$150 Cheap flight deals from Buffalo (BUF) to Santo Domingo (SDQ)

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This Weekend's Flight Deals from Buffalo to Santo Domingo

This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sun, Nov 16 - Fri, Nov 21
BUF
Buffalo Niagara Intl.
SDQ
Las Americas Intl.
$328 Roundtrip, found 6 days ago
$328
Roundtrip
found 6 days ago
Select American Airlines flight, departing Sun, Nov 16 from Buffalo Niagara Intl. to Las Americas Intl., returning Fri, Nov 21, priced at $328 found 6 days ago

Airfares from $150 One Way, $326 Round Trip from Buffalo to Santo Domingo

Prices starting at $326 for return flights and $150 for one-way flights to Santo Domingo were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Tue, Nov 18 - Tue, Nov 25
BUF
Buffalo
SDQ
Santo Domingo
$326 Roundtrip, found 2 days ago
$326
Roundtrip
found 2 days ago
Select JetBlue Airways flight, departing Tue, Nov 18 from Buffalo to Santo Domingo, returning Tue, Nov 25, priced at $326 found 2 days ago
Sun, Nov 16 - Fri, Nov 21
BUF
Buffalo
SDQ
Santo Domingo
$328 Roundtrip, found 6 days ago
$328
Roundtrip
found 6 days ago
Select American Airlines flight, departing Sun, Nov 16 from Buffalo to Santo Domingo, returning Fri, Nov 21, priced at $328 found 6 days ago
Sun, Jan 25 - Sun, Feb 8
BUF
Buffalo
SDQ
Santo Domingo
$342 Roundtrip, found 10 hours ago
$342
Roundtrip
found 10 hours ago
Select Delta flight, departing Sun, Jan 25 from Buffalo to Santo Domingo, returning Sun, Feb 8, priced at $342 found 10 hours ago
Sun, Nov 16 - Fri, Nov 21
BUF
Buffalo
SDQ
Santo Domingo
$346 Roundtrip, found 6 days ago
$346
Roundtrip
found 6 days ago
Select American Airlines flight, departing Sun, Nov 16 from Buffalo to Santo Domingo, returning Fri, Nov 21, priced at $346 found 6 days ago
Sun, Jan 25 - Sun, Feb 8
BUF
Buffalo
SDQ
Santo Domingo
$346 Roundtrip, found 10 hours ago
$346
Roundtrip
found 10 hours ago
Select Delta flight, departing Sun, Jan 25 from Buffalo to Santo Domingo, returning Sun, Feb 8, priced at $346 found 10 hours ago

Santo Domingo economy flight packages

Price found within the past 48 hours. Click for updated prices.
Bahia Principe Grand La Romana - All Inclusive
4.5-star property

Bahia Principe Grand La Romana - All Inclusive

8.4/10 Very Good! (2,620 reviews)

Dec 22 - Dec 27

5 night stay

Buffalo (BUF) to Santo Domingo (SDQ)

JetBlue Airways • Non-stop • Coach

Santo Domingo (SDQ) to Buffalo (BUF)

American Airlines • Non-stop • Coach
Save 100% on your flight
Price was $2,481, price is now $1,559 per person
$1,559
per person
found 1 day ago
The property is beautiful and very well kept. Easy to maneuver around from start to finish. The check in process was fast and everyone at the counter was super nice and helpful. The carts that help with luggage, moved efficiently and quickly getting everyone settled. Rooms were clean, stocked, and the temperature was nice and cool. The food was great and had a big variety. The staff at the main food area was always so nice and went above and beyond no matter how busy they were. Lala was amazing and always had a smile on her face. From what I saw, she was like that with everyone. Whatever she gets paid, its not enough on how that woman is always on the go. There was always something to do at the resort. The animation group was amazing in keeping everyone entertained. You can tell that they truly love their jobs because they gave it their all...EVERYDAY. We scheduled a tour and that was extremely fun. The man that schedules you was friendly and helpful as well. I went this time with no kids and saw how much the kids there had fun. I would absolutely love to repeat my visit with my children here.

Reviewed on Aug 13, 2025

Eurostars Grand Cayacoa
4.5-star property

Eurostars Grand Cayacoa

8.2/10 Very Good! (569 reviews)

Dec 19 - Dec 27

8 night stay

Buffalo (BUF) to Santo Domingo (SDQ)

Delta • Non-stop • Coach

Santo Domingo (SDQ) to Buffalo (BUF)

American Airlines • Non-stop • Coach
Save 100% on your flight
Price was $2,673, price is now $1,616 per person
$1,616
per person
found 17 hours ago
Beautiful people, awesome place and service! Very much pleased 😀

Reviewed on Jan 29, 2024

Bahia Principe Luxury Bouganville - Adults Only - All Inclusive
4.5-star property

Bahia Principe Luxury Bouganville - Adults Only - All Inclusive

8.8/10 Excellent! (2,802 reviews)

Dec 22 - Dec 27

5 night stay

Buffalo (BUF) to Santo Domingo (SDQ)

JetBlue Airways • Non-stop • Coach

Santo Domingo (SDQ) to Buffalo (BUF)

American Airlines • Non-stop • Coach
Save 100% on your flight
Price was $2,780, price is now $1,702 per person
$1,702
per person
found 1 day ago
Luxury is definitely a good way to describe. Was more than expected when considering the price! Excellent deal. Staff went above and beyond and food exquisite. Maria and Enervira are two on a long list that created fantastico memories ... The landscape plants and statues such a beautiful place

Reviewed on Oct 20, 2025

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More About Flying To Santo Domingo from Buffalo

Route Information for Flights from Buffalo to Santo Domingo

Origin Airport IATA Code
BUF
Destination Airport IATA Code
SDQ
Distance
Direct Flight Airlines
Earliest Flight Arrival
Latest Flight Arrival

Buffalo to Santo Domingo

Orbitz has your discount air ticket deals for flights from Buffalo to Santo Domingo. The guaranteed low prices from flights and hotels to car rentals and vacation packages make Orbitz the perfect travel website for budget trip planning.

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While Orbitz gives you access to cheap tickets for Buffalo to Santo Domingo flights, the travel site also offers free email, voice, or text message alerts to keep you informed of any abrupt changes or delays that affect your travel. You can even choose to have the alerts sent to up to six of your mobile or email contacts to keep your friends in the loop.

Bargain Buffalo to Santo Domingo Flights With Mobile Apps

Download the cutting-edge Orbitz app for either Android or iPhone, and use it to check on the status of your upcoming flights from Buffalo to Santo Domingo at any time. These apps also make it easy for you to book discount hotel rates in your destination city and check for deals on future Buffalo to Santo Domingo flights.

Frequently asked questions

What is the shortest flight from Buffalo to Santo Domingo?
With the journey from Buffalo Niagara Intl. Airport (BUF) to Santo Domingo Airport taking a minimum of 4 hours and 58 minutes, there's plenty of time to kick back and enjoy the ride. Treat yourself to a glass of red and get comfy in your seat with an interesting book or movie.
What is the cheapest day of the week to fly?
Consider flying out early in the week to save on your airfare. Orbitz data from 2021 shows that Monday is the cheapest day to depart, followed by Tuesday. Saturday showed the highest average ticket prices likely because many travelers prefer to start their vacation on a weekend.
What is the cheapest month to fly?
We won't keep you guessing, according to Orbitz data from 2021, the cheapest month to fly is February. Perfect for those who need a weekend getaway, or just a break from it all in the shortest month of the year. Be aware that the most expensive time to fly is during the height of summer in July, and in the holiday month of December.*According to flight demand on Orbitz.com from January to December 2021. Savings are subject to change based on departure location, date and destination.

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Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.