$145 Cheap flight deals from Buffalo (BUF) to Santo Domingo (SDQ)

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This Weekend's Flight Deals from Buffalo to Santo Domingo

This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sat, Dec 27 - Mon, Dec 29
BUF
Buffalo Niagara Intl.
SDQ
Las Americas Intl.
$512 Roundtrip, found 1 day ago
$512
Roundtrip
found 1 day ago
Select American Airlines flight, departing Sat, Dec 27 from Buffalo Niagara Intl. to Las Americas Intl., returning Mon, Dec 29, priced at $512 found 1 day ago

Airfares from $145 One Way, $318 Round Trip from Buffalo to Santo Domingo

Prices starting at $318 for return flights and $145 for one-way flights to Santo Domingo were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Thu, Feb 19 - Wed, Feb 25
BUF
Buffalo
SDQ
Santo Domingo
$318 Roundtrip, found 2 days ago
$318
Roundtrip
found 2 days ago
Select American Airlines flight, departing Thu, Feb 19 from Buffalo to Santo Domingo, returning Wed, Feb 25, priced at $318 found 2 days ago
Sat, Mar 14 - Fri, Mar 20
BUF
Buffalo
SDQ
Santo Domingo
$324 Roundtrip, found 1 day ago
$324
Roundtrip
found 1 day ago
Select American Airlines flight, departing Sat, Mar 14 from Buffalo to Santo Domingo, returning Fri, Mar 20, priced at $324 found 1 day ago
Wed, Mar 11 - Wed, Mar 25
BUF
Buffalo
SDQ
Santo Domingo
$328 Roundtrip, found 2 hours ago
$328
Roundtrip
found 2 hours ago
Select Delta flight, departing Wed, Mar 11 from Buffalo to Santo Domingo, returning Wed, Mar 25, priced at $328 found 2 hours ago
Mon, Mar 2 - Wed, Mar 18
BUF
Buffalo
SDQ
Santo Domingo
$329 Roundtrip, found 2 hours ago
$329
Roundtrip
found 2 hours ago
Select Delta flight, departing Mon, Mar 2 from Buffalo to Santo Domingo, returning Wed, Mar 18, priced at $329 found 2 hours ago
Mon, Apr 13 - Sat, May 2
BUF
Buffalo
SDQ
Santo Domingo
$330 Roundtrip, found 2 hours ago
$330
Roundtrip
found 2 hours ago
Select JetBlue Airways flight, departing Mon, Apr 13 from Buffalo to Santo Domingo, returning Sat, May 2, priced at $330 found 2 hours ago

Santo Domingo economy flight packages

Price found within the past 48 hours. Click for updated prices.
Bahia Principe Grand La Romana - All Inclusive
4.5-star property

Bahia Principe Grand La Romana - All Inclusive

8.4/10 Very Good! (2,634 reviews)

Feb 4 - Feb 10

6 night stay

Buffalo (BUF) to Santo Domingo (SDQ)

American Airlines • Roundtrip • Coach
Save 100% on your flight
Price was $2,152, price is now $1,227 per person
$1,227
per person
found 1 day ago
The food eas horrible sometimes, salty and no taste

Reviewed on Nov 15, 2025

Bahia Principe Luxury Bouganville - Adults Only - All Inclusive
4.5-star property

Bahia Principe Luxury Bouganville - Adults Only - All Inclusive

8.8/10 Excellent! (2,770 reviews)

Feb 4 - Feb 10

6 night stay

Buffalo (BUF) to Santo Domingo (SDQ)

Delta • Non-stop • Coach

Santo Domingo (SDQ) to Buffalo (BUF)

American Airlines • Non-stop • Coach
Save 100% on your flight
Price was $2,347, price is now $1,294 per person
$1,294
per person
found 1 day ago
Luxury is definitely a good way to describe. Was more than expected when considering the price! Excellent deal. Staff went above and beyond and food exquisite. Maria and Enervira are two on a long list that created fantastico memories ... The landscape plants and statues such a beautiful place

Reviewed on Oct 20, 2025

Bahia Principe Grand Samana - Adults Only
4.5-star property

Bahia Principe Grand Samana - Adults Only

8.8/10 Excellent! (624 reviews)

Jan 28 - Feb 3

6 night stay

Buffalo (BUF) to Santo Domingo (SDQ)

Delta • Non-stop • Coach

Santo Domingo (SDQ) to Buffalo (BUF)

American Airlines • Non-stop • Coach
Save 100% on your flight
Price was $2,195, price is now $1,230 per person
$1,230
per person
found 1 day ago
Beautiful hotel, friendly staff, Room had an amazing view of the ocean. The food was far better then expected and alcohol selection was also good. My overall stay was amazing, got the rest i needed. I would definitely recommend the resort to anyone.

Reviewed on Dec 18, 2018

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More About Flying To Santo Domingo from Buffalo

Route Information for Flights from Buffalo to Santo Domingo

Origin Airport IATA Code
BUF
Destination Airport IATA Code
SDQ
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

Buffalo to Santo Domingo

Orbitz is the best place to find guaranteed low prices on Buffalo to Santo Domingo flights. Because of our cutting-edge mobile tools and low fares on domestic and international flights, Orbitz is the best starting point for travelers.

Find Cheap Buffalo to Santo Domingo Flights

Orbitz offers free mobile apps for iPhone and Android devices—a great way to find fantastic deals on flights from Buffalo to Santo Domingo. Not only that, but you can check the status of your flight or even book low cost hotel rooms with the apps or on m.orbitz.com.

Get Miles and Points for Your Flight

Simply enter your frequent flyer information while booking to get miles or points for qualifying Buffalo to Santo Domingo flights. This information can all be saved in your Orbitz account, which means it will not have to be entered each time you take advantage of a great air fare deal.

Flight Alerts Take Away the Stress

Orbitz does not want travelers to worry on their flights from Buffalo to Santo Domingo. We keep you updated on any flight changes for Buffalo to Santo Domingo flights with alerts sent directly to your email or a mobile device. These alerts can also be sent to friends and family.

Discount Travel Planning Made Simple

You will have no problems finding budget flights from Buffalo to Santo Domingo on Orbitz.com. If your travel plans are flexible, you can search for fares three days before and after a specific date to find the best price.

Frequently asked questions

What is the shortest flight from Buffalo to Santo Domingo?
With the journey from Buffalo Niagara Intl. Airport (BUF) to Santo Domingo Airport taking a minimum of 4 hours and 58 minutes, there's plenty of time to kick back and enjoy the ride. Treat yourself to a glass of red and get comfy in your seat with an interesting book or movie.
What is the cheapest day of the week to fly?
Consider flying out early in the week to save on your airfare. Orbitz data from 2021 shows that Monday is the cheapest day to depart, followed by Tuesday. Saturday showed the highest average ticket prices likely because many travelers prefer to start their vacation on a weekend.
What is the cheapest month to fly?
We won't keep you guessing, according to Orbitz data from 2021, the cheapest month to fly is February. Perfect for those who need a weekend getaway, or just a break from it all in the shortest month of the year. Be aware that the most expensive time to fly is during the height of summer in July, and in the holiday month of December.*According to flight demand on Orbitz.com from January to December 2021. Savings are subject to change based on departure location, date and destination.

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Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.