$181 Cheap flight deals from Buffalo (BUF) to Santo Domingo (SDQ)

Airfares from $181 One Way, $391 Round Trip from Buffalo to Santo Domingo

Prices starting at $391 for return flights and $181 for one-way flights to Santo Domingo were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sun, Sep 13 - Sat, Sep 19
BUF
Buffalo
SDQ
Santo Domingo
$391 Roundtrip, found 5 days ago
$391
Roundtrip
found 5 days ago
Select American Airlines flight, departing Sun, Sep 13 from Buffalo to Santo Domingo, returning Sat, Sep 19, priced at $391 found 5 days ago
Sun, Sep 13 - Sat, Sep 19
BUF
Buffalo
SDQ
Santo Domingo
$413 Roundtrip, found 5 days ago
$413
Roundtrip
found 5 days ago
Select American Airlines flight, departing Sun, Sep 13 from Buffalo to Santo Domingo, returning Sat, Sep 19, priced at $413 found 5 days ago
Thu, Jul 9 - Mon, Jul 13
BUF
Buffalo
SDQ
Santo Domingo
$433 Roundtrip, found 6 days ago
$433
Roundtrip
found 6 days ago
Select American Airlines flight, departing Thu, Jul 9 from Buffalo to Santo Domingo, returning Mon, Jul 13, priced at $433 found 6 days ago
Sun, Sep 13 - Sat, Sep 19
BUF
Buffalo
SDQ
Santo Domingo
$448 Roundtrip, found 5 days ago
$448
Roundtrip
found 5 days ago
Select American Airlines flight, departing Sun, Sep 13 from Buffalo to Santo Domingo, returning Sat, Sep 19, priced at $448 found 5 days ago
Sun, Sep 13 - Sat, Sep 19
BUF
Buffalo
SDQ
Santo Domingo
$461 Roundtrip, found 5 days ago
$461
Roundtrip
found 5 days ago
Select American Airlines flight, departing Sun, Sep 13 from Buffalo to Santo Domingo, returning Sat, Sep 19, priced at $461 found 5 days ago

Santo Domingo economy flight packages

Price found within the past 48 hours. Click for updated prices.
Bahia Principe Escape Bouganville - Adults Only - All Inclusive
4.5-star property

Bahia Principe Escape Bouganville - Adults Only - All Inclusive

8.8/10 Excellent! (2,702 reviews)

Jun 12 - Jun 16

4 night stay

Buffalo (BUF) to Santo Domingo (SDQ)

JetBlue Airways • Non-stop • Coach

Santo Domingo (SDQ) to Buffalo (BUF)

American Airlines • Non-stop • Coach
Price was $1,456, price is now $976 per person
$976
per person
found 1 day ago
Great place, great people.

Reviewed on May 4, 2026

Coral Costa Caribe Beach Resort - All Inclusive
4.0-star property

Coral Costa Caribe Beach Resort - All Inclusive

7.8/10 Good! (2,560 reviews)

Jun 12 - Jun 19

7 night stay

Buffalo (BUF) to Santo Domingo (SDQ)

JetBlue Airways • Non-stop • Coach

Santo Domingo (SDQ) to Buffalo (BUF)

American Airlines • Non-stop • Coach
Price was $2,358, price is now $1,058 per person
$1,058
per person
found 5 hours ago
Place and staff was awesome would def be bk Food was great

Reviewed on Oct 14, 2025

Bahia Principe Escape Samaná - Adults Only
4.5-star property

Bahia Principe Escape Samaná - Adults Only

8.8/10 Excellent! (675 reviews)

Jun 26 - Jul 3

7 night stay

Buffalo (BUF) to Santo Domingo (SDQ)

American Airlines • Non-stop roundtrip • Coach
Save 100% on your flight
Price was $2,065, price is now $1,307 per person
$1,307
per person
found 12 hours ago
Beautiful hotel, friendly staff, Room had an amazing view of the ocean. The food was far better then expected and alcohol selection was also good. My overall stay was amazing, got the rest i needed. I would definitely recommend the resort to anyone.

Reviewed on Dec 18, 2018

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