$113 Cheap flight deals from Des Moines (DSM) to San Mateo (SJC)
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This Weekend's Flight Deals from Des Moines to San Mateo
This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Airfares from $113 One Way, $212 Round Trip from Des Moines to San Mateo
Prices starting at $212 for return flights and $113 for one-way flights to San Mateo were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
San Mateo economy flight packages
Embassy Hotel
May 25 - Jun 1
Des Moines (DSM) to San Francisco (SFO)
San Francisco (SFO) to Des Moines (DSM)
Reviewed on Oct 18, 2025
Handlery Union Square Hotel
May 25 - Jun 1
Des Moines (DSM) to San Francisco (SFO)
San Francisco (SFO) to Des Moines (DSM)
Reviewed on Mar 23, 2026
The Donatello
May 25 - Jun 1
Des Moines (DSM) to San Francisco (SFO)
San Francisco (SFO) to Des Moines (DSM)
Reviewed on Mar 4, 2026
More About Flying To San Mateo from Des Moines
Route Information for Flights from Des Moines to San Mateo
Origin Airport IATA Code | DSM |
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Destination Airport IATA Code | SJC |
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Des Moines to San Mateo
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Best Deals At Your Fingertips
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Flights from Des Moines
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Des Moines Airports
Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.