights from Baltimore to West Des Moines
- Flights from Calgary to West Des Moines
- Flights from Lima to West Des Moines
- Flights from Philadelphia to West Des Moines
- Flights from St. Petersburg to West Des Moines
- Flights from Missoula to West Des Moines
- Flights from Newark to West Des Moines
- Flights from Madison to West Des Moines
- Flights from Asheville to West Des Moines
- Flights from Rock Springs to West Des Moines
- Flights from Fort Smith to West Des Moines
- Flights from Covington to West Des Moines
- Flights from Grand Canyon to West Des Moines
- Flights from Baltimore to Des Moines
- Flights from Cincinnati to Des Moines
- Flights from Cleveland to Des Moines
- Flights from Columbus to Des Moines
- Flights from Memphis to Des Moines
- Flights from New Orleans to Des Moines
- Flights from Philadelphia to Des Moines
- Flights from San Antonio to Des Moines
- Flights from San Francisco to Des Moines
- Flights from Toronto to Des Moines
- Flights from Washington to Des Moines
- Flights from Hartford to Des Moines
- Flights from Sacramento to Des Moines
- Flights from Mason City to Des Moines
- Flights from Pittsburgh to Des Moines
- Flights from Fort Lauderdale to Des Moines
- Flights from Newark to Des Moines
- Flights from Richmond to Des Moines
- Flights from Syracuse to Des Moines
- Flights from Tulsa to Des Moines
- Flights from Pensacola to Des Moines
- Flights from Buffalo to Des Moines
- Flights from Little Rock to Des Moines
- Flights from Springfield to Des Moines
- Flights from Rochester to Des Moines
- Flights from Oklahoma City to Des Moines
- Flights from Knoxville to Des Moines
- Flights from Tucson to Des Moines
- Flights from Colorado Springs to Des Moines
- Flights from Jacksonville to Des Moines
- Flights from Boise to Des Moines
- Flights from Louisville to Des Moines
- Flights from Grand Rapids to Des Moines
- Flights from Rapid City to Des Moines
- Flights from Anchorage to Ankeny
- Flights from Beijing to Ankeny
- Flights from Charlotte to Ankeny
- Flights from Los Angeles to Ankeny
- Flights from Portland to Ankeny
- Flights from Cancun to Ankeny
- Flights from Durango to Ankeny
- Flights from Hilton Head Island to Ankeny
- Flights from Burlington to Ankeny
- Flights from Syracuse to Ankeny
- Flights from Daytona Beach to Ankeny
- Flights from Buffalo to Ankeny
- Flights from Reno to Ankeny
- Flights from Madison to Ankeny
- Flights from Little Rock to Ankeny
- Flights from Jacksonville to Ankeny
- Flights from Lexington to Ankeny
- Flights from Grand Rapids to Ankeny
- Flights from Greenville - Spartanburg to Ankeny
- Flights from Dubai to Ankeny
- Flights from Walla Walla to Ankeny
Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.