
$98 Cheap flight deals from Des Moines (DSM) to Santa Clarita (BUR)
Earn rewards on top of your airline miles with Orbitz Rewards
Many airlines offer flexible change policies
Sign up to receive text alerts about your trip
This Weekend's Flight Deals from Des Moines to Santa Clarita
This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Airfares from $98 One Way, $164 Round Trip from Des Moines to Santa Clarita
Prices starting at $164 for return flights and $98 for one-way flights to Santa Clarita were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Santa Clarita economy flight packages

Anaheim Discovery Inn & Suites
Feb 27 - Mar 2
Des Moines (DSM) to Los Angeles (LAX)
Los Angeles (LAX) to Des Moines (DSM)
Reviewed on Aug 3, 2025

W Los Angeles - West Beverly Hills
Feb 27 - Mar 2
Des Moines (DSM) to Los Angeles (LAX)
Reviewed on Jul 29, 2025

Fairmont Miramar Bungalows
Feb 27 - Mar 2
Des Moines (DSM) to Los Angeles (LAX)
Reviewed on Mar 5, 2022
More About Flying To Santa Clarita from Des Moines
Route Information for Flights from Des Moines to Santa Clarita
Origin Airport IATA Code | DSM |
|---|---|
Destination Airport IATA Code | BUR |
Distance | |
Direct Flight Airlines | |
Earliest Flight Arrival | |
Latest Flight Arrival |
Des Moines to Santa Clarita
If you are looking to get guaranteed low prices for Des Moines to Santa Clarita flights then Orbitz is the place to go. We use cutting edge mobile tools to find the best deals on air tickets and to keep you updated on delays and changes.
Get Package Savings by Booking Flights and Hotels at the Same Time
Using the Orbitz Matrix display, you can see how much you will save on flights from Des Moines to Santa Clarita if the discount fare is combined with a hotel. You can also look at hotel reviews, photos and maps of the area, so it will be convenient to make your budget travel plans.
Orbitz for Business Helps Corporations save Money
Orbitz can assist all businesses from the small to major corporations with discounts on flights from Des Moines to Santa Clarita. We fine- tune your needs for Des Moines to Santa Clarita flights and optimize your plans by assessing your business and coming up with ways for you to save on air tickets.
Using Online Check-In Makes Flying Simple
You can use the Orbitz website to check-in for your flights from Des Moines to Santa Clarita. You can also make changes to your schedule or even cancel a flight.
Flights from Des Moines
- Des Moines to Atlanta
- Des Moines to Dallas
- Des Moines to Houston
- Des Moines to Phoenix
- Des Moines to Seattle
- Des Moines to Orlando
- Des Moines to Chicago
- Des Moines to New York
- Des Moines to Los Angeles
- Des Moines to Charlotte
- Des Moines to Detroit
- Des Moines to London
- Des Moines to Sacramento
- Des Moines to Washington
- Des Moines to New Orleans
- Des Moines to Toronto
- Des Moines to San Francisco
- Des Moines to Rome
- Des Moines to Paris
- Des Moines to Hartford
Des Moines Airports
Santa Clarita Airports
More Destinations
- Flights from Miami to Sunland
- Flights from Nashville to Sunland
- Flights from New York to Sunland
- Flights from Orlando to Sunland
- Flights from Portland to Sunland
- Flights from Salt Lake City to Sunland
- Flights from Seoul to Sunland
- Flights from El Paso to Valencia
- Flights from Whitefish to Valencia
- Flights from Amsterdam to Valencia
- Flights from Atlanta to Valencia
- Flights from Boston to Valencia
- Flights from Brussels to Valencia
- Flights from Chicago to Valencia
- Flights from Detroit to Valencia
- Flights from Houston to Valencia
- Flights from London to Valencia
- Flights from Minneapolis - St. Paul to Valencia
- Flights from New York to Valencia
- Flights from Phoenix to Valencia
- Flights from Portland to Valencia
- Flights from Salt Lake City to Valencia
- Flights from San Francisco to Valencia
- Flights from St. Louis to Valencia
- Flights from Vienna to Valencia
- Flights from Sacramento to Valencia
- Flights from Fort Lauderdale to Valencia
- Flights from Newark to Valencia
- Flights from Richmond to Valencia
- Flights from Oakland to Valencia
- Flights from Reno to Valencia
- Flights from Eugene to Valencia
- Flights from Spokane to Valencia
- Flights from Charlottesville to Valencia
- Flights from Baltimore to Simi Valley
- Flights from Boston to Simi Valley
- Flights from Chicago to Simi Valley
- Flights from Columbus to Simi Valley
- Flights from Denver to Simi Valley
- Flights from Houston to Simi Valley
- Flights from Indianapolis to Simi Valley
- Flights from Kansas City to Simi Valley
- Flights from Las Vegas to Simi Valley
- Flights from London to Simi Valley
- Flights from Los Angeles to Simi Valley
- Flights from Miami to Simi Valley
- Flights from Minneapolis - St. Paul to Simi Valley
- Flights from Nashville to Simi Valley
- Flights from New York to Simi Valley
- Flights from Phoenix to Simi Valley
- Flights from Portland to Simi Valley
- Flights from Raleigh to Simi Valley
- Flights from Salt Lake City to Simi Valley
- Flights from St. Louis to Simi Valley
- Flights from Washington to Simi Valley
- Flights from Sacramento to Simi Valley
- Flights from Fort Lauderdale to Simi Valley
- Flights from Newark to Simi Valley
- Flights from Richmond to Simi Valley
- Flights from Panama City to Simi Valley
- Flights from Pensacola to Simi Valley
- Flights from Buffalo to Simi Valley
- Flights from Madison to Simi Valley
- Flights from Little Rock to Simi Valley
- Flights from Spokane to Simi Valley
- Flights from Tucson to Simi Valley
- Flights from Fresno to Simi Valley
- Flights from Grand Rapids to Simi Valley
- Flights from Lansing to Simi Valley
- Flights from Albany to Simi Valley
- Flights from Gainesville to Simi Valley
- Flights from Tallahassee to Simi Valley
- Flights from Charleston to Simi Valley
- Flights from Guadalajara to Van Nuys
- Flights from Yulara to Van Nuys
- Flights from Austin to Van Nuys
- Flights from Baltimore to Van Nuys
- Flights from Charlotte to Van Nuys
- Flights from Cleveland to Van Nuys
- Flights from Denver to Van Nuys
- Flights from Nashville to Van Nuys
- Flights from Phoenix to Van Nuys
- Flights from San Antonio to Van Nuys
- Flights from Tahoe City to Van Nuys
- Flights from Padang to Van Nuys
- Flights from Moncton to Van Nuys
- Flights from Midland to Van Nuys
- Flights from Salem to Van Nuys
- Flights from La Paz to Van Nuys
- Flights from Klamath Falls to Van Nuys
- Flights from Chongqing to Van Nuys
- Flights from Da Nang to Van Nuys
- Flights from Portland to Canyon Country
- Flights from Houston to Encino
- Flights from Las Vegas to Los Angeles
- Flights from New York to Los Angeles
- Flights from San Francisco to Los Angeles
- Flights from Detroit to Stevenson Ranch
- Flights from Salt Lake City to Stevenson Ranch
- Flights from Corpus Christi to Stevenson Ranch
Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.
