$146 Cheap flight deals from Buffalo (BUF) to Santo Domingo (SDQ)

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This Weekend's Flight Deals from Buffalo to Santo Domingo

This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sun, Feb 15 - Wed, Feb 18
BUF
Buffalo Niagara Intl.
SDQ
Las Americas Intl.
$426 Roundtrip, found 5 days ago
$426
Roundtrip
found 5 days ago
Select JetBlue Airways flight, departing Sun, Feb 15 from Buffalo Niagara Intl. to Las Americas Intl., returning Wed, Feb 18, priced at $426 found 5 days ago

Airfares from $146 One Way, $319 Round Trip from Buffalo to Santo Domingo

Prices starting at $319 for return flights and $146 for one-way flights to Santo Domingo were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Mon, Mar 2 - Thu, Mar 5
BUF
Buffalo
SDQ
Santo Domingo
$319 Roundtrip, found 8 hours ago
$319
Roundtrip
found 8 hours ago
Select American Airlines flight, departing Mon, Mar 2 from Buffalo to Santo Domingo, returning Thu, Mar 5, priced at $319 found 8 hours ago
Mon, Apr 13 - Sat, Apr 18
BUF
Buffalo
SDQ
Santo Domingo
$331 Roundtrip, found 2 days ago
$331
Roundtrip
found 2 days ago
Select JetBlue Airways flight, departing Mon, Apr 13 from Buffalo to Santo Domingo, returning Sat, Apr 18, priced at $331 found 2 days ago
Mon, Mar 2 - Thu, Mar 5
BUF
Buffalo
SDQ
Santo Domingo
$335 Roundtrip, found 8 hours ago
$335
Roundtrip
found 8 hours ago
Select American Airlines flight, departing Mon, Mar 2 from Buffalo to Santo Domingo, returning Thu, Mar 5, priced at $335 found 8 hours ago
Mon, Mar 2 - Thu, Mar 5
BUF
Buffalo
SDQ
Santo Domingo
$341 Roundtrip, found 8 hours ago
$341
Roundtrip
found 8 hours ago
Select American Airlines flight, departing Mon, Mar 2 from Buffalo to Santo Domingo, returning Thu, Mar 5, priced at $341 found 8 hours ago
Mon, Mar 2 - Thu, Mar 5
BUF
Buffalo
SDQ
Santo Domingo
$342 Roundtrip, found 8 hours ago
$342
Roundtrip
found 8 hours ago
Select Delta flight, departing Mon, Mar 2 from Buffalo to Santo Domingo, returning Thu, Mar 5, priced at $342 found 8 hours ago

Santo Domingo economy flight packages

Price found within the past 48 hours. Click for updated prices.
Bahia Principe Grand La Romana - All Inclusive
4.5-star property

Bahia Principe Grand La Romana - All Inclusive

8.4/10 Very Good! (2,634 reviews)

Mar 28 - Apr 3

6 night stay

Buffalo (BUF) to Santo Domingo (SDQ)

JetBlue Airways • Non-stop roundtrip • Coach
Save 100% on your flight
Price was $2,718, price is now $1,830 per person
$1,830
per person
found 1 day ago
Breakfast, lunch, dinner snacks was fresh & well maintained cleanliness & staffs are very nice & helpful! Excellent entertainment. Love our stay & had a wonderful family vacation.

Reviewed on Dec 27, 2025

Bahia Principe Luxury Bouganville - Adults Only - All Inclusive
4.5-star property

Bahia Principe Luxury Bouganville - Adults Only - All Inclusive

8.8/10 Excellent! (2,770 reviews)

Mar 28 - Apr 3

6 night stay

Buffalo (BUF) to Santo Domingo (SDQ)

JetBlue Airways • Non-stop roundtrip • Coach
Save 100% on your flight
Price was $2,870, price is now $1,910 per person
$1,910
per person
found 1 day ago
Luxury is definitely a good way to describe. Was more than expected when considering the price! Excellent deal. Staff went above and beyond and food exquisite. Maria and Enervira are two on a long list that created fantastico memories ... The landscape plants and statues such a beautiful place

Reviewed on Oct 20, 2025

Bahia Principe Grand Samana - Adults Only
4.5-star property

Bahia Principe Grand Samana - Adults Only

8.8/10 Excellent! (624 reviews)

Mar 28 - Apr 3

6 night stay

Buffalo (BUF) to Santo Domingo (SDQ)

JetBlue Airways • Non-stop roundtrip • Coach
Save 100% on your flight
Price was $2,722, price is now $1,844 per person
$1,844
per person
found 1 day ago
Beautiful hotel, friendly staff, Room had an amazing view of the ocean. The food was far better then expected and alcohol selection was also good. My overall stay was amazing, got the rest i needed. I would definitely recommend the resort to anyone.

Reviewed on Dec 18, 2018

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More About Flying To Santo Domingo from Buffalo

Route Information for Flights from Buffalo to Santo Domingo

Origin Airport IATA Code
BUF
Destination Airport IATA Code
SDQ
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

Buffalo to Santo Domingo

Orbitz can provide you with the greatest deals on a wide range of Buffalo to Santo Domingo flights. Orbitz offers guaranteed low prices and offers you the convenience of cutting-edge mobile tools thus providing you with your best travel experience ever.

Mobile Apps for Buffalo to Santo Domingo Flights

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Loyalty Rewarded

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 Budget Flying Made Simple

Finding cheap flights from Buffalo to Santo Domingo is easy with Orbitz. You can pick and choose airlines for your international flights to create inexpensive yet convenient travel arrangements.

Frequently asked questions

What is the shortest flight from Buffalo to Santo Domingo?
With the journey from Buffalo Niagara Intl. Airport (BUF) to Santo Domingo Airport taking a minimum of 4 hours and 58 minutes, there's plenty of time to kick back and enjoy the ride. Treat yourself to a glass of red and get comfy in your seat with an interesting book or movie.
What is the cheapest day of the week to fly?
Consider flying out early in the week to save on your airfare. Orbitz data from 2021 shows that Monday is the cheapest day to depart, followed by Tuesday. Saturday showed the highest average ticket prices likely because many travelers prefer to start their vacation on a weekend.
What is the cheapest month to fly?
We won't keep you guessing, according to Orbitz data from 2021, the cheapest month to fly is February. Perfect for those who need a weekend getaway, or just a break from it all in the shortest month of the year. Be aware that the most expensive time to fly is during the height of summer in July, and in the holiday month of December.*According to flight demand on Orbitz.com from January to December 2021. Savings are subject to change based on departure location, date and destination.

More Destinations

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.