$132 Cheap flight deals from Des Moines (DSM) to San Ysidro (SAN)
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This Weekend's Flight Deals from Des Moines to San Ysidro
This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Airfares from $132 One Way, $257 Round Trip from Des Moines to San Ysidro
Prices starting at $257 for return flights and $132 for one-way flights to San Ysidro were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
San Ysidro economy flight packages
Kona Kai San Diego
Jul 19 - Jul 23
Des Moines (DSM) to San Diego (SAN)
Reviewed on Mar 2, 2026
Margaritaville Hotel San Diego Gaslamp Quarter
Jul 19 - Jul 23
Des Moines (DSM) to San Diego (SAN)
Reviewed on Oct 3, 2025
Fairmont Grand Del Mar
Jul 19 - Jul 23
Des Moines (DSM) to San Diego (SAN)
Reviewed on Apr 7, 2026
More About Flying To San Ysidro from Des Moines
Route Information for Flights from Des Moines to San Ysidro
Origin Airport IATA Code | DSM |
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Destination Airport IATA Code | SAN |
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Des Moines to San Ysidro
Orbitz is the best place to find guaranteed low prices on Des Moines to San Ysidro flights. Because of our cutting-edge mobile tools and low fares on domestic and international flights, Orbitz is the best starting point for travelers.
Find Cheap Des Moines to San Ysidro Flights
Orbitz offers free mobile apps for iPhone and Android devices—a great way to find fantastic deals on flights from Des Moines to San Ysidro. Not only that, but you can check the status of your flight or even book low cost hotel rooms with the apps or on m.orbitz.com.
Get Miles and Points for Your Flight
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Discount Travel Planning Made Simple
You will have no problems finding budget flights from Des Moines to San Ysidro on Orbitz.com. If your travel plans are flexible, you can search for fares three days before and after a specific date to find the best price.
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Des Moines Airports
Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.