$91 Cheap flight deals from Des Moines (DSM) to San Mateo (SJC)
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This Weekend's Flight Deals from Des Moines to San Mateo
This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Airfares from $91 One Way, $196 Round Trip from Des Moines to San Mateo
Prices starting at $196 for return flights and $91 for one-way flights to San Mateo were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
San Mateo economy flight packages
Bay Landing San Francisco Airport Hotel
Mar 6 - Mar 9
Des Moines (DSM) to San Francisco (SFO)
Reviewed on Jan 12, 2026
DoubleTree by Hilton Hotel Berkeley Marina
Feb 19 - Feb 26
Des Moines (DSM) to Oakland (OAK)
Reviewed on Nov 10, 2025
SF Central Hotel
Mar 13 - Mar 18
Des Moines (DSM) to San Francisco (SFO)
San Francisco (SFO) to Des Moines (DSM)
Reviewed on Aug 27, 2024
More About Flying To San Mateo from Des Moines
Route Information for Flights from Des Moines to San Mateo
Origin Airport IATA Code | DSM |
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Destination Airport IATA Code | SJC |
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Earliest Flight Arrival | |
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Des Moines to San Mateo
Orbitz guarantees you low prices on flights from Des Moines to San Mateo. In addition to low fares on Des Moines to San Mateo flights, Orbitz offers fantastic savings on hotels, cruises, vacation packages, and more.
Earn Miles While Saving
Besides helping you fly for the lowest fares, Orbitz lets you earn miles for your frequent flyer program for certain flights from Des Moines to San Mateo. If you are a member of the frequent flyer or loyalty program offered by the airline you booked through Orbitz or a partner airline’s, simply add your frequent flyer number to your Orbitz reservation to get credit for your Des Moines to San Mateo flights.
Travel Planning Made Easy
We help take some of the anxiety out of your Des Moines to San Mateo flights with free flight alerts. We will let you know of flight changes and delays to your flights from Des Moines to San Mateo by email, voicemail, or text messages to your mobile phone. Alerts can also be sent to up to six other contacts to keep family and business teams informed.
Use Mobile Apps with Orbitz
Orbitz lets you find the best deals on Des Moines to San Mateo flights while on the go, with our easy-to-use Android and iPhone mobile apps. Easily check flight status, gate numbers, and other flight details all in one place with our app—which is great when you are in a hurry. You can use the apps to access great mobile deals on flights and amazing hotel rooms.
Flights from Des Moines
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Des Moines Airports
Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.