
$253 Cheap flight deals from Des Moines (DSM) to Irmo (CAE)
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Airfares from $253 One Way, $269 Round Trip from Des Moines to Irmo
Prices starting at $269 for return flights and $253 for one-way flights to Irmo were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Irmo economy flight packages

Sleep Inn Columbia
Feb 13 - Feb 16
Des Moines (DSM) to Columbia (CAE)
Reviewed on Nov 19, 2025

Graduate by Hilton Columbia SC
Feb 13 - Feb 16
Des Moines (DSM) to Columbia (CAE)
Reviewed on Jul 29, 2025

Courtyard by Marriott Columbia Downtown at USC
Feb 13 - Feb 16
Des Moines (DSM) to Columbia (CAE)
Reviewed on Sep 26, 2025
More About Flying To Irmo from Des Moines
Route Information for Flights from Des Moines to Irmo
Origin Airport IATA Code | DSM |
|---|---|
Destination Airport IATA Code | CAE |
Distance | |
Direct Flight Airlines | |
Earliest Flight Arrival | |
Latest Flight Arrival |
Des Moines to Irmo
Des Moines to Irmo flights are offered at fantastic discount by Orbitz. Book air tickets now and cut those extra costs out of your travel budget to ensure a rewarding travel experience. With guaranteed low prices like these, can you afford to miss this discount?
Book cheap flights from Des Moines to Irmo
Cheap airfares are available on flights from Des Moines to Irmo. Use Orbitz to find the best flights that suit both your budget and the travel times that you need. Travelers who are looking for discounted rates on domestic or international flights need to look no further than Orbitz.
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Get a great package with your Des Moines to Irmo flights
With frequent updates on your flight status, including delays and changes in bookings, traveling becomes more hassle-free than ever. Not only do we offer huge discounted deals on flights from Des Moines to Irmo, we also have fantastic savings on vacation packages, hotel room, cruises, activities, and car rentals so you can pick and choose and create the best travel package for you.
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Irmo Airports
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Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.

