$203 Cheap flight deals from Des Moines (DSM) to Port Saint Lucie (PBI)
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Airfares from $203 One Way, $412 Round Trip from Des Moines to Port Saint Lucie
Prices starting at $412 for return flights and $203 for one-way flights to Port Saint Lucie were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Port Saint Lucie economy flight packages
Hawthorn Extended Stay by Wyndham West Palm Beach Airport
May 24 - May 27
Des Moines (DSM) to West Palm Beach (PBI)
Reviewed on Jan 21, 2026
Hilton Garden Inn Palm Beach Gardens
May 24 - May 27
Des Moines (DSM) to West Palm Beach (PBI)
Reviewed on Feb 23, 2026
More About Flying To Port Saint Lucie from Des Moines
Route Information for Flights from Des Moines to Port Saint Lucie
Origin Airport IATA Code | DSM |
|---|---|
Destination Airport IATA Code | PBI |
Distance | |
Direct Flight Airlines | |
Earliest Flight Arrival | |
Latest Flight Arrival |
Des Moines to Port Saint Lucie
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Guaranteed low prices for Des Moines to Port Saint Lucie flights makes Orbitz the perfect online budget travel source.
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Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.